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Standards Ontologies Notations
Hepatic triacylglycerol lipase

Summary
UniProt ID
P11150
Gene Symbol
  • LIPC
  • HTGL
Organism
Homo sapiens (human)
External Links
PubChem
P11150
SwissLipids
The Human Metabolome Database
HMDBP00226
Annotation
Keyword
  • Direct protein sequencing
  • Disease variant
  • Glycoprotein
  • HDL
  • Heparin-binding
  • Hydrolase
  • Lipid degradation
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying entries 11 - 12 of 12 in total
GO Term
chylomicron remnant clearance
triglyceride homeostasis
Displaying entry 11 - 11 of 11 in total
GO Term
phosphatidyl phospholipase B activity
Annotation information from UniProt.
Sequence
MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
42 N-linked (GlcNAc...) asparagine
78 N-linked (GlcNAc...) asparagine
362 N-linked (GlcNAc...) asparagine
397 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Assembly of active LPL and LIPC lipase complexes Homo sapiens
Chylomicron clearance Homo sapiens
Disease
Displaying entries 1 - 10 of 124 in total
DO ID Disease Name Source
DOID:0040085 bacterial sepsis
DOID:0050328 congenital hypothyroidism
DOID:0050747 obsolete lymphoplasmacytic lymphoma
DOID:0050782 Zollinger-Ellison syndrome
DOID:0050830 peripheral artery disease
DOID:0060224 atrial fibrillation
DOID:0060250 idiopathic scoliosis
DOID:0080199 colorectal carcinoma
DOID:0080348 Alzheimer's disease 1
DOID:0110035 Alzheimer's disease 2
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024