Hepatic triacylglycerol lipase

Summary
UniProt ID
P11150
Gene Symbol
  • LIPC
  • HTGL
Organism
Homo sapiens (human)
External Links
PubChem
P11150
SwissLipids
The Human Metabolome Database
HMDBP00226
Annotation
Keyword
  • Direct protein sequencing
  • Disease variant
  • Glycoprotein
  • HDL
  • Heparin-binding
  • Hydrolase
  • Lipid degradation
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Sequence
MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
42 N-linked (GlcNAc...) asparagine
78 N-linked (GlcNAc...) asparagine
362 N-linked (GlcNAc...) asparagine
397 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Assembly of active LPL and LIPC lipase complexes Homo sapiens
Chylomicron clearance Homo sapiens
Disease
Displaying entries 31 - 40 of 124 in total
DO ID Disease Name Source
DOID:0110751 type 1 diabetes mellitus 12
DOID:0110752 type 1 diabetes mellitus 13
DOID:0110753 type 1 diabetes mellitus 15
DOID:0110754 type 1 diabetes mellitus 17
DOID:0110755 type 1 diabetes mellitus 18
DOID:0110756 type 1 diabetes mellitus 19
DOID:0110757 type 1 diabetes mellitus 20
DOID:0110758 type 1 diabetes mellitus 21
DOID:0110759 type 1 diabetes mellitus 22
DOID:0110760 type 1 diabetes mellitus 23

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024