Acetylcholinesterase

Summary
UniProt ID
P22303
Gene Symbol
  • ACHE
Organism
Homo sapiens (human)
External Links
GlyGen
P22303
PubChem
P22303
The Human Metabolome Database
HMDBP00524
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Blood group antigen
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • GPI-anchor
  • Neurotransmitter degradation
  • Nucleus
  • Reference proteome
  • Secreted
  • Serine esterase
  • Signal
  • Synapse
Gene Ontology (GO)
Sequence
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
296 N-linked (GlcNAc...) asparagine
381 N-linked (GlcNAc...) asparagine
495 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Neurotransmitter clearance Homo sapiens
Synthesis of PC Homo sapiens
Synthesis, secretion, and deacylation of Ghrelin Homo sapiens
Disease
Displaying entries 31 - 40 of 359 in total
DO ID Disease Name Source
DOID:0060814 Wilson-Turner syndrome
DOID:0060891 Parkinson's disease 19A
DOID:0060895 Parkinson's disease 4
DOID:0060896 Parkinson's disease 23
DOID:0070123 congenital nongoitrous hypothyroidism 4
DOID:0070124 congenital nongoitrous hypothyroidism 2
DOID:0070125 congenital nongoitrous hypothyroidism 5
DOID:0070126 congenital nongoitrous hypothyroidism 1
DOID:0070127 congenital nongoitrous hypothyroidism 3
DOID:0070128 congenital nongoitrous hypothyroidism 6

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024