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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Histone H2AX
Summary
- UniProt ID
- P27661
- Gene Symbol
-
- H2ax
- H2a.x
- H2afx
- Hist5-2ax
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell cycle
- DNA recombination
- DNA repair
- Isopeptide bond
- Meiosis
- Nucleosome core
- Nucleus
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| male germ cell nucleus |
| nucleus |
| chromosome |
| nuclear speck |
| chromosome, telomeric region |
| nucleosome |
| condensed nuclear chromosome |
| XY body |
| nucleoplasm |
| GO Term |
|---|
| enzyme binding |
| structural constituent of chromatin |
| nucleosomal DNA binding |
| protein heterodimerization activity |
| damaged DNA binding |
| histone binding |
Sequence
MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKSSATVGPKAPAVGKKASQASQEY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cleavage of the damaged purine | Mus musculus |
| Condensation of Prophase Chromosomes | Mus musculus |
| DNA Damage/Telomere Stress Induced Senescence | Mus musculus |
| Deposition of new CENPA-containing nucleosomes at the centromere | Mus musculus |
| G2/M DNA damage checkpoint | Mus musculus |
| Inhibition of DNA recombination at telomere | Mus musculus |
| Nonhomologous End-Joining (NHEJ) | Mus musculus |
| PRC2 methylates histones and DNA | Mus musculus |
| Processing of DNA double-strand break ends | Mus musculus |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | Mus musculus |
