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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Protein disulfide-isomerase A3
Summary
- UniProt ID
- P30101
- Gene Symbol
-
- PDIA3
- ERP57
- ERP60
- GRP58
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Adaptive immunity
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Isomerase
- Methylation
- Phosphoprotein
- Redox-active center
- Reference proteome
- Repeat
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular exosome |
| recycling endosome membrane |
| Tapasin-ERp57 complex |
| phagocytic vesicle |
| MHC class I peptide loading complex |
| endoplasmic reticulum |
| endoplasmic reticulum lumen |
| focal adhesion |
| extracellular space |
| nucleus |
Sequence
MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 90 |
|
|
||
| 95 |
|
|||
| 102 |
|
|||
| 120 |
|
|||
| 126 |
|
|||
| 215 |
|
|||
| 219 |
|
|||
| 449 |
|
|||
| 452 |
|
|||
| 456 |
|
G57321FI
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | Homo sapiens |
| Calnexin/calreticulin cycle | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14557 | primary pulmonary hypertension | |
| DOID:1470 | major depressive disorder | |
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1749 | squamous cell carcinoma | |
| DOID:1825 | childhood absence epilepsy | |
| DOID:1826 | epilepsy | |
| DOID:1883 | hepatitis C |
