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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
TGF-beta receptor type-2
Summary
- UniProt ID
- P38438
- Gene Symbol
-
- Tgfbr2
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P38438
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| membrane |
| receptor complex |
| caveola |
| membrane raft |
| external side of plasma membrane |
| cell surface |
| transforming growth factor beta ligand-receptor complex |
| GO Term |
|---|
| molecular adaptor activity |
| activin receptor activity |
| mitogen-activated protein kinase kinase kinase binding |
| activin binding |
| protein homodimerization activity |
| SMAD binding |
Sequence
MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDLMAGDNSGAVKLPQLCKFCDVTLSTCDNQKSCMSNCSVTSICEKPQEVCVAVWRKNDKNITLETVCHDPKFTYHGFTLEDATSPTCVMKEKKRAGETFFMCSCNTEECNDYIIFNEEYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIAIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLKHENILQFLTAEERKTEMGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSELEHPDRLSGRSCSQEKIPEDGSLNTTK
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downregulation of TGF-beta receptor signaling | Rattus norvegicus |
| TGF-beta receptor signaling activates SMADs | Rattus norvegicus |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Rattus norvegicus |
