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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Epidermal growth factor receptor
Summary
- UniProt ID
- Q01279
- Gene Symbol
-
- Egfr
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003854
- GlyConnect
- GlyGen
- Q01279
- PubChem
- Q01279
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Developmental protein
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Hydroxylation
- Isopeptide bond
- Methylation
- Nucleus
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| nucleus |
| plasma membrane |
| endocytic vesicle |
| nuclear membrane |
| cell junction |
| receptor complex |
| basolateral plasma membrane |
| apical plasma membrane |
| early endosome membrane |
| GO Term |
|---|
| identical protein binding |
| epidermal growth factor receptor activity |
| epidermal growth factor binding |
| actin filament binding |
| integrin binding |
| calmodulin binding |
| ATP binding |
| protein phosphatase binding |
Sequence
MRPSGTARTTLLVLLTALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGCEVWPSGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNGSCRVKEDAFLQRYSSDPTGAVTEDNIDDAFLPVPEYVNQSVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVGNPEYLNTAQPTCLSSGFNSPALWIQKGSHQMSLDNPDYQQDFFPKETKPNGIFKGPTAENAEYLRVAPPSSEFIGA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 128 | N-linked (GlcNAc...) asparagine |
|
||
| 175 | N-linked (GlcNAc...) asparagine | |||
| 196 | N-linked (GlcNAc...) asparagine | |||
| 234 |
|
|
||
| 352 | N-linked (GlcNAc...) asparagine | |||
| 413 | N-linked (GlcNAc...) asparagine |
|
||
| 444 | N-linked (GlcNAc...) asparagine | |||
| 528 | N-linked (GlcNAc...) asparagine | |||
| 568 | N-linked (GlcNAc...) asparagine | |||
| 603 | N-linked (GlcNAc...) asparagine |
G90659AW
G02815KT
G80920RR
G39188ZX
G24193ZC
G43223CG
G27947YN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| GRB2 events in EGFR signaling | Mus musculus |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | Mus musculus |
| PI3K events in ERBB2 signaling | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| PTK6 promotes HIF1A stabilization | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
| SHC1 events in EGFR signaling | Mus musculus |
| SHC1 events in ERBB2 signaling | Mus musculus |
| Signal transduction by L1 | Mus musculus |
