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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hyaluronan synthase 2
Summary
- UniProt ID
- Q92819
- Gene Symbol
-
- HAS2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q92819
- The Human Metabolome Database
- HMDBP01874
- The O-GlcNAc Database
- Q92819
- O-GlcNAcAtlas
- Q92819
Annotation
- Keyword
-
- Cell membrane
- Chromosomal rearrangement
- Endoplasmic reticulum
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Isopeptide bond
- Lysosome
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to interleukin-1 |
| cellular response to fluid shear stress |
| positive regulation of substrate adhesion-dependent cell spreading |
| positive regulation of monocyte aggregation |
| GO Term |
|---|
| Golgi membrane |
| lysosome |
| Golgi apparatus |
| plasma membrane |
| cytoplasmic vesicle |
| extracellular vesicle |
| plasma membrane raft |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| hyaluronan synthase activity |
| identical protein binding |
Sequence
MHCERFLCILRIIGTTLFGVSLLLGITAAYIVGYQFIQTDNYYFSFGLYGAFLASHLIIQSLFAFLEHRKMKKSLETPIKLNKTVALCIAAYQEDPDYLRKCLQSVKRLTYPGIKVVMVIDGNSEDDLYMMDIFSEVMGRDKSATYIWKNNFHEKGPGETDESHKESSQHVTQLVLSNKSICIMQKWGGKREVMYTAFRALGRSVDYVQVCDSDTMLDPASSVEMVKVLEEDPMVGGVGGDVQILNKYDSWISFLSSVRYWMAFNIERACQSYFGCVQCISGPLGMYRNSLLHEFVEDWYNQEFMGNQCSFGDDRHLTNRVLSLGYATKYTARSKCLTETPIEYLRWLNQQTRWSKSYFREWLYNAMWFHKHHLWMTYEAIITGFFPFFLIATVIQLFYRGKIWNILLFLLTVQLVGLIKSSFASCLRGNIVMVFMSLYSVLYMSSLLPAKMFAIATINKAGWGTSGRKTIVVNFIGLIPVSVWFTILLGGVIFTIYKESKRPFSESKQTVLIVGTLLYACYWVMLLTLYVVLINKCGRRKKGQQYDMVLDV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 180 |
|
|||
| 221 | O-linked (GlcNAc) serine |
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Hyaluronan biosynthesis and export | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1657 | ventricular septal defect | |
| DOID:1682 | congenital heart disease | |
| DOID:1749 | squamous cell carcinoma | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:1909 | melanoma | |
| DOID:1920 | hyperuricemia | |
| DOID:1936 | atherosclerosis | |
| DOID:2224 | essential thrombocythemia | |
| DOID:2348 | arteriosclerotic cardiovascular disease | |
| DOID:2349 | arteriosclerosis |
