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Tyrosine-protein kinase receptor

Summary

UniProt ID

E9QNX9

Gene Symbol

Igf1r

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0002632

Annotation

Keyword

ATP-binding
Cleavage on pair of basic residues
Glycoprotein
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying entries **11 - 20** of 44 in total

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GO Term
positive regulation of protein-containing complex disassembly
response to alkaloid
positive regulation of smooth muscle cell proliferation
positive regulation of DNA metabolic process
cellular response to glucose stimulus
cellular response to estradiol stimulus
cellular response to progesterone stimulus
cellular response to testosterone stimulus
positive regulation of steroid hormone biosynthetic process
negative regulation of hepatocyte apoptotic process

Displaying **all 7** entries
GO Term
T-tubule
caveola
alphav-beta3 integrin-IGF-1-IGF1R complex
insulin receptor complex
axon
intracellular membrane-bounded organelle
neuronal cell body

Displaying entries **1 - 10** of 13 in total

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GO Term
insulin-like growth factor I binding
identical protein binding
insulin receptor substrate binding
G-protein alpha-subunit binding
insulin-like growth factor receptor activity
insulin-like growth factor binding
insulin receptor binding
ATP binding
phosphatidylinositol 3-kinase binding
insulin receptor activity

Annotation information from UniProt.

Sequence

MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGDLCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDDECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMEPENMESVPLDPSASSASLPLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
245		22823882
314
608		22823882 23002422
623		22823882 23002422
641		22823882
748		22823882 23002422
757		22823882 23002422
765		22823882 23002422
901		17406563 22823882 23002422