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Integrin beta-3

Summary

UniProt ID

O54890

Gene Symbol

Itgb3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003145

GlyConnect

2405

GlyGen

O54890

PubChem

O54890

RaftProt

O54890

Annotation

Keyword

3D-structure
Calcium
Cell adhesion
Cell junction
Cell membrane
Cell projection
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Magnesium
Metal-binding
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **21 - 30** of 58 in total

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GO Term
apolipoprotein A-I-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to mechanical stimulus
positive regulation of glomerular mesangial cell proliferation
maintenance of postsynaptic specialization structure
regulation of postsynaptic neurotransmitter receptor internalization
regulation of postsynaptic neurotransmitter receptor diffusion trapping
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

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GO Term
integrin complex
external side of plasma membrane
cell surface
ruffle membrane
integrin alpha9-beta1 complex
synapse
postsynaptic membrane
receptor complex
synaptic membrane
glycinergic synapse

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GO Term
metal ion binding
vascular endothelial growth factor receptor 2 binding
extracellular matrix binding
fibrinogen binding
C-X3-C chemokine binding
insulin-like growth factor I binding
identical protein binding
fibronectin binding
protein disulfide isomerase activity
fibroblast growth factor binding

Annotation information from UniProt.

Sequence

MRAQWPGQLWAALLALGALAGVVVGESNICTTRGVNSCQQCLAVSPVCAWCSDETLSQGSPRCNLKENLLKDNCAPESIEFPVSEAQILEARPLSSKGSGSSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMYISPPQAIKNPCYNMKNACLPMFGYKHVLTLTDQVSRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGHCHIGTDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCVGLKIGDTVSFSIEAKVRGCPQEKEQSFTIKPVGFKDSLTVQVTFDCDCACQAFAQPSSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPSQQEECSPKEGQPICSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQPGSYGDTCEKCPTCPDACSFKKECVECKKFNRGTLHEENTCSRYCRDDIEQVKELTDTGKNAVNCTYKNEDDCVVRFQYYEDTSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
477		23002422
584		22823882
679		17406563 22823882

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
ECM proteoglycans	Mus musculus
Elastic fibre formation	Mus musculus
GRB2:SOS provides linkage to MAPK signaling for Integrins	Mus musculus
Integrin cell surface interactions	Mus musculus
Integrin signaling	Mus musculus
MAP2K and MAPK activation	Mus musculus
Molecules associated with elastic fibres	Mus musculus
PECAM1 interactions	Mus musculus
Platelet degranulation	Mus musculus
Signal transduction by L1	Mus musculus

GlyTouCan

GlyComb

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UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements