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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Major prion protein
Summary
- UniProt ID
- P04156
- Gene Symbol
-
- PRNP
- ALTPRP
- PRIP
- PRP
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011355
- GlyConnect
- GlyGen
- P04156
- PubChem
- P04156
- The Human Metabolome Database
- HMDBP02352
- The O-GlcNAc Database
- P04156
- RaftProt
- P04156
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Amyloidosis
- Cell membrane
- Copper
- Direct protein sequencing
- Disease variant
- Disulfide bond
- GPI-anchor
- Golgi apparatus
- Growth arrest
- Metal-binding
- Prion
- Reference proteome
- Repeat
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| plasma membrane |
| nuclear membrane |
| terminal bouton |
| intracellular membrane-bounded organelle |
| dendrite |
| membrane raft |
Sequence
MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | Homo sapiens |
| NCAM1 interactions | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1686 | glaucoma | |
| DOID:1687 | neovascular glaucoma | |
| DOID:1749 | squamous cell carcinoma | |
| DOID:1768 | conversion disorder | |
| DOID:1793 | pancreatic cancer | |
| DOID:1826 | epilepsy |
