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Phosphatidylcholine-sterol acyltransferase

Summary
UniProt ID
P04180
Gene Symbol
  • LCAT
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011357
GlyConnect
GlyGen
P04180
PubChem
P04180
SwissLipids
The Human Metabolome Database
HMDBP00069
Annotation
Keyword
  • 3D-structure
  • Acyltransferase
  • Cholesterol metabolism
  • Corneal dystrophy
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
44
296
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
HDL remodeling Homo sapiens
Disease
Displaying entries 21 - 30 of 150 in total
DO ID Disease Name Source
DOID:0110047 Alzheimer's disease 14
DOID:0110048 Alzheimer's disease 15
DOID:0110148 Charcot-Marie-Tooth disease type 1A
DOID:0110149 Charcot-Marie-Tooth disease type 1F
DOID:0110150 Charcot-Marie-Tooth disease type 1D
DOID:0110151 Charcot-Marie-Tooth disease type 1C
DOID:0110152 Charcot-Marie-Tooth disease type 1B
DOID:0110153 Charcot-Marie-Tooth disease type 1E
DOID:0110154 Charcot-Marie-Tooth disease type 2A1
DOID:0110155 Charcot-Marie-Tooth disease type 2A2A
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024