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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neural cell adhesion molecule 1
Summary
- UniProt ID
- P13591
- Gene Symbol
-
- NCAM1
- NCAM
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011515
- GlyConnect
- GlyGen
- P13591
- PubChem
- P13591
- RaftProt
- P13591
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Disulfide bond
- GPI-anchor
- Host cell receptor for virus entry
- Host-virus interaction
- Immunoglobulin domain
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell adhesion |
| regulation of semaphorin-plexin signaling pathway |
| commissural neuron axon guidance |
| epithelial to mesenchymal transition |
| GO Term |
|---|
| Golgi membrane |
| extracellular region |
| plasma membrane |
| membrane |
| collagen-containing extracellular matrix |
| cytosol |
| external side of plasma membrane |
| cell surface |
| GO Term |
|---|
| virus receptor activity |
Sequence
MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLSTGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 459 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| NCAM signaling for neurite out-growth | Homo sapiens |
| NCAM1 interactions | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| Signal transduction by L1 | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:627 | severe combined immunodeficiency | |
| DOID:640 | encephalomyelitis | |
| DOID:6536 | plasma cell neoplasm | |
| DOID:657 | adenoma | |
| DOID:6658 | pulmonary large cell neuroendocrine carcinoma | |
| DOID:6688 | autoimmune lymphoproliferative syndrome | |
| DOID:6713 | cerebrovascular disease | |
| DOID:676 | juvenile rheumatoid arthritis | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:707 | B-cell lymphoma |
