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Fibroblast growth factor receptor 1

Summary

UniProt ID

P16092

Gene Symbol

Fgfr1
Flg

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003422

GlyConnect

2314

GlyGen

P16092

PubChem

P16092

The O-GlcNAc Database

P16092

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Heparin-binding
Immunoglobulin domain
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **21 - 30** of 80 in total

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GO Term
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
regulation of extrinsic apoptotic signaling pathway in absence of ligand
orbitofrontal cortex development
motogenic signaling involved in postnatal olfactory bulb interneuron migration
ventricular zone neuroblast division
embryonic limb morphogenesis
protein autophosphorylation
positive regulation of MAP kinase activity
regulation of lateral mesodermal cell fate specification

Displaying **all 6** entries
GO Term
cytosol
nucleus
plasma membrane
cytoplasmic vesicle
receptor complex
perinuclear region of cytoplasm

Displaying **all 10** entries
GO Term
signaling receptor binding
heparin binding
protein-containing complex binding
SH2 domain binding
receptor-receptor interaction
cell adhesion molecule binding
protein homodimerization activity
fibroblast growth factor receptor activity
fibroblast growth factor binding
ATP binding

Annotation information from UniProt.

Sequence

MWGWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSIPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTQLANSGLKRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
227		22823882
240		22823882
264		23002422

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 14** of 14 in total

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Pathway Name	Organism
Phospholipase C-mediated cascade: FGFR1	Mus musculus
RAF/MAP kinase cascade	Mus musculus
SHC-mediated cascade:FGFR1	Mus musculus
Signal transduction by L1	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements