WNT ligand biogenesis and trafficking
|
|
|
- Zwnt[a]
- cgi100
- cgi1000
- int-1
- tmed5
- wnt-1
- wnt-10a
- wnt-2
- wnt-4
- wnt-5
- wnt-8
- wnt-8b
- wnt1
- wnt10a
- wnt10b
- wnt2
- wnt2bb
- wnt3
- wnt3 l
- wnt3a
- wnt3l
- wnt4
- wnt4a
- wnt5
- wnt5a
- wnt5b
- wnt7a
- wnt7aa
- wnt8
- wnt8a
- wnt8b
- wnt9a
- wnt9b
- wnt[a]
- zgc:153617
- zgc:63936
|
|
RND1 GTPase cycle
|
|
|
- Aldh-III
- CAV1
- LOC100004299
- aldh3a2
- aldh3a2a
- arhgap35a
- arhgap5
- arms
- cav1
- cpda
- dspa
- epha2
- epha2a
- fam83b
- fb36h09
- fi33b05
- flot2a
- frs3
- heg
- id:ibd5152
- im:6911394
- kidins220
- kidins220b
- pik3r1
- pik3r2
- plxna1
- plxna1b
- rbm39a
- rbm39b
- rnd1a
- rnd1b
- rnd1l
- rnpc2
- rnpc2l
- rras2
- rtk6
- scg10
- scgn10
- si:dkey-181m9.10
- stb2
- stbm
- stip1
- stmn2
- stmn2b
- tfr1a
- tmem59
- tri
- vangl1
- vangl2
- wu:fa97g07
- wu:fb09c08
- wu:fb36h09
- wu:fb65b05
- wu:fc06b11
- wu:fc07c04
- wu:fc47b08
- wu:fi33b05
- wu:fk50c04
- zgc:110132
- zgc:110215
- zgc:112139
- zgc:113117
- zgc:153089
- zgc:194621
- zgc:55780
- zgc:92064
- zgc:92133
|
|
Neurophilin interactions with VEGF and VEGFR
|
|
|
- flk1b
- kdr
- kdrb
- np-1
- nrp1
- nrp1a
|
|
RND2 GTPase cycle
|
|
|
- Aldh-III
- CAV1
- LOC100004299
- Rho
- aldh3a2
- aldh3a2a
- arhgap1
- arhgap35a
- arhgap5
- arhn
- arms
- cav1
- ckap4
- dsg2
- dsg2.1
- dsga
- epha2
- epha2a
- fam83b
- fk03b12
- fk61c06
- frs3
- heg
- id:ibd5152
- kctd13
- kidins220
- kidins220b
- llk
- lrrc1
- nudc
- pik3r1
- pik3r2
- plxnd1
- rbm39a
- rbm39b
- rnd2
- rnpc2
- rnpc2l
- rtk6
- scrb1
- scrib
- si:dz163l24.1
- stb2
- stbm
- tfr1a
- tnfaip1
- tri
- vangl1
- vangl2
- wu:cegs2891
- wu:fa97g07
- wu:fb09c08
- wu:fb65b05
- wu:fc06b11
- wu:fc07c04
- wu:fi06b02
- wu:fk03b12
- wu:fk61c06
- zgc:101523
- zgc:110361
- zgc:112139
- zgc:113117
- zgc:153204
- zgc:55302
- zgc:55780
- zgc:56099
- zgc:77379
- zgc:85670
- zgc:92064
|
|
FGFR1b ligand binding and activation
|
|
|
- GIPC
- TIP-2
- fgf-1
- fgf-10
- fgf-3
- fgf1
- fgf10
- fgf10a
- fgf2
- fgf22
- fgf3
- fgfr1
- fgfr1a
- gipc1
- rgs19ip1
- si:ch73-18k18.1
- si:dkey-21e2.2
- si:dkeyp-74c5.3
- tgfbr3
- wu:fd11d03
- zgc:109774
|
|
RAF/MAP kinase cascade
|
|
|
- EGFR12
- EGFR15
- ERK1
- NRG2b
- ang1
- angpt1
- btc
- c-met
- cmet
- dob
- egfr
- egfra
- epgn
- erbb2
- erbb3
- erbb3b
- erbb4
- erbb4a
- fb18e12
- fc89b01
- fgf-1
- fgf-10
- fgf-3
- fgf-8
- fgf1
- fgf10
- fgf10a
- fgf16
- fgf17
- fgf17b
- fgf18
- fgf18a
- fgf2
- fgf20a
- fgf22
- fgf23
- fgf3
- fgf4
- fgf5
- fgf6b
- fgf7
- fgf8
- fgf8a
- fgfr1
- fgfr1a
- fgfr2
- fgfr3
- fgfr4
- fi06b09
- fj59e07
- frs3
- grb2
- grb2a
- grb2b
- hbegfa
- hrasb
- hrasl
- id:ibd5158
- kit
- kita
- kitla
- kitlga
- kl
- mapk1
- mapk3
- met
- nras
- nrg2b
- pdgfab
- pdgfbb
- pdgfra
- pik3ca
- pik3cb
- pik3r1
- pik3r2
- ranbp9
- rasgrf2
- rasgrp3
- rgl1
- si:ch211-227n20.1
- si:dkey-21e2.2
- si:dkeyp-74c5.3
- sos1
- sparse
- tek
- tie-2
- tie2
- wu:fb05c08
- wu:fb18e12
- wu:fb34e06
- wu:fb65b05
- wu:fc32c12
- wu:fc76g06
- wu:fc89b01
- wu:fd11d03
- wu:fi06b09
- wu:fj59e07
- wu:fv70f10
- zERK1
- zERK2
- zgc:103549
- zgc:109774
- zgc:110734
- zgc:153249
- zgc:158274
- zgc:194535
- zgc:63601
- zgc:73077
|
|
NFG and proNGF binds to p75NTR
|
|
|
|
|
G beta:gamma signalling through PI3Kgamma
|
|
|
- akt2
- akt3b
- cb945
- pdpk1b
- rhoac
- zgc:77318
|
|
Phospholipase C-mediated cascade; FGFR3
|
|
|
- dob
- fc89b01
- fgf-1
- fgf-8
- fgf1
- fgf16
- fgf17
- fgf17b
- fgf18
- fgf18a
- fgf2
- fgf20a
- fgf23
- fgf4
- fgf5
- fgf8
- fgf8a
- fgfr3
- fj46f04
- id:ibd5158
- plcg1
- wu:fb05c08
- wu:fc89b01
- wu:fj46f04
- wu:fj57a05
|
|
Myogenesis
|
|
|
- Ctnna2
- MEF2B
- R-cadherin
- boc
- cb507
- cb553
- cb641
- cdh2
- cdh4
- cdon
- ctnna1
- ctnnb1
- etID309781.16
- fa16d03
- fk53b11
- mapk11
- mapk12b
- mapk14
- mapk14b
- mef2D
- mef2b
- mef2d
- mrf4
- myf-5
- myf5
- myf6
- myod
- myod1
- myog
- pac
- rcad
- si:ch211-125m10.1
- si:dkey-14d8.5
- tcf12
- tcf3a
- tcf3b
- wu:fa10c03
- wu:fa16d03
- wu:fb94b11
- wu:fc50h03
- wu:fk53b11
- zgc:100763
- zgc:109833
- zgc:110509
- zgc:136316
- zgc:158240
- zgc:86905
|
|
VEGF binds to VEGFR leading to receptor dimerization
|
|
|
- figf
- flk1b
- flt-4
- flt4
- kdr
- kdrb
- vegf
- vegf-d
- vegfa
- vegfaa
- vegfc
- vegfd
- vegfr3
|
|
Signaling by PDGF
|
|
|
- furin
- furina
- pdgfab
- pdgfbb
- pdgfra
- ptpn12
- si:dkey-281a24.5
- wu:fc32c12
- zgc:153249
- zgc:65856
- zgc:77437
|
|
MHC class II antigen presentation
|
|
|
- Ap1m1
- CTSB
- GILT
- Iclp-1
- MHCII
- Ppgb
- ap1g2
- ap1m2
- ap1s1
- ap1s2
- arf1
- b2m
- canx
- catD
- cb173
- cb271
- cb420
- cb460
- cb912
- cd74a
- clta
- ctsa
- ctsb
- ctsba
- ctsc
- ctsd
- ctsf
- ctsh
- ctsk
- ctsl
- ctsl.1
- ctss2.1
- ctssb.1
- ctssb1
- dnm2
- dnm2b
- dnm2l
- fc07e03
- fc38f10
- fc44c02
- fc47h06
- fj40d12
- hla-dpa1
- hm:zewp0159
- iclp1
- id:ibd1201
- ifi30
- ik:tdsubc_1h2
- im:6797184
- im:6910535
- lgmn
- mhc2b
- mhc2d8.45b1
- mhc2daa
- mhc2dgb
- ns:zf-a41
- sar1a
- sar1ab
- sb:cb146
- sb:cb173
- sb:cb271
- sb:cb420
- sec13
- sec13l1
- sec23a
- sec31a
- sec31l1
- sec31p
- si:busm1-160c18.10
- si:busm1-194e12.12
- si:busm1-194e12.8
- si:busm1-228j01.6
- si:busm1-266f07.2
- si:busm1-48c11.4
- si:dkey-239j18.2
- si:dkey-269i1.3
- si:dz160c18.10
- si:dz194e12.12
- si:dz194e12.8
- si:dz228j01.6
- si:dz266f07.2
- si:dz48c11.4
- si:zc14a17.4
- wu:fa08f09
- wu:fa13g05
- wu:fa93a04
- wu:fa95f03
- wu:fa98g05
- wu:fb08b05
- wu:fb11f09
- wu:fb12a01
- wu:fb13d06
- wu:fb33e02
- wu:fb33g02
- wu:fb34e12
- wu:fb34g12
- wu:fb36c08
- wu:fb61d08
- wu:fb78h01
- wu:fb93e11
- wu:fb94g06
- wu:fc07e03
- wu:fc38f10
- wu:fc44c02
- wu:fc47h06
- wu:fd13d02
- wu:fd19a08
- wu:fe06b12
- wu:fi17f10
- wu:fj17b09
- wu:fj40d12
- wu:fj48d06
- wu:fj58d01
- wu:fj91g05
- wu:fj92g08
- wu:fk94e07
- zf-a41
- zgc:101701
- zgc:103537
- zgc:110367
- zgc:110650
- zgc:112226
- zgc:112369
- zgc:113853
- zgc:123061
- zgc:123302
- zgc:153093
- zgc:55862
- zgc:56704
- zgc:63524
- zgc:63980
- zgc:65802
- zgc:65809
- zgc:73358
- zgc:76953
- zgc:77181
- zgc:77233
- zgc:77925
- zgc:85689
- zgc:85774
- zgc:92089
- zmp:0000001138
|
|
RHO GTPases activate PKNs
|
|
|
- CPI-17
- Pp1alpha-96A
- im:7147597
- mbs
- mypt1
- pdpk1b
- pkn1b
- pkn2
- pkn3
- ppp1cbl
- ppp1r12a
- ppp1r14a
- ppp1r14aa
- prk2
- prkcl2
- rac1
- rac1a
- rhoac
- wu:fa14b10
- wu:fd16e02
- zgc:110700
- zgc:55823
- zgc:55917
- zgc:64169
- zgc:77318
- zgc:86934
|
|
G alpha (12/13) signalling events
|
|
|
- adra1bb
- arhgef11
- arhgef18
- arhgef18a
- arhgef37
- arhgef39
- fgd4
- fgd4a
- fj59e07
- gna12
- gna12a
- gna12l
- gna13
- gna13a
- rasgrf2
- rhoac
- rock2
- rock2a
- rok2
- si:ch211-194i18.1
- si:dkey-57m7.1
- sos1
- tbxa2r
- trio
- wu:fc21e04
- wu:fe25e05
- wu:fj05f11
- wu:fj59e07
- zgc:103517
- zgc:103685
- zgc:112436
- zgc:158274
- zgc:85686
|
|
Downstream signal transduction
|
|
|
- Stat5
- crk
- crkl
- fb18e12
- fb34h10
- fc05a01
- fd20h08
- fi19g05
- fj46f04
- fj59e07
- grb2
- grb2a
- grb2b
- hrasb
- hrasl
- im:7147817
- nck1b
- nck2b
- nras
- pdgfab
- pdgfbb
- pdgfra
- pik3ca
- pik3cb
- pik3r1
- pik3r2
- plcg1
- sb:eu508
- sb:eu615
- si:ch211-147g19.3
- sos1
- src
- stat1
- stat1a
- stat5
- stat5.1
- stat5.2
- stat5a
- stat5b
- stat6
- stat7
- wu:fa55g05
- wu:fb18e12
- wu:fb34e06
- wu:fb34h10
- wu:fb65b05
- wu:fc05a01
- wu:fc32c12
- wu:fc54a04
- wu:fd20h08
- wu:fi19g05
- wu:fj46f04
- wu:fj57a05
- wu:fj59e07
- wu:fj60e01
- wu:fj66g07
- zgc:100936
- zgc:103549
- zgc:110734
- zgc:153249
- zgc:158274
- zgc:63469
- zgc:73077
- zgc:92024
|
|
RHOQ GTPase cycle
|
|
|
- CAV1
- IQGAP1
- IQGAP3
- LOC100004299
- arhgap1
- arhgap35a
- arhgap5
- arl13b
- arl2l1
- cav1
- cb422
- cb80
- cdc42
- cdc42a
- cdc42ep2
- cdc42ep3
- cdc42ep4
- cdc42ep4a
- cftr
- cip4
- cx43
- dlg3
- fb55a05
- fe38f01
- fj62g06
- fk03b12
- fk61c06
- gja1
- gopc
- hmp
- im:7152854
- im:7156663
- iqgap1
- iqgap3
- jup
- jupa
- kinase
- llk
- mpp7
- pak2
- pak2a
- rab-7
- rab7
- rab7a
- rhoq
- scrb1
- scrib
- shf
- si:dz198m22.1
- slc1a5
- sof
- srgap2
- stb2
- stoml3
- stoml3a
- stoml3b
- tfr1a
- trip10
- vamp3
- vangl1
- wasla
- wu:cegs2891
- wu:fb07d08
- wu:fb55a05
- wu:fb71h01
- wu:fc07c04
- wu:fe38f01
- wu:fi15a09
- wu:fj62g06
- wu:fk03b12
- wu:fk61c06
- zgc:103557
- zgc:110200
- zgc:110361
- zgc:158395
- zgc:55997
- zgc:56254
- zgc:63918
- zgc:64058
- zgc:65853
- zgc:86726
- zgc:91798
- zgc:91889
- zgc:92806
|
|
Neurotransmitter clearance
|
|
|
- cbe
- ces2
- ces2a
- im:6908784
- oct1
- si:dkey-38l12.2
- slc22a2
- wu:fc01b11
- zgc:153863
- zgc:64076
|
|
Interaction With Cumulus Cells And The Zona Pellucida
|
|
|
- CHIA
- ZP3
- ZPC
- b4galt1l
- chia.1
- chia.2
- chia.3
- chia.4
- chia.5
- chia.6
- chioIIa
- chioIa
- chioIb
- chit1
- fa55e05
- fe16c11
- fi20d05
- fj87h02
- im:6902904
- si:dkey-202n12.1
- si:dkey-51e6none
- spam1
- wu:fa55e05
- wu:fa55g10
- wu:fb57c11
- wu:fb61c11
- wu:fb66f12
- wu:fd61a02
- wu:fe16c11
- wu:fi13f01
- wu:fi20d05
- wu:fj87h02
- zfZPC
- zgc:114017
- zgc:153827
- zgc:154116
- zgc:158668
- zgc:162961
- zgc:173556
- zgc:55406
- zgc:55941
- zgc:56053
- zgc:63792
- zgc:77889
- zgc:77912
- zp2
- zp2.2
- zp2a
- zp2l1
- zp2l2
- zp2v2
- zp3
- zp3.2
- zp3.3
- zp3a.2
- zp3al
- zp3b
- zp3d.1
- zp3e
- zpb2b
- zpb2c
- zpc1-2
- zpc2
- zpc3
- zpc4a-1
- zpc6
|
|
Synthesis of Dolichyl-phosphate
|
|
|
- dhdds
- dolk
- dolpp1
- mvd
- mvda
- ngbr
- nus1
- srd5a3
- wu:fd56c06
- zgc:101585
- zgc:77088
|
|
Effects of PIP2 hydrolysis
|
|
|
- bZ1P14.9
- fb09d10
- fv43b11
- prkcd
- prkcda
- prkceb
- prkcha
- si:rp71-1p14.9
- trpc6
- trpc6a
- trpc7b
- wu:fb09d10
- wu:fv43b11
- zgc:172124
- zgc:56558
|
|
ARMS-mediated activation
|
|
|
- arms
- crk
- fb34h10
- fc05a01
- fi19g05
- kidins220
- kidins220b
- ngf
- ngfb
- rap1a
- rap1aa
- wu:fb34h10
- wu:fc05a01
- wu:fc54a04
- wu:fc66g06
- wu:fi19g05
- zgc:100936
- zgc:86676
|
|
Phospholipase C-mediated cascade; FGFR4
|
|
|
- dob
- fc89b01
- fgf-1
- fgf-8
- fgf1
- fgf16
- fgf17
- fgf17b
- fgf18
- fgf18a
- fgf2
- fgf20a
- fgf23
- fgf4
- fgf6b
- fgf8
- fgf8a
- fgfr4
- fj46f04
- id:ibd5158
- plcg1
- wu:fb05c08
- wu:fc89b01
- wu:fj46f04
- wu:fj57a05
- zgc:194535
|
|
The canonical retinoid cycle in rods (twilight vision)
|
|
|
- CRALBPb
- RDHA
- RDHB
- cyp4v2
- cyp4v2a
- dhrs9
- im:6901729
- im:7136890
- lrat
- lrata
- rbp1
- rbp1.1
- rbp1b
- rdh1
- rdh10a
- rdh12
- rdh1l
- rdh5
- rho
- rlbp1
- rlbp1b
- rpe65a
- rpepa
- sb:eu611
- si:dkey-102c8.5
- wu:fb64b07
- wu:fd50b03
- wu:fj43a10
- zfo2
- zgc:100825
- zgc:154161
- zgc:73286
- zgc:77766
- zgc:92430
|
|
Platelet degranulation
|
|
|
- ANX V
- CYB5R1
- IGF-1
- IGF-1L
- IGF-1a
- IGF-I
- LOC792613
- MRP
- PAI
- PAI-1
- PAI1
- PLANH1
- TAGLN
- Tbeta11
- VWF
- abcc4
- actbb
- actn2
- actn2b
- ahsg
- ahsg1
- ai39657
- aldoa
- aldoaa
- antivin
- anx
- anx5
- anxa5
- anxa5b
- apoa
- apoa1
- apoa1a
- apool
- app
- appa
- atv
- atv2
- bactin2
- cb1019
- cb223
- cb420
- cb720
- cb73
- cb79
- cb989
- cd163
- cd36
- cd63
- cdc37l1
- cfd
- cfdl
- chid1
- clu
- ctsf
- cuzn
- cxcl-c13d
- cxcl8b.1
- cxcl8b.3
- cyb5r1
- dZ52I16.4
- dia1
- etID32613.12
- f13a1
- f13a1b
- f5
- fa92e03
- fa96h09
- fam3c
- fam49bb
- fb08c07
- fb11g09
- fb52d02
- fb61f12
- fb63c02
- fc21c08
- fc21h08
- fe38b03
- fi27b02
- figf
- fj34a12
- fj40h03
- fo83d04
- gas6
- hm:zeh0062
- hm:zehn2160
- igf1
- igf2
- igf2a
- igf2b
- ik:tdsubc_2b12
- il8l1
- im:6902790
- im:6909481
- im:7044540
- im:7144020
- ino80e
- itga2b
- itgb3.1
- itgb3b
- itih3a
- itih3a.1
- lft1
- lft2
- lgals3bp
- lgals3bpa
- lhfpl2a
- mage
- manf
- ndnl2
- ola1
- pdgfab
- pdgfbb
- plek
- pros1
- sb:cb420
- sb:cb79
- sccpdha
- sccpdha.1
- scg3
- selp
- sepp1a
- serpine1
- serpinf2b
- si:busm1-52i16.4
- si:bz20i5.3
- si:ch1073-474e24.1
- si:ch211-133n4.4
- si:ch211-138a11.1
- si:ch211-165i18.2
- si:ch211-186e20.7
- si:ch211-229i10.3
- si:ch211-260g14.4
- si:ch211-284e20.8
- si:ch73-54f23.2
- si:dkey-243k1.3
- si:dkey-27b3.6
- si:dkey-46g23.4
- si:dkeyp-105g12.2
- si:dz202l16.5
- si:dz52i16.4
- sm22[a]
- sod1
- sparc
- stxbp2
- sytl4
- tagln2
- tagln3
- tex264a
- tgfb1
- tgfb1a
- tgfb2
- tgfb3
- timp2
- timp2a
- timp2b
- timp2l
- tmsb4x
- tmx3b
- tor4a
- vcl
- vcla
- vegf
- vegf-d
- vegfa
- vegfaa
- vegfc
- vegfd
- vti1b
- vwf
- wu:fa28b10
- wu:fa92e03
- wu:fa96h09
- wu:fa98f06
- wu:fb08c07
- wu:fb10b11
- wu:fb11g09
- wu:fb13a07
- wu:fb13e02
- wu:fb15h03
- wu:fb16b08
- wu:fb52d02
- wu:fb61f12
- wu:fb63c02
- wu:fb63g02
- wu:fc21c08
- wu:fc21h08
- wu:fc32c12
- wu:fc34h12
- wu:fc78g09
- wu:fd21h06
- wu:fd44c03
- wu:fe38b03
- wu:fi27b02
- wu:fj08a12
- wu:fj10f10
- wu:fj34a12
- wu:fj34d10
- wu:fj40h03
- wu:fk65e12
- wu:fo83d04
- xx:ai39657
- xx:tdsubc_2b12
- zgc:101850
- zgc:103687
- zgc:109940
- zgc:123223
- zgc:136726
- zgc:153093
- zgc:153249
- zgc:153327
- zgc:153334
- zgc:153988
- zgc:154001
- zgc:158410
- zgc:171446
- zgc:172339
- zgc:195198
- zgc:56042
- zgc:63525
- zgc:63860
- zgc:65825
- zgc:65967
- zgc:66013
- zgc:73352
- zgc:77709
- zgc:85740
- zgc:85799
- zgc:85807
- zgc:92058
- zgc:92376
- zgc:92513
- zgc:92525
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