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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | K99 | unnamed ligand | Oligosaccharides | NeuGc(a2-3)Gal(b1-4)Glc | Binding | 2885220 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuGc3-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Escherichia coli | K99 | GD1a(NeuGc) | Disialoglycosphingolipids | NeuGc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7849044 | |
| Rotavirus | Unknown | GD1a(NeuGc) | Disialoglycosphingolipids | NeuGc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Rotavirus | Unknown | GD1a(NeuGc/NeuAc) | Disialoglycosphingolipids | NeuGc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Rotavirus | Unknown | GD1a(NeuGc/NeuAc) | Disialoglycosphingolipids | NeuGc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Equine rhinitis A virus | Viral protein | NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc/GlcNAc/(GlcNAc)n | Binding | 15302947 |
| Influenza virus | Unknown | GT3 | Trisialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Escherichia coli | F1C | Disialosyl lacto-N-nor-hexaosylceramide (DSnHC) | Sialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)[Gal(b1-4)GlcNAc]2(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | Human erythrocytes | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Vibrio cholerae | Cholera toxin | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Tetanus toxin | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | F1C | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Escherichia coli | Unknown | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Clostridium tetani | Unknown | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Influenza virus | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 1740131 | |
| Escherichia coli | K99-fimbriae | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Lactobacillus casei | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | Intestinal tract | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 8912650 |
| Escherichia coli | PsaA/B (pH-6 antigen) | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Vibrio cholerae | Cholera toxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 |
