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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | Hia | unknown carbohydrate ligand | Saccharides | Human conjunctival cells (respiratory tract) | Binding | 10341176 | |
| Escherichia coli | P-pili | Surfactant-like particles (SLP) | Non-glycosylated Lipids | Human colonocytes and enterocytes | Binding | 10531281 | |
| Escherichia coli | PapD-PapG (class I) | Surfactant-like particles (SLP) | Non-glycosylated Lipids | Human colonocytes and enterocytes | Binding | 10531281 | |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Human immunodeficiency virus | Unknown | Galactosylceramide (or derivative) | Monoglycosylceramides | Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 1378511 |
| Escherichia coli | 20K-fimbriae | GlcNAc sequence | Saccharides | Human colon carcinoma Caco-2 cell line | GlcNAc | Binding | 8557360 |
| Mycoplasma pneumoniae | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | GD1a | Disialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(3SO4)(b1-3)-alkylacylglycerol | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | GM3(NeuGc) | Monosialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Galactosylceramide 6-sulfate | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(6SO4)(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Galactosyl sulfatide | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(3SO4)(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Sulfated glucuronyl paragloboside | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | GlcA(3SO4)(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Glucosylceramide | Monoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | I-active Lactoisooctaosylceramide | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)GlcNAc(b1-6)[Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
