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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▼ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Klebsiella pneumoniae | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Salmonella spp. | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Pseudomonas aeruginosa | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Serratia marcescens | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Shigella flexneri | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Escherichia coli | Type 1-fimbriae | trisaccharide: Man(a1-3)Man(b1-4)GlcNAc | Oligosaccharides | Man(a1-3)Man(b1-4)GlcNAc | Binding | 16564136 | |
| Escherichia coli | Type 1-fimbriae | β-D-glycosides | Glycoconjugates | Patient with urinary tract infection | Binding | 6138149 | |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | unnamed ligand | Oligosaccharides | Urine | Man(a1-3)Man(a1-6)Man | Binding | 16564136 |
| Escherichia coli | Type 1-fimbriae | Glycoside p-nitrophenyl alpha-D-mannopyranoside | Glycoconjugates | Patient with urinary tract infection | Binding | 6138149 | |
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | N-Acetylgalactosamine | Monosaccharides | Intestinal cells | GalNAc | Binding | 15322032 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | Galactose | Monosaccharides | Intestinal cells | Gal | Binding | 15322032 |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Treponema pallidum | Tp38 (TpMglB-2) lipoproteins | Glucose | Monosaccharides | Glc | Binding | 15060032 | |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | Toxin A | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium tetani | Tetanus toxin (Hc fragment) | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
| Clostridium tetani | Tetanus toxin (C-fragment) | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 | |
| Clostridium tetani | Tetanus toxin | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
| Clostridium tetani | Tetanus toxin | GT1b | Trisialoglycosphingolipids | Brain membrane | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
