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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | PsaA/B (pH-6 antigen) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7721812 | |
| Vibrio cholerae | Cholera toxin | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Rotavirus | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Escherichia coli | (class III) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7721812 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Escherichia coli | F1C | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Cytomegalovirus | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9780061 | |
| Escherichia coli | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Actinomyces viscosus | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Mycoplasma pneumoniae | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Escherichia coli | F1C | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) (t18:0-h20:0-h24:0) | Oligoglycosylceramides | Human kidney tissues | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Escherichia coli | F1C | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) (d18:1-16:0/24:0) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | PapG (class I) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Streptococcus suis | Adhesins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Pseudomonas aeruginosa | Type 4-pili | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Epithelial cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | Shiga toxin (Stx2) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Vero cells | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15292153 |
| Escherichia coli | PapG (class II) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
