PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species ▼ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Helicobacter pylori | Unknown | unnamed ligand | Oligosaccharides | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]Gal | Binding | 16564136 | |
Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group B-Lewis b (BLeb) antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A-Lewis b (ALeb) antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 15273394 | |
Helicobacter pylori | Adhesins | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Binding | 12628483 | ||
Helicobacter pylori | Unknown | Ganglio glycolipids | Glycosphingolipids | Binding | 16088272 | ||
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | Human erythrocytes | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GM2(NeuAc) | Monosialoglycosphingolipids | Human brain | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | Human meconium | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialylparagloboside(NeuGc) | Monosialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl Lewis a (SLea) (GSL) | Monosialoglycosphingolipids | Human bile bladder tumor | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Bovine erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Bovine buttermilk | Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | I-active ganglioside | Sialoglycosphingolipids | Human placenta | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuGc3-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | Rabbit thymus | NeuGc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | Piglet intestine | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse small intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
Helicobacter pylori | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9169796 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
GlyCosmos Portal v4.0.0
Last updated: August 19, 2024