PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Clostridium botulinum | Unknown | Lactose | Disaccharides | Intestine-407 cells | Gal(b1-4)Glc | Binding | 15850798 |
Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
Escherichia coli | S-fimbriae (SfaA) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Brain endothelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 8098039 |
Pseudomonas aeruginosa | Type 4-pili | Lactosylceramide (Lactocerebroside) | Diosylceramides | Epithelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
Bordetella pertussis | Pertussis toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
Saccharomyces cerevisiae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
Propionibacterium granulosum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
Sporothrix schenckii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
Candida albicans | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
Bordetella pertussis | FHA (1141-1279) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Ciliated epithelium of the respiratory tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 11348687 |
Histoplasma capsulatum | Adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Phagocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 19547878 |
Bordetella pertussis | PT (subunit S2 of B oligomer) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gonorrhoeae patients | Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
Actinomyces viscosus | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
Mycoplasma pneumoniae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
Lactobacillus johnsonii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
Histoplasma capsulatum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
Propionibacterium freudenreichii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes, Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
Cryptococcus neoformans | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
Lactobacillus casei | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Intestinal tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
Actinomyces naeslundii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
Helicobacter pylori | Phe147 in HpaA (Helicobacter pylori adhesin A) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 16953581 | |
Helicobacter bilis | Lectin-hemagglutinin adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
Helicobacter pylori | Lectin-hemagglutinin adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 |
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Last updated: August 19, 2024