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Glycan Structure Repository
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Glycoconjugate Repository
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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Bordetella pertussis | Iron-induced surface-exposed proteins | Sialic acid | Monosaccharides | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Plasmodium falciparum | Unknown | Sialic acid | Monosaccharides | Glycophorins A/B on the erythrocyte membrane | Binding | 3308959 | |
| Rotavirus | Unknown | Sialic acid | Monosaccharides | MA-104 cells | Binding | 10659372 | |
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Epithelial cells of small intestine | Binding | 16511112 | |
| Influenza virus | Unknown | Neuraminic acid | Monosaccharides | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Newcastle disease virus | HN(hemagglutinin-neuraminidase) glycoproteins | Sialic acid | Monosaccharides | Binding | 17205603 | ||
| Sendai virus | "HN (hemagglutinin neuraminidase), F (fusion protein)" | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Rotavirus | VP8 (galectin) | Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me)) | Monosaccharides | Binding | 17306299 | ||
| Rotavirus | VP8 (spike protein) | Sialic acid | Monosaccharides | Binding | 17277447 | ||
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Binding | 18540062 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 16088272 | ||
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
| Clostridium botulinum | HA | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Pseudomonas aeruginosa | PA-IIL | L-Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Not Binding | 14729696 | |
| Pseudomonas aeruginosa | LecB | alpha-methyl-fucoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Pseudomonas aeruginosa | LecA | Alpha-methyl-galactoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
