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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Escherichia coli | 18-kDa fimbrial adhesin | Galactose derivatives | Saccharides | HEp-2 cells | Gal | Binding | 11368522 |
| Shigella dysenteriae | Adhesins | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11381327 | |
| Shigella dysenteriae | Adhesins | Colonic mucin | Glycoproteins | Colon | Binding | 11381327 | |
| Shigella dysenteriae | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11381327 | |
| Shigella dysenteriae | Adhesins | Lipid extracts of Hep-2 cells | Non-glycosylated Lipids | HEp-2 cells | Binding | 11381327 | |
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Basic fibroblast growth factor (bFGF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Basic fibroblast growth factor (bFGF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | von Willebrand factor (VWF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | von Willebrand factor (VWF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Escherichia coli | F1C | β-GalNac-1,4-β-Gal-containing structures | Saccharides | GalNAc(b1-4)Gal(b | Binding | 11401961 | |
| Escherichia coli | S-fimbriae | α-Sialyl-2,3-lactose-containing receptors | Saccharides | Binding | 11401961 | ||
| Escherichia coli | S-fimbriae | unnamed ligand | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 11454740 | |
| Escherichia coli | PapG (class III) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | P-pili | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | P-pili | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | PapG (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Hepatitis virus | Unknown | N-linked glycans | N-glycans | Binding | 11530212 | ||
| Trypanosoma cruzi | CBPs (carbohydrate-binding proteins) | High mannose glycans containig the Manα1-2Manα1-6Manα1-6 structure | Saccharides | Man(a1-2)Man(a1-6)Man(a1-6) | Binding | 11555616 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Paramyxovirus | Unknown | 116 kDa glycoprotein (containing sialic acid residues with N-linked glycans) | N-glycans | Neurones of all brain regions | Binding | 11666031 | |
| Escherichia coli | F1C | Lactosylceramide (t18:0-h16:0-h24:0) | Diosylceramides | Rabbit small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Escherichia coli | F1C | Galactosylceramide (t18:0-h22:0-h24:0) | Monoglycosylceramides | Human kidney | Gal(b1-1)Cer | Binding | 11877427 |
