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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | Neural cell lines | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 16564136 |
| Human immunodeficiency virus | HIV surface glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural cell lines | Gal(b1-1)Cer | Binding | 1857969 |
| Streptococcus agalactiae | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Neonatal meningitis | Binding | 11007786 | |
| Streptococcus pneumoniae | PsaA (Lary family) | unknown carbohydrate ligand | Saccharides | Nasopharynx, Alveolar epithelial cells | Binding | 10341176 | |
| Polyoma virus | Unknown | unnamed ligand | Oligosaccharides | Murine small plaque | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc | Binding | 8574698 |
| Histoplasma capsulatum | Lectin-like component | Galactosylated surface molecules (mainly β-anomer) | Glycoconjugates | Murine macrophages | Binding | 19547878 | |
| Reovirus | sigma 1 proteins | Sialic acid | Monosaccharides | Murine intestine, Murine spleen, Murine liver, Murine brain, Human cholangiocarcinoma cells | Binding | 12813018 | |
| Mycoplasma pneumoniae | Adhesins | Laminin | Glycoproteins | Murine Engelbreth Holm Swarm tumor, Murine erythrocytes | Binding | 2470754 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Mucosal surface of the gastric epithelium | Binding | 12640357 | |
| Neisseria gonorrhoeae | 36-kDa proteins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Neisseria gonorrhoeae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Neisseria gonorrhoeae | 36-kDa proteins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Neisseria gonorrhoeae | Adhesins | unnamed ligand | Oligosaccharides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc | Binding | 2115881 |
| Neisseria gonorrhoeae | 18-kDa proteins | unnamed ligand | Oligosaccharides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc | Binding | 2115881 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse small intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Lactobacillus johnsonii | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse small intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GgO4 (de-N-acylated) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Actinomyces viscosus | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Shigella dysenteriae | B subunit | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Mouse small intestine | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse small intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Lactobacillus johnsonii | Unknown | Sulfo-gangliotetraosylceramide (Sulfo-GgO4) | Sulfoglycosphingolipids | Mouse small intestine | HSO3(-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces viscosus | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse large intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse large intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
