GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **128** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Calnexin/calreticulin cycle	Calnexin Calreticulin Protein disulfide-isomerase 2	Q23858 Q54EN4 Q55BA8	cnxA crtA pdi2	Dictyostelium discoideum
RAF activation	Kinase and exchange factor for Rac B Probable serine/threonine-protein kinase DDB_G0267566 Probable serine/threonine-protein kinase DDB_G0267686 Probable serine/threonine-protein kinase DDB_G0268876 Probable serine/threonine-protein kinase DDB_G0272092 Probable serine/threonine-protein kinase DDB_G0282963 Probable serine/threonine-protein kinase DDB_G0291516 Probable serine/threonine-protein kinase DDB_G0291664 Probable serine/threonine-protein kinase MARK-C Probable tyrosine-protein kinase DDB_G0290471 Serine/threonine-protein kinase phg2 Stress-activated protein kinase alpha	Q1ZXR2 Q54C71 Q54EG9 Q54EM1 Q54G28 Q54QQ1 Q54RR9 Q54TA3 Q55A55 Q55EI8 Q55GG4 Q86AT8	DDB_G0267566 DDB_G0267686 DDB_G0268876 DDB_G0272092 DDB_G0282963 DDB_G0290471 DDB_G0291516 DDB_G0291664 RacGEF kxcB mrkC phg2 spkA-1 spkA-2	Dictyostelium discoideum
GDP-fucose biosynthesis	Fucokinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-fucose transporter 1 GDP-mannose 4,6 dehydratase	Q1ZXF7 Q54NH4 Q550W6 Q55C77 Q55DE9	DDB_G0269678 fpgt fuct1 ger gmd slc35c1	Dictyostelium discoideum	G85196CF
Synthesis of glycosylphosphatidylinositol (GPI)	GPI ethanolamine phosphate transferase 1 GPI mannosyltransferase 1 GPI mannosyltransferase 2 Mannosyltransferase Mannosyltransferase Phosphatidylinositol glycan, class F Phosphatidylinositol glycan, class X Phosphatidylinositol-glycan biosynthesis class W protein Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Transmembrane protein	Q1ZXB4 Q54C64 Q54IA4 Q54MC0 Q54PB0 Q54PM5 Q54QP2 Q54UQ5 Q54WY9 Q551Y7	DDB_G0276251 DDB_G0280891 pigB pigF pigN pigX pigl pigm pigw smp3	Dictyostelium discoideum
Glycerophospholipid biosynthesis	Copine-A Copine-B Copine-C Copine-D Copine-E Copine-F Sphingosine kinase A Sphingosine kinase B Sphingosine kinase related protein Sphingosine kinase related protein	Q1ZXB3 Q54FY7 Q54HN2 Q54P51 Q55GG1 Q6B516 Q75JX1 Q7YXU4 Q86K21 Q86KF9	SK SPHK cpnA cpnB-1 cpnB-2 cpnC cpnD cpnE cpnF sgkA sgkB sgkC sgkD	Dictyostelium discoideum
Receptor Mediated Mitophagy	Autophagy protein 5 Autophagy-related protein 8-like protein DDB_G0290491 Autophagy-related protein 8 Casein kinase II subunit alpha Casein kinase II subunit beta Probable serine/threonine-protein kinase DDB_G0286481 Serine/threonine-protein kinase atg1 Transmembrane protein Ubiquitin-like protein atg12	Q02720 Q54G11 Q54GT9 Q54LR6 Q54PF1 Q75K07 Q86CR6 Q86CR8 Q86CS2	DDB_G0277699 DDB_G0286481 DDB_G0290491 apg1 apg12 apg5 apg8 atg1 atg12 atg5 atg8 casK csnk2b	Dictyostelium discoideum
Regulation of TP53 Activity through Phosphorylation	Casein kinase II subunit alpha Casein kinase II subunit beta FACT complex subunit SPT16 FACT complex subunit SSRP1 Probable serine/threonine-protein kinase DDB_G0286481 Probable serine/threonine-protein kinase atr1 Probable serine/threonine-protein kinase dyrk2	Q02720 Q54BC9 Q54ER4 Q54G78 Q54LR6 Q54PF1 Q54S43	DDB_G0286481 atr1 casK csnk2b dyrk2 spt16 ssrp ssrp1	Dictyostelium discoideum
Condensation of Prometaphase Chromosomes	Casein kinase II subunit alpha Casein kinase II subunit beta Condensin complex subunit 2 Condensin-2 complex subunit D3 Nuclear condensin complex subunit 3 C-terminal domain-containing protein Probable serine/threonine-protein kinase DDB_G0286481 Structural maintenance of chromosomes protein 2	Q02720 Q54B17 Q54DR4 Q54LR6 Q54PF1 Q54PK4 Q54TZ8	DDB_G0281419 DDB_G0286481 DDB_G0292066 DDB_G0293984 casK csnk2b smc2	Dictyostelium discoideum
Mitochondrial ABC transporters	ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 5 ABC transporter B family member 6 ABC transporter B family member 7 Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD	P54683 Q23868 Q54BT3 Q54RU1 Q55DA7 Q8T9W1 Q8T9W2 Q8T9W4 Q9GTN7	abcB2 abcB3 abcB5 abcB6 abcB7 tagA tagB tagC tagD	Dictyostelium discoideum
Prednisone ADME	ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 Aldose reductase A Aldose reductase B Aldose reductase C Glycosyl transferase family 28 C-terminal domain-containing protein Glycosyltransferase family 28 N-terminal domain-containing protein Glycosyltransferase family 28 N-terminal domain-containing protein NADP-dependent oxidoreductase domain-containing protein Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD	P54683 Q23868 Q54BT3 Q54NZ7 Q54RU1 Q55DA7 Q55FB2 Q55FL2 Q55FL3 Q55FX8 Q55FY0 Q6IMN8 Q8T9W1 Q8T9W4 Q9GTN7	DDB_G0268184 DDB_G0268562 abcB2 abcB3 abcB6 abcB7 alrA alrB alrC tagA tagB tagC tagD ugt2 ugt3	Dictyostelium discoideum
Recycling of bile acids and salts	ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 ABC transporter C family member 10 ABC transporter C family member 12 ABC transporter C family member 3 ABC transporter C family member 5 ABC transporter C family member 8 Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD	P54683 Q23868 Q54BT3 Q54JR2 Q54LE6 Q54P13 Q54RU1 Q54U44 Q55DA7 Q8ST87 Q8T9W1 Q8T9W4 Q9GTN7	abcB2 abcB3 abcB6 abcB7 abcC10 abcC12 abcC3 abcC5 abcC8 tagA tagB tagC tagD	Dictyostelium discoideum
Atorvastatin ADME	ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 ABC transporter C family member 10 ABC transporter C family member 12 ABC transporter C family member 3 ABC transporter C family member 5 ABC transporter C family member 8 Glycosyl transferase family 28 C-terminal domain-containing protein Glycosyltransferase family 28 N-terminal domain-containing protein Glycosyltransferase family 28 N-terminal domain-containing protein Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD	P54683 Q23868 Q54BT3 Q54JR2 Q54LE6 Q54P13 Q54RU1 Q54U44 Q55DA7 Q55FB2 Q55FX8 Q55FY0 Q8ST87 Q8T9W1 Q8T9W4 Q9GTN7	DDB_G0268184 abcB2 abcB3 abcB6 abcB7 abcC10 abcC12 abcC3 abcC5 abcC8 tagA tagB tagC tagD ugt2 ugt3	Dictyostelium discoideum
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 Aldose reductase A Aldose reductase B Aldose reductase C NADP-dependent oxidoreductase domain-containing protein Peroxisomal acyl-coenzyme A oxidase 1 Probable enoyl-CoA hydratase 2 Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD	P54683 Q23868 Q54BT3 Q54GQ6 Q54NZ7 Q54RU1 Q54XZ0 Q55DA7 Q55FL2 Q55FL3 Q6IMN8 Q8T9W1 Q8T9W4 Q9GTN7	DDB_G0268562 abcB2 abcB3 abcB6 abcB7 acox1 alrA alrB alrC mfe2 mfeB tagA tagB tagC tagD	Dictyostelium discoideum
Ion homeostasis	Calcium-transporting ATPase PAT1 Calcium-transporting ATPase Inositol 1,4,5-trisphosphate receptor-like protein A NADPH--cytochrome P450 reductase	P54678 Q54HG6 Q55CT1 Q9NA13	DDB_G0289473 iplA patA redB	Dictyostelium discoideum
Cargo recognition for clathrin-mediated endocytosis	ABC transporter C family member 13 ABC transporter C family member 14 ABC transporter C family member 15 ABC transporter C family member 1 ABC transporter C family member 2 ABC transporter C family member 6 ABC transporter C family member 7 ABC transporter C family member 9 ANTH domain-containing protein AP-1 complex subunit beta AP-1 complex subunit mu AP-2 complex subunit alpha-2 AP-2 complex subunit mu AP-2 complex subunit sigma ATPase AAA-type core domain-containing protein Autophagy-related protein 27 Autophagy-related protein 27 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7 COP9 signalosome complex subunit 8 Epidermal growth factor receptor substrate 15 homolog Epsin Lysosome membrane protein 2-C MRH domain-containing protein MRH domain-containing protein MRH domain-containing protein NEDD8 Sugar transporter family protein Synaptobrevin-A Synaptobrevin-B Transmembrane protein Ubiquilin	P54672 Q54B82 Q54C92 Q54CZ8 Q54E53 Q54EH1 Q54EK2 Q54GB3 Q54H39 Q54HL6 Q54HS9 Q54K24 Q54KI4 Q54LD2 Q54NL1 Q54PF3 Q54QX3 Q54UC8 Q54V86 Q54VC1 Q54VJ0 Q54WQ8 Q54X82 Q54XB6 Q54XV3 Q54Y50 Q55BD5 Q55FE2 Q55FQ9 Q6TMJ9 Q75K24 Q86KI1 Q86KK4 Q86KL3 Q8T6H3 Q8T6H8 Q9NIF3	DDB_G0268156 DDB_G0274261 DDB_G0279059 DDB_G0279493 DDB_G0281155 DDB_G0286699 DDB_G0292610 abcC1 abcC13 abcC14 abcC15 abcC2 abcC6 abcC7 abcC9 ap1b1 ap2a1-1 ap2a1-2 ap2s1 apm1 apm2 apmA clmA csn1 csn2 csn3 csn4 csn5 csn6 csn7 csn8 epnA eps15 lmpC mrrA nedd8 sonA sybA sybB ubqln	Dictyostelium discoideum
DAG and IP3 signaling	Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P54644 Q54IF2	DDB_G0288795 akt dagA pkbA	Dictyostelium discoideum
Response to elevated platelet cytosolic Ca2+	Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P54644 Q54IF2	DDB_G0288795 akt dagA pkbA	Dictyostelium discoideum
Role of phospholipids in phagocytosis	PA-phosphatase related-family protein DDB_G0271516 PA-phosphatase related-family protein DDB_G0275547 PA-phosphatase related-family protein DDB_G0284367 Phospholipase D A Phospholipase D B Phospholipase D C Phospholipase D Y Phospholipase D Z Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog phospholipase D	P54644 Q54IF2 Q54K50 Q54PR7 Q54Q49 Q54SA1 Q54UK0 Q54WR4 Q54Z25 Q86AF0 Q8MXL9	DDB_G0271516 DDB_G0275547 DDB_G0284155 DDB_G0284367 DDB_G0288795 akt dagA pkbA pld1 pld3 pldA pldB pldC pldY pldZ	Dictyostelium discoideum
RAF/MAP kinase cascade	Extracellular signal-regulated kinase 1	P42525	erk1 erkA	Dictyostelium discoideum
Regulation of HSF1-mediated heat shock response	14-3-3-like protein Extracellular signal-regulated kinase 1 Glycogen synthase kinase-3 Heat shock 70 kDa protein, mitochondrial Heat shock 70-related protein 5 Heat shock cognate 70 kDa protein 1 Heat shock cognate 70 kDa protein 2 Heat shock cognate 70 kDa protein 3 Heat shock cognate 70 kDa protein 4 Heat shock factor-type DNA-binding domain-containing protein Heat shock protein 88 Luminal-binding protein 2 Myb domain-containing protein Protein OPI10 homolog	P36415 P42525 P51136 P54632 Q54BD8 Q54BE0 Q54MR6 Q54TH5 Q54UC1 Q54YL9 Q557E0 Q6TMK3 Q8I0H7 Q8T869	DDB_G0278179 DDB_G0281165 DDB_G0281747 DDB_G0285709 DDB_G0293674 DDB_G0293678 bip2 erk1 erkA fttB gsk3 gskA hsc70 hsp70 hspB hspE-1 hspE-2 hspH mhsp70	Dictyostelium discoideum
G alpha (i) signalling events	Guanine nucleotide-binding protein alpha-9 subunit Guanine nucleotide-binding protein subunit beta Metabotropic glutamate receptor-like protein E Metabotropic glutamate receptor-like protein P Metabotropic glutamate receptor-like protein Q RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein	P36408 Q54ET0 Q54F54 Q54K09 Q54LD1 Q54M81 Q54R41 Q54S99 Q54XJ6 Q556I3 Q55E55	DDB_G0270858 DDB_G0273033 DDB_G0278897 DDB_G0282583 DDB_G0286173 DDB_G0286817 GluPR gpa9 gpaI gpbA grlE grlP grlQ	Dictyostelium discoideum
COPII-mediated vesicle transport	Alpha-soluble NSF attachment protein Ankyrin repeat-containing protein Casein kinase I DDHD domain-containing protein DDHD domain-containing protein DDHD domain-containing protein DDHD domain-containing protein Gamete and mating-type specific protein A Gamma-soluble NSF attachment protein Golgi reassembly stacking protein L-type lectin-like domain-containing protein Protein SEC13 homolog Protein transport protein SEC23 Protein transport protein SEC24 Protein transport protein SEC31 Protein transport protein sec16 Rab GTPase Rab GTPase RabGAP/TBC domain-containing protein Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-1D Ras-related protein RabA Ras-related protein RabF1 Ras-related protein RabS Ras-related protein RabU Ras-related protein RabY Sec1 family domain-containing protein 1 homolog Serine/threonine-protein phosphatase 6 catalytic subunit Small COPII coat GTPase SAR1A Small GTPase Synaptobrevin domain-containing protein Syntaxin-7A Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6B Uncharacterized protein Uncharacterized protein Uncharacterized protein V-SNARE family protein Vesicle tethering protein Uso1/P115-like head domain-containing protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b WD-40 repeat-containing protein cathepsin X t-SNARE coiled-coil homology domain-containing protein t-SNARE family protein	P34139 P34140 P34141 Q54BK5 Q54C46 Q54CU7 Q54DF4 Q54DS8 Q54EA5 Q54EW9 Q54IJ1 Q54J43 Q54JY7 Q54M76 Q54ME1 Q54NP6 Q54NU2 Q54R55 Q54RT5 Q54RV6 Q54SD0 Q54SJ2 Q54SV1 Q54T59 Q54TK7 Q54U61 Q54UU1 Q54YG5 Q54Z72 Q54ZH1 Q552K3 Q553R1 Q555X3 Q556Y4 Q556Z3 Q557G3 Q558I0 Q559R0 Q55BR0 Q55CR0 Q55CT5 Q55DN9 Q55DP0 Q55FD0 Q55FM2 Q75JI3 Q7KWT0 Q86K94 Q86KP6 Q8T2J5 Q9U9A3 Q9U9R7	DDB_G0268044 DDB_G0268452 DDB_G0269584 DDB_G0269942 DDB_G0270566 DDB_G0271968 DDB_G0274803 DDB_G0275331 DDB_G0276935 DDB_G0281693 DDB_G0282433 DDB_G0283055 DDB_G0286167 DDB_G0291694 DDB_G0293712 cak1-1 cak1-2 cnrM ctsZ gmsA grpA nsfA ppp6c pppD rab1A rab1B rab1D rab1E rabA rabF1-1 rabF1-2 rabS rabU rabW rabY rsmM sarA scfd1 sec13 sec23 sec24 sec24l sec31 snpA snpC syn5 syn7 syn7A tmem1-1 tmem1-2 trapcc10-1 trapcc10-2 trappc1-1 trappc1-2 trappc2 trappc2l trappc3 trappc4 trappc5 wimA	Dictyostelium discoideum
Negative regulation of MAPK pathway	BRCA1-associated protein Extracellular signal-regulated kinase 1 Kinase and exchange factor for Rac B MAP kinase phosphatase with leucine-rich repeats protein 1 MAP kinase phosphatase with leucine-rich repeats protein 2 MAP kinase phosphatase with leucine-rich repeats protein 3 Probable dual specificity protein phosphatase DDB_G0271350 Probable rhodanese domain-containing dual specificity protein phosphatase Probable serine/threonine-protein kinase DDB_G0267566 Probable serine/threonine-protein kinase DDB_G0267686 Probable serine/threonine-protein kinase DDB_G0268876 Probable serine/threonine-protein kinase DDB_G0272092 Probable serine/threonine-protein kinase DDB_G0282963 Probable serine/threonine-protein kinase DDB_G0291516 Probable serine/threonine-protein kinase DDB_G0291664 Probable serine/threonine-protein kinase MARK-C Probable tyrosine-protein kinase DDB_G0290471 Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase Serine/threonine-protein kinase phg2 Stress-activated protein kinase alpha Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase 2 Tyrosine-protein phosphatase 3	P34137 P34138 P42525 P54637 Q1ZXR2 Q54C71 Q54CK7 Q54EG9 Q54EM1 Q54G28 Q54QQ1 Q54RR9 Q54TA3 Q54Y32 Q556Y8 Q55A55 Q55BI8 Q55C68 Q55CS7 Q55CS8 Q55EI8 Q55GG4 Q86AT8 Q8T813	DDB_G0267566 DDB_G0267686 DDB_G0268876 DDB_G0270200 DDB_G0271350 DDB_G0271860 DDB_G0272092 DDB_G0273199 DDB_G0282963 DDB_G0290471 DDB_G0291516 DDB_G0291664 DDB_G0292880 RacGEF erk1 erkA kxcB mpl1 mpl2 mpl3 mrkC phg2 ptp1 ptp2 ptp3 ptpA1-1 ptpA1-2 ptpB ptpC spkA-1 spkA-2	Dictyostelium discoideum
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 3beta-hydroxysteroid dehydrogenase Cycloartenol synthase Delta(14)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl diphosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase B Isopentenyl-diphosphate Delta-isomerase Mevalonate kinase Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Probable acetyl-CoA acetyltransferase Probable lanosterol 14-alpha demethylase Protein arv1 homolog Putative methylsterol monooxygenase DDB_G0269788 Squalene monooxygenase Squalene synthase	P34135 Q1ZXH9 Q54BK1 Q54BK7 Q54DR1 Q54GD9 Q54PP1 Q54TU9 Q54UH9 Q54YQ9 Q55D54 Q55D85 Q86AD9 Q86AG7 Q86HL5 Q9NH02 Q9NH03	DDB_G0269788 DDB_G0271544 DDB_G0281069 DDB_G0281487 Dipi arv1 cas1 cyp51 erg24 fdfT fps ggps1 hgsB hmgA idi ipi mvd mvk sqle	Dictyostelium discoideum
Effects of PIP2 hydrolysis	Diacylglycerol kinase A Inositol 1,4,5-trisphosphate receptor-like protein A Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P34125 P54644 Q54IF2 Q9NA13	DDB_G0288795 akt dagA dgkA iplA mhcK pkbA	Dictyostelium discoideum

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