GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **128** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Metal ion SLC transporters	Copper transport protein Metal transporter nramp1 homolog Probable zinc transporter protein DDB_G0282067	Q54N27 Q54T06 Q869V1	DDB_G0282067 DDB_G0285545 nramp nramp1 slc11a1	Dictyostelium discoideum
Synthesis of PA	Counting factor 60 DDHD domain-containing protein DDHD domain-containing protein DDHD domain-containing protein DDHD domain-containing protein Mitochondrial cardiolipin hydrolase Phospholipase D A Phospholipase D B Phospholipase D C Phospholipid/glycerol acyltransferase domain-containing protein Phospholipid/glycerol acyltransferase domain-containing protein Phospholipid/glycerol acyltransferase domain-containing protein Phospholipid/glycerol acyltransferase domain-containing protein Probable acid phosphatase DDB_G0284753 Probable acid phosphatase DDB_G0284755 Probable glycerol-3-phosphate dehydrogenase, mitochondrial phospholipase D	Q54EA5 Q54EU4 Q54IT8 Q54P71 Q54P72 Q54PR9 Q54Q49 Q54QC1 Q54TK6 Q54UK0 Q54WR4 Q54Z25 Q554U0 Q55CZ2 Q55DN9 Q55DP0 Q86KP6	DDB_G0269584 DDB_G0269848 DDB_G0270566 DDB_G0274969 DDB_G0276935 DDB_G0281695 DDB_G0283951 DDB_G0284155 DDB_G0284753 DDB_G0284755 DDB_G0288523 DDB_G0291332 DDB_G0291694 cf60 pld1 pldA pldB pldC	Dictyostelium discoideum
Degradation of the extracellular matrix	Counting factor associated protein D Cysteine proteinase 2 Cysteine proteinase 3 Cysteine proteinase 4 Cysteine proteinase 5 Cysteine proteinase 6 Cysteine proteinase 7 Uncharacterized protein Uncharacterized protein Uncharacterized protein	P04989 P54639 P54640 Q23894 Q54RQ2 Q54TR1 Q54Y60 Q7KWP5 Q94503 Q94504	CP2 CP3 CP4 CP5 CP6 CP7 DDB_G0272742 DDB_G0278401 DDB_G0282991 cfaD cprB cprC cprD cprE cprF cprG	Dictyostelium discoideum
Cyclin D associated events in G1	Cullin-2 Cyclin-dependent kinases regulatory subunit EF-hand domain-containing protein Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Protein phosphatase 2A scaffold subunit Retinoblastoma-like protein A SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Serine/threonine-protein phosphatase 2A catalytic subunit A Serine/threonine-protein phosphatase 2A regulatory subunit phr2AB Transcription factor E2F/dimerisation partner family protein Transcription factor E2F/dimerisation partner family protein Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	B0G102 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P52285 Q54CI0 Q54FX2 Q54Q23 Q54Q99 Q54QR9 Q54W95 Q557E4 Q7KWP1 Q9XZE5 Q9XZJ3	DDB_G0279813 E2F PP2A PP2Ac Rb cks1 cul2 culB fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 pho2a phr2aB pppA pppD rblA rcdB skp1A skp1B tfdp2 ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116 veg124	Dictyostelium discoideum
Amino acids regulate mTORC1	DEP domain-containing protein DDB_G0279099 Folliculin GATOR2 complex protein MIOS GATOR2 complex protein WDR24 GTP-binding protein Rheb homolog Kaptin NPR2 family protein Protein LST8 homolog Protein SEC13 homolog Protein raptor homolog Ragulator complex protein LAMTOR3 homolog Ragulator complex protein LAMTOR4 homolog Ragulator complex protein LAMTOR5 homolog Ras-related GTP-binding protein A Ras-related GTP-binding protein Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase tor Sestrin homolog UDENN FNIP1/2-type domain-containing protein UPF0171 family protein Uncharacterized protein DDB_G0292160 Uncharacterized protein Uncharacterized protein Uncharacterized protein V-ATPase proteolipid subunit C-like domain-containing protein V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit d VWFA domain-containing protein Vacuolar proton translocating ATPase 100 kDa subunit WD repeat-containing protein DDB_G0292056	O00780 P54641 P54642 P54647 P54648 Q1ZXA8 Q54D08 Q54DS4 Q54DS8 Q54DY3 Q54E04 Q54F59 Q54HT9 Q54IK1 Q54JS5 Q54NW3 Q54PK6 Q54QW5 Q54UF2 Q54UN5 Q54WU6 Q54XA2 Q54Y15 Q54Z13 Q550Q4 Q551B5 Q55AH5 Q55BD9 Q55BR7 Q55DE8 Q76NU1 Q86A77 Q86AS7 Q86C65 Q86IH5 Q86J23 Q86K39 Q8MML6	DDB_G0269680 DDB_G0271288 DDB_G0272696 DDB_G0274141 DDB_G0274833 DDB_G0277257 DDB_G0278475 DDB_G0279099 DDB_G0279427 DDB_G0280947 DDB_G0281111 DDB_G0283567 DDB_G0284957 DDB_G0289243 DDB_G0291948 DDB_G0292056 DDB_G0292160 atp6v1d atp6v1g dvacB lst8 mapbpip mios ragA ragC raptor rheb sec13 tor vatA vatB vatC vatD-1 vatD-2 vatE vatF vatH vatM vatP vatg wdr24	Dictyostelium discoideum
Switching of origins to a post-replicative state	DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM7 DNA replication licensing factor mcm5 DNA replication licensing factor mcm6	Q54CP4 Q54LI2 Q54RU0 Q54VI9 Q86B14 Q86IF1	MCM7 mcm2 mcm3 mcm4 mcm5 mcm6 mcm7	Dictyostelium discoideum
Effects of PIP2 hydrolysis	Diacylglycerol kinase A Inositol 1,4,5-trisphosphate receptor-like protein A Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog	P34125 P54644 Q54IF2 Q9NA13	DDB_G0288795 akt dagA dgkA iplA mhcK pkbA	Dictyostelium discoideum
Synthesis of dolichyl-phosphate-glucose	Dolichyl-phosphate beta-glucosyltransferase	Q54J42	alg5 dgtA	Dictyostelium discoideum
Regulation of necroptotic cell death	Dual specificity protein kinase splA Dual specificity protein kinase splB Dual specificity protein kinase zak2 Dual specificity protein kinase zakA Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable E3 ubiquitin-protein ligase rbrA Probable serine/threonine-protein kinase DDB_G0267514 Probable serine/threonine-protein kinase DDB_G0272254 Probable serine/threonine-protein kinase DDB_G0288147 Probable serine/threonine-protein kinase drkA Probable serine/threonine-protein kinase drkB Probable serine/threonine-protein kinase drkC Probable serine/threonine-protein kinase qkgA Probable serine/threonine-protein kinase roco11 Probable serine/threonine-protein kinase roco4 Probable serine/threonine-protein kinase roco5 Probable serine/threonine-protein kinase roco7 Probable serine/threonine-protein kinase roco8 RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase RBR-type E3 ubiquitin transferase Seven transmembrane domain-containing tyrosine-protein kinase 1 UBC core domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P18160 P18161 Q1ZXD6 Q54CI0 Q54H45 Q54H46 Q54I29 Q54IL3 Q54JC7 Q54M77 Q54N73 Q54TA1 Q54XG4 Q54YU7 Q552C6 Q55A09 Q55GE6 Q55GU0 Q6T486 Q6XHA5 Q6XHB2 Q75JK0 Q8SSS9 Q8T2Q2	7tmk1 DDB_G0267514 DDB_G0272254 DDB_G0275145 DDB_G0278075 DDB_G0278981 DDB_G0288147 DDB_G0288683 DDB_G0289043 DpyK1 DpyK2 DpyK4 drkA drkB drkC pyK1 pyk2 pyk4 pykA pykB qkgA-1 qkgA-2 rbrA rk1 rk2 rk3 roco11 roco2-1 roco2-2 roco4 roco5 roco7 roco8 splA splB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116 vsk1 zak1 zak2 zakA	Dictyostelium discoideum
Glycolysis	Enolase A Enolase B Fructose-bisphosphate aldolase Glucosamine-6-phosphate isomerase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoglycerate kinase Probable phosphoglucomutase-2 Probable phosphoglycerate mutase Pyruvate kinase Triosephosphate isomerase Uncharacterized protein	Q54K22 Q54NE6 Q54RF5 Q54RK5 Q54UQ2 Q54XK9 Q55F83 Q5V9E9 Q869R8 Q86A67 Q94469 Q9GPM4	enoA enoB fba g6pi glk gniA gnpda1 gpdA gpi gpmA nagB2 pgam pgi pgkA pgmB pyk tpiA	Dictyostelium discoideum	G58161NS
RAF/MAP kinase cascade	Extracellular signal-regulated kinase 1	P42525	erk1 erkA	Dictyostelium discoideum
GDP-fucose biosynthesis	Fucokinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-fucose transporter 1 GDP-mannose 4,6 dehydratase	Q1ZXF7 Q54NH4 Q550W6 Q55C77 Q55DE9	DDB_G0269678 fpgt fuct1 ger gmd slc35c1	Dictyostelium discoideum	G85196CF
Lewis blood group biosynthesis	Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase WD40 repeat-containing protein	Q54BB7 Q54L56 Q54P60 Q54PH9 Q54PJ9 Q54PK0 Q54PK3 Q54RA6 Q55C63 Q55FA8 Q86J24	DDB_G0270208 fut1 fut10 fut11 fut2 fut3 fut4 fut5 fut6 fut7 fut9	Dictyostelium discoideum	G81971FM G90387AM G98173LG
Synthesis of glycosylphosphatidylinositol (GPI)	GPI ethanolamine phosphate transferase 1 GPI mannosyltransferase 1 GPI mannosyltransferase 2 Mannosyltransferase Mannosyltransferase Phosphatidylinositol glycan, class F Phosphatidylinositol glycan, class X Phosphatidylinositol-glycan biosynthesis class W protein Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Transmembrane protein	Q1ZXB4 Q54C64 Q54IA4 Q54MC0 Q54PB0 Q54PM5 Q54QP2 Q54UQ5 Q54WY9 Q551Y7	DDB_G0276251 DDB_G0280891 pigB pigF pigN pigX pigl pigm pigw smp3	Dictyostelium discoideum
Cargo concentration in the ER	Gamete and mating-type specific protein A L-type lectin-like domain-containing protein Protein transport protein SEC23 Protein transport protein SEC24 Small COPII coat GTPase SAR1A Uncharacterized protein V-SNARE family protein Vesicle-trafficking protein SEC22b cathepsin X t-SNARE family protein	Q54ME1 Q54R55 Q54T59 Q54U61 Q54Z72 Q54ZH1 Q559R0 Q55CR0 Q55FD0 Q8T2J5	DDB_G0268452 DDB_G0269942 DDB_G0271968 ctsZ gmsA sarA sec23 sec24 sec24l syn5	Dictyostelium discoideum
Glycogen breakdown (glycogenolysis)	Glycogen debranching enzyme Glycogen phosphorylase 1 Glycogen phosphorylase 2 Maltase Phosphoglucomutase-1 Uncharacterized protein	P34114 Q00766 Q23919 Q54K94 Q54L24 Q55D50	agl gaa glpD glpV gtr3 pgmA	Dictyostelium discoideum	G58161NS
G alpha (i) signalling events	Guanine nucleotide-binding protein alpha-9 subunit Guanine nucleotide-binding protein subunit beta Metabotropic glutamate receptor-like protein E Metabotropic glutamate receptor-like protein P Metabotropic glutamate receptor-like protein Q RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein	P36408 Q54ET0 Q54F54 Q54K09 Q54LD1 Q54M81 Q54R41 Q54S99 Q54XJ6 Q556I3 Q55E55	DDB_G0270858 DDB_G0273033 DDB_G0278897 DDB_G0282583 DDB_G0286173 DDB_G0286817 GluPR gpa9 gpaI gpbA grlE grlP grlQ	Dictyostelium discoideum
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor-like protein A P2X receptor A P2X receptor B P2X receptor C P2X receptor D P2X receptor E	Q54J33 Q54JH4 Q553Y0 Q553Y1 Q86JM7 Q9NA13	iplA p2xA p2xB p2xC p2xD p2xE	Dictyostelium discoideum
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Inositol 1,4,5-trisphosphate receptor-like protein A Ras guanine nucleotide exchange factor P Ras guanine nucleotide exchange factor W Ras-related protein rapA	P18613 Q54TK8 Q55GH9 Q9NA13	gefP gefW iplA rap1 rapA rasGEFP rasGEFW	Dictyostelium discoideum
Sensory perception of sweet, bitter, and umami (glutamate) taste	Inositol 1,4,5-trisphosphate receptor-like protein A	Q9NA13	iplA	Dictyostelium discoideum
RAF activation	Kinase and exchange factor for Rac B Probable serine/threonine-protein kinase DDB_G0267566 Probable serine/threonine-protein kinase DDB_G0267686 Probable serine/threonine-protein kinase DDB_G0268876 Probable serine/threonine-protein kinase DDB_G0272092 Probable serine/threonine-protein kinase DDB_G0282963 Probable serine/threonine-protein kinase DDB_G0291516 Probable serine/threonine-protein kinase DDB_G0291664 Probable serine/threonine-protein kinase MARK-C Probable tyrosine-protein kinase DDB_G0290471 Serine/threonine-protein kinase phg2 Stress-activated protein kinase alpha	Q1ZXR2 Q54C71 Q54EG9 Q54EM1 Q54G28 Q54QQ1 Q54RR9 Q54TA3 Q55A55 Q55EI8 Q55GG4 Q86AT8	DDB_G0267566 DDB_G0267686 DDB_G0268876 DDB_G0272092 DDB_G0282963 DDB_G0290471 DDB_G0291516 DDB_G0291664 RacGEF kxcB mrkC phg2 spkA-1 spkA-2	Dictyostelium discoideum
Acyl chain remodelling of PC	Lysoplasmalogenase homolog Membrane bound O-acyl transferase family protein Patatin family protein Phospholipase B-like protein D	Q54PS7 Q54QX6 Q54XX2 Q86H31	DDB_G0278541 DDB_G0283551 plbD tmem86	Dictyostelium discoideum
Intracellular metabolism of fatty acids regulates insulin secretion	Lysosome membrane protein 2-A Lysosome membrane protein 2-B Lysosome membrane protein 2-C	Q55FQ9 Q9BKJ9 Q9XYS8	lmpA lmpB lmpC	Dictyostelium discoideum
Digestion of dietary carbohydrate	Maltase	Q55D50	gaa	Dictyostelium discoideum	G58161NS G96370VA
Acyl chain remodelling of PE	Membrane bound O-acyl transferase family protein Patatin family protein Phospholipase B-like protein D	Q54PS7 Q54QX6 Q54XX2	DDB_G0278541 DDB_G0283551 plbD	Dictyostelium discoideum

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