GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **601 - 625** of **2090** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Regulation of IFNG signaling	E3 SUMO-protein ligase PIAS1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14543 O15524 O60674 O75925 P01579 P15260 P18031 P23458 P29350 P38484 P63165 Q06124	CIS3 DDXBP1 HCP IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 PIAS1 PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SMT3C SMT3H3 SOCS1 SOCS3 SSI1 SSI3 SUMO1 TIP3 UBL1	Homo sapiens (human)
Regulation of IFNA/IFNB signaling	Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Ubl carboxyl-terminal hydrolase 18	O14543 O15524 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P17181 P18031 P23458 P29350 P29597 P32881 P52630 Q06124 Q9UMW8	CIS3 HCP IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 ISG43 JAK1 JAK1A JAK1B PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT2 TIP3 TYK2 USP18	Homo sapiens (human)
Regulation of HSF1-mediated heat shock response	14-3-3 protein epsilon Active regulator of SIRT1 Aladin BAG family molecular chaperone regulator 1 BAG family molecular chaperone regulator 2 BAG family molecular chaperone regulator 3 BAG family molecular chaperone regulator 4 BAG family molecular chaperone regulator 5 Cell cycle and apoptosis regulator protein 2 DnaJ homolog subfamily B member 1 DnaJ homolog subfamily B member 6 DnaJ homolog subfamily C member 2 DnaJ homolog subfamily C member 7 E3 SUMO-protein ligase RanBP2 Endoplasmic reticulum chaperone BiP Glycogen synthase kinase-3 beta Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 12A Heat shock 70 kDa protein 12B Heat shock 70 kDa protein 13 Heat shock 70 kDa protein 14 Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock 70 kDa protein 4 Heat shock 70 kDa protein 4L Heat shock 70 kDa protein 6 Heat shock cognate 71 kDa protein Heat shock factor protein 1 Heat shock protein 105 kDa Heat shock-related 70 kDa protein 2 Hsc70-interacting protein MAP kinase-activated protein kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NAD-dependent protein deacetylase sirtuin-1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein Hikeshi Protein SEC13 homolog Putative heat shock 70 kDa protein 7 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Stress-70 protein, mitochondrial mRNA export factor RAE1	A8CG34 O15504 O43301 O75190 O75694 O95429 O95757 O95816 O95817 P0DMV8 P0DMV9 P11021 P11142 P12270 P15927 P17066 P25685 P27361 P27694 P28482 P34931 P34932 P35244 P35658 P37198 P38646 P48723 P48741 P49137 P49790 P49792 P49841 P50502 P54652 P55735 P57740 P62258 P78406 Q00613 Q0VDF9 Q12769 Q13315 Q13535 Q53FT3 Q5SRE5 Q7Z3B4 Q86WX3 Q8N163 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92598 Q92621 Q96EB6 Q96HA1 Q96MM6 Q99543 Q99567 Q99615 Q99933 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7 Q9UL15	AAAS AAG2 ADRACALA APG1 APG2 AROS ATM ATR BAG1 BAG2 BAG3 BAG4 BAG5 BIS C11orf73 C20orf60 C7orf14 CAIN CAN CCAR2 CG1 D3S1231E DBC1 DNAJ1 DNAJB1 DNAJB6 DNAJC2 DNAJC7 ERK1 ERK2 FAM10A1 FRP1 GRP75 GRP78 GSK3B HAP HDJ1 HIKESHI HIP HSC70 HSF1 HSJ2 HSP105 HSP110 HSP60 HSP70B HSP70B' HSP70L1 HSP72 HSP73 HSPA1 HSPA10 HSPA12A HSPA12B HSPA13 HSPA14 HSPA1A HSPA1B HSPA1L HSPA2 HSPA4 HSPA4L HSPA5 HSPA6 HSPA7 HSPA8 HSPA9 HSPA9B HSPF1 HSPH1 HSPH2 HSPH3 HSTF1 HSX70 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0201 KIAA0225 KIAA0417 KIAA0618 KIAA0791 KIAA0873 KIAA0906 KIAA1967 MAPK1 MAPK3 MAPKAPK2 MP44 MPHOSPH11 MPP11 MRJ MRNP41 MSJ1 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 OSP94 PCNT1 POM121 POM121A POM121C PRKM1 PRKM2 PRKM3 RAE1 RANBP2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS19BP1 SEC13 SEC13A SEC13L1 SEC13R SIR2L1 SIRT1 SNC6 SODD ST13 STCH TMEM48 TPR TPR2 TTC2 YWHAE ZRF1 mt-HSP70	Homo sapiens (human)
Regulation of HMOX1 expression and activity	Heme oxygenase 1 Minor histocompatibility antigen H13 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK Transcription regulator protein BACH1	O14867 O60675 P09601 Q16236 Q8TCT9	BACH1 H13 HM13 HMOX1 HO HO1 IMP1 MAFK NFE2L2 NRF2 PSL3 SPP	Homo sapiens (human)
Regulation of Glucokinase by Glucokinase Regulatory Protein	Aladin E3 SUMO-protein ligase RanBP2 Glucokinase regulatory protein Hexokinase-4 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35557 P35658 P37198 P49790 P49792 P55735 P57740 P78406 Q12769 Q14397 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E GCK GCKR KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)	G58161NS
Regulation of FZD by ubiquitination	E3 ubiquitin-protein ligase RNF43 E3 ubiquitin-protein ligase ZNRF3 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Leucine-rich repeat-containing G-protein coupled receptor 4 Leucine-rich repeat-containing G-protein coupled receptor 5 Leucine-rich repeat-containing G-protein coupled receptor 6 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Polyubiquitin-B Polyubiquitin-C Protein Wnt-3a R-spondin-1 R-spondin-2 R-spondin-3 R-spondin-4 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60353 O75197 O75473 O75581 P0CG47 P0CG48 P40818 P56704 P62979 P62987 Q13467 Q2I0M5 Q2MKA7 Q68DV7 Q6UXX9 Q9BXB1 Q9BXY4 Q9H461 Q9HBX8 Q9ULT6 Q9ULV1	C20orf182 C2orf31 FZD4 FZD5 FZD6 FZD8 GPR48 GPR49 GPR67 KIAA0055 KIAA1133 LGR4 LGR5 LGR6 LR3 LRP5 LRP6 LRP7 PWTSR RNF203 RNF43 RPS27A RSPO1 RSPO2 RSPO3 RSPO4 THSD2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8 WNT3A ZNRF3	Homo sapiens (human)
Regulation of FOXO transcriptional activity by acetylation	CREB-binding protein Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Histone acetyltransferase KAT2B Histone acetyltransferase p300 NAD-dependent protein deacetylase sirtuin-1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Thioredoxin-interacting protein Thioredoxin	O43524 P10599 P98177 Q09472 Q12778 Q92793 Q92831 Q96EB6 Q9H3M7 Q9NTG7	AFX AFX1 CBP CREBBP EP300 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 KAT2B MLLT7 P300 PCAF SIR2L1 SIR2L3 SIRT1 SIRT3 TRDX TRX TRX1 TXN TXNIP VDUP1	Homo sapiens (human)
Regulation of Complement cascade	B-lymphocyte antigen CD19 C3a anaphylatoxin chemotactic receptor C4b-binding protein alpha chain C4b-binding protein beta chain C5a anaphylatoxin chemotactic receptor 1 C5a anaphylatoxin chemotactic receptor 2 CD59 glycoprotein CD81 antigen Carboxypeptidase B2 Carboxypeptidase N catalytic chain Carboxypeptidase N subunit 2 Clusterin Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1q subcomponent subunit C Complement C1r subcomponent Complement C1s subcomponent Complement C2 Complement C3 Complement C4-A Complement C4-B Complement C5 Complement component C6 Complement component C7 Complement component C8 alpha chain Complement component C8 beta chain Complement component C8 gamma chain Complement component C9 Complement decay-accelerating factor Complement factor B Complement factor H-related protein 1 Complement factor H-related protein 2 Complement factor H-related protein 3 Complement factor H-related protein 4 Complement factor H-related protein 5 Complement factor H Complement factor I Complement receptor type 1 Complement receptor type 2 IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Membrane cofactor protein Neutrophil elastase Plasma protease C1 inhibitor Prothrombin UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) Vitamin K-dependent protein S Vitronectin	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 P00734 P00736 P00751 P01024 P01031 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P02745 P02746 P02747 P02748 P04003 P04004 P04211 P04430 P04432 P04433 P05155 P05156 P06310 P06312 P06315 P06331 P06681 P07225 P07357 P07358 P07360 P08174 P08246 P08603 P09871 P0C0L4 P0C0L5 P0CF74 P0CG04 P0DOY2 P0DOY3 P10643 P10909 P13671 P13987 P15169 P15391 P15529 P17927 P20023 P20851 P21730 P22792 P23083 P36980 P60033 P80748 Q02985 Q03591 Q16581 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q92496 Q96IY4 Q9BXR6 Q9P296	ACBP APOJ AZ3B BF BFD C1IN C1NH C1QA C1QB C1QC C1QG C1R C1S C2 C3 C3AR1 C3BR C3DR C3R1 C4A C4B C4BP C4BPA C4BPB C4B_2 C5 C5AR C5AR1 C5AR2 C5L2 C5R1 C6 C7 C8A C8B C8G C9 CD19 CD46 CD55 CD59 CD81 CFB CFH CFHL CFHL1 CFHL1P CFHL2 CFHL3 CFHL4 CFHL5 CFHR1 CFHR1P CFHR2 CFHR3 CFHR4 CFHR5 CFI CLI CLU CO4 CPAMD1 CPAMD2 CPAMD3 CPAMD4 CPB2 CPN1 CPN2 CR CR1 CR2 DAF ELA2 ELANE F2 FHR1 FHR2 FHR3 FHR4 FHR5 GPR77 HF HF1 HF2 HFL1 HFL2 HFL3 HNFAG09 IF IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 KUB1 MCP MIC10 MIC11 MIN1 MIN2 MIN3 MSK21 PROS PROS1 SERPING1 TAPA1 TSPAN28 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VTN	Homo sapiens (human)
Regulation of CDH19 Expression and Function	Cadherin-19 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Endoribonuclease ZC3H12A Junction plakoglobin Transcription factor SOX-10	O60716 P14923 P35221 P35222 P56693 Q5D1E8 Q9H159	CDH19 CDH7L2 CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 JUP KIAA0384 MCPIP MCPIP1 SOX10 ZC3H12A	Homo sapiens (human)
Regulation of CDH11 mRNA translation by microRNAs	Cadherin-11 Helicase MOV-10 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	P55287 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 CAGH26 CDH11 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 TNRC6 TNRC6A TNRC6B TNRC6C	Homo sapiens (human)
Regulation of CDH11 gene transcription	Class E basic helix-loop-helix protein 22 Forkhead box protein F1 Hairy/enhancer-of-split related with YRPW motif-like protein Homeobox protein Hox-C8 Interleukin enhancer-binding factor 3 PR domain zinc finger protein 8 Transcription factor Sp1 Zinc finger E-box-binding homeobox 2 Zinc finger protein SNAI1	O60315 O95863 P08047 P31273 Q12906 Q12946 Q8NFJ8 Q9NQ87 Q9NQV8	BHLHB33 BHLHB5 BHLHE22 DRBF FKHL5 FOXF1 FREAC1 HEYL HOX3A HOXC8 HRT3 ILF3 KIAA0569 MPHOSPH4 NF90 PFM5 PRDM8 SIP1 SNAH SNAI1 SP1 TNRC20 TSFP1 ZEB2 ZFHX1B ZFX1B	Homo sapiens (human)
Regulation of CDH11 function	Angiopoietin-related protein 4 Cadherin-11 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Disintegrin and metalloproteinase domain-containing protein 19 Disintegrin and metalloproteinase domain-containing protein 33 Junction plakoglobin	O60716 P14923 P35221 P35222 P55287 Q9BY76 Q9BZ11 Q9H013	ADAM19 ADAM33 ANGPTL4 ARP4 C20orf153 CDH11 CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 HFARP JUP KIAA0384 MLTNB PGAR	Homo sapiens (human)
Regulation of BACH1 activity	Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 17 Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Transcription factor MafK Transcription regulator protein BACH1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14867 O60675 P0CG47 P0CG48 P62877 P62979 P62987 P63208 Q13309 Q13616 Q9UF56	BACH1 CUL1 EMC19 FBL17 FBX13 FBXL1 FBXL17 FBXO13 MAFK OCP2 RBX1 RNF75 ROC1 RPS27A SKP1 SKP1A SKP2 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Regulation of Apoptosis	Dynamin-like GTPase OPA1, mitochondrial Metalloendopeptidase OMA1, mitochondrial	O60313 Q96E52	KIAA0567 MPRP1 OMA1 OPA1	Homo sapiens (human)
Regulation of APC/C activators between G1/S and early anaphase	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 F-box only protein 5 Fizzy-related protein homolog G2/mitotic-specific cyclin-B1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06493 P14635 P20248 P24941 P30260 P51668 P51965 P60006 P78396 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UKT4 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCN1 CCNA CCNA1 CCNA2 CCNB CCNB1 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDH1 CDK1 CDK2 CDKN1 CDKN2 CENP-27 D0S1430E D17S978E E2EPF EMI1 FBX5 FBXO5 FYR FZR FZR1 KIAA1242 KIAA1406 P34CDC2 SFT TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Regulation by c-FLIP	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9	Homo sapiens (human)
Regulated proteolysis of p75NTR	Disintegrin and metalloproteinase domain-containing protein 17 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Nicastrin Nuclear factor NF-kappa-B p105 subunit Presenilin-1 Presenilin-2 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16	P08138 P19838 P49768 P49810 P78536 Q04206 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 ADAM17 APH1A APH1B CSVP KIAA0253 NCSTN NFKB1 NFKB3 NGFR PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RELA RNF85 STM2 TACE TNFRSF16 TRAF6	Homo sapiens (human)
Regorafenib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)
Regorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Reelin signalling pathway	Disabled homolog 1 Reelin SH3 domain-containing kinase-binding protein 1 Tyrosine-protein kinase Fyn Very low-density lipoprotein receptor	O75553 P06241 P78509 P98155 Q96B97	CIN85 DAB1 FYN RELN SH3KBP1 VLDLR	Homo sapiens (human)
Reduction of cytosolic Ca++ levels	Calmodulin-1 Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 2 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sorcin	O14983 P0DP23 P16615 P20020 P23634 P30626 P32418 P57103 Q01814 Q16720 Q93084 Q9UPR5	ATP2A1 ATP2A2 ATP2A3 ATP2B ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM CALM1 CAM CAM1 CNC KIAA1087 MXRA1 NCX1 NCX2 NCX3 PMCA1 PMCA2 SLC8A1 SLC8A2 SLC8A3 SRI	Homo sapiens (human)
Recycling pathway of L1	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Clathrin heavy chain 1 Clathrin light chain A Dihydropyrimidinase-related protein 2 Dynamin-1 Dynamin-2 Dynamin-3 Endophilin-A1 Ezrin Mitogen-activated protein kinase 1 Moesin Neural cell adhesion molecule L1 Protein numb homolog Radixin Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-4 Ribosomal protein S6 kinase alpha-5 Ribosomal protein S6 kinase alpha-6 Shootin-1	A0MZ66 O75582 O75676 O94973 O95239 O95782 P09496 P15311 P26038 P28482 P32004 P35241 P49757 P50570 P51812 P53680 P63010 Q00610 Q05193 Q15349 Q15418 Q16555 Q2VIQ3 Q96CW1 Q99962 Q9UK32 Q9UQ16	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 C14orf41 CAML1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CNSA2 CRMP2 DNM DNM1 DNM2 DNM3 DPYSL2 DYN2 ERK2 EZR HIP9 HYPJ ISPK1 KIAA0034 KIAA0109 KIAA0820 KIAA0899 KIAA1598 KIF4 KIF4A KIF4B L1CAM MAPK1 MAPKAPK1A MAPKAPK1B MAPKAPK1C MIC5 MSK1 MSK2 MSN NUMB PRKM1 PRKM2 RDX RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RSK1 RSK2 RSK3 RSK4 SH3D2A SH3GL2 SHTN1 ULIP2 VIL2	Homo sapiens (human)
Recycling of eIF2:GDP	Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Translation initiation factor eIF2B subunit alpha Translation initiation factor eIF2B subunit beta Translation initiation factor eIF2B subunit delta Translation initiation factor eIF2B subunit epsilon Translation initiation factor eIF2B subunit gamma	P05198 P20042 P41091 P49770 Q13144 Q14232 Q9NR50 Q9UI10	EIF2A EIF2B EIF2B1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 EIF2BA EIF2BB EIF2BD EIF2BE EIF2G EIF2S1 EIF2S2 EIF2S3	Homo sapiens (human)
Recycling of bile acids and salts	ATP-binding cassette sub-family C member 3 Albumin Bile acid receptor Bile acid-CoA Bile salt export pump Gastrotropin Hepatic sodium/bile acid cotransporter Ileal sodium/bile acid cotransporter Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Organic solute transporter subunit alpha Organic solute transporter subunit beta Retinoic acid receptor RXR-alpha Solute carrier organic anion transporter family member 1A2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 StAR-related lipid transfer protein 5	O15438 O95342 P02768 P19793 P46721 P51161 Q12908 Q14032 Q14973 Q15596 Q15788 Q86UW1 Q86UW2 Q96RI1 Q9NPD5 Q9NSY2 Q9Y2P5 Q9Y6L6	ABCB11 ABCC3 ACSB ACSVL6 ALB ASBT BAAT BAR BHLHE74 BHLHE75 BSEP CMOAT2 FABP6 FACVL3 FATP5 FXR HRR1 ILBP ILLBP ISBT LST1 LST2 MLP2 MRP3 NCOA1 NCOA2 NR1H4 NR2B1 NTCP NTCP2 OATP OATP1 OATP1A2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC OSTA OSTB RIP14 RXRA SLC10A1 SLC10A2 SLC21A3 SLC21A6 SLC21A8 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B1 SLCO1B3 SRC1 SRC2 STARD5 TIF2	Homo sapiens (human)
Recruitment of mitotic centrosome proteins and complexes	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchor protein 9 Alpha-centractin CDK5 regulatory subunit-associated protein 2 CLIP-associating protein 1 Casein kinase I isoform delta Casein kinase I isoform epsilon Centrin-2 Centriolar coiled-coil protein of 110 kDa Centriole and centriolar satellite protein OFD1 Centriolin Centromere protein J Centrosomal protein 43 Centrosomal protein of 131 kDa Centrosomal protein of 135 kDa Centrosomal protein of 152 kDa Centrosomal protein of 164 kDa Centrosomal protein of 192 kDa Centrosomal protein of 290 kDa Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 72 kDa Centrosomal protein of 76 kDa Centrosomal protein of 78 kDa Centrosome-associated protein ALMS1 Centrosome-associated protein CEP250 Cyclin-dependent kinase 11A Cyclin-dependent kinase 11B Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoskeleton-associated protein 5 Dynactin subunit 2 Dynactin subunit 3 Dynein light chain 1, cytoplasmic Gamma-tubulin complex component 2 Gamma-tubulin complex component 3 Gamma-tubulin complex component 4 Gamma-tubulin complex component 5 Gamma-tubulin complex component 6 HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 2 HAUS augmin-like complex subunit 3 HAUS augmin-like complex subunit 4 HAUS augmin-like complex subunit 5 HAUS augmin-like complex subunit 6 HAUS augmin-like complex subunit 7 HAUS augmin-like complex subunit 8 Heat shock protein HSP 90-alpha Microtubule nucleation factor SSNA1 Microtubule-associated protein RP/EB family member 1 Mitotic-spindle organizing protein 1 Mitotic-spindle organizing protein 2A Mitotic-spindle organizing protein 2B Ninein-like protein Nuclear distribution protein nudE homolog 1 Nucleoside diphosphate kinase homolog 7 Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 protein Platelet-activating factor acetylhydrolase IB subunit beta Protein NEDD1 Protein SFI1 homolog Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serologically defined colon cancer antigen 8 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin gamma-1 chain Tubulin gamma-2 chain cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit	A8K8P3 O00444 O15078 O43303 O43805 O75665 O75935 O94927 O94986 O95613 O95684 P04350 P06493 P07437 P07900 P17612 P21127 P23258 P30153 P31323 P41208 P43034 P48730 P49674 P51955 P53350 P61163 P61981 P62258 P63167 P68366 P68371 Q08AG7 Q13409 Q13561 Q14008 Q14204 Q15154 Q15691 Q5BJF6 Q5JTW2 Q66GS9 Q68CZ6 Q6NZ67 Q6P582 Q71U36 Q7Z460 Q7Z4H7 Q7Z7A1 Q86SQ7 Q86XR8 Q8NHQ1 Q8NHV4 Q8TAP6 Q8TCU4 Q8TEP8 Q96CS2 Q96CW5 Q96MT8 Q96RT7 Q96RT8 Q96SN8 Q99871 Q99996 Q9BSJ2 Q9BT25 Q9BV73 Q9BYV8 Q9H6D7 Q9HC77 Q9NRH3 Q9NVX0 Q9NXR1 Q9P209 Q9UGJ1 Q9UPN4 Q9UPV0 Q9UQ88 Q9Y2I6 Q9Y5B8	76P ACTR1A AKAP350 AKAP450 AKAP9 ALMS1 AZI1 BBS14 BITE C13orf37 C14orf94 C15orf25 C18orf9 C4orf15 C9orf81 CALT CCCAP CCDC5 CCP110 CDC2 CDC28A CDC2L1 CDC2L2 CDC2L3 CDK1 CDK11 CDK11A CDK11B CDK5RAP2 CDKN1 CEN2 CENPJ CEP1 CEP110 CEP131 CEP135 CEP152 CEP164 CEP192 CEP2 CEP215 CEP250 CEP27 CEP290 CEP4 CEP41 CEP43 CEP57 CEP63 CEP70 CEP72 CEP76 CEP78 CETN2 CKAP5 CLASP1 CNAP1 CNTRL CP110 CPAP CSNK1D CSNK1E CTRN1 CXorf5 DCTN2 DCTN22 DCTN3 DCTN50 DGT6 DHC1 DLC1 DNCH1 DNCI2 DNCIC2 DNCL DNCL1 DNCLC1 DNECL DYHC DYNC1H1 DYNC1I2 DYNLL1 FAM128A FAM128B FAM29A FGFR1OP FOP GCP2 GCP3 GCP4 GCP5 GCP6 HAUS1 HAUS2 HAUS3 HAUS4 HAUS5 HAUS6 HAUS7 HAUS8 HCKID HDLC1 HEIC HICE1 HSP90A HSP90AA1 HSPC1 HSPCA KIAA0092 KIAA0097 KIAA0325 KIAA0328 KIAA0373 KIAA0402 KIAA0419 KIAA0542 KIAA0622 KIAA0635 KIAA0803 KIAA0841 KIAA0912 KIAA0980 KIAA1052 KIAA1118 KIAA1519 KIAA1569 KIAA1574 KIAA1633 KIAA1669 KIAA1899 LAP LIP1 LIS1 MAPRE1 MAST1 MDCR MDS MOZART1 MOZART2A MOZART2B MZT1 MZT2A MZT2B NA14 NDE1 NEDD1 NEK2 NEK2A NINL NLK1 NLP NME7 NPHP10 NPHP15 NPHP6 NUDE ODF2 OFD1 P34CDC2 PAFAH1B1 PAFAHA PCM1 PCNT PCNT2 PITSLREA PITSLREB PK58 PKACA PLK PLK1 PLK4 PPP2R1A PRKACA PRKAR2B SAK SDCCAG8 SFI1 SSNA1 STK18 TSGA14 TSP57 TUBA1 TUBA1A TUBA3 TUBA4A TUBB TUBB2C TUBB4 TUBB4A TUBB4B TUBB5 TUBG TUBG1 TUBG2 TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP5 TUBGCP6 UCHL5IP UIP1 YWHAE YWHAG	Homo sapiens (human)

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