GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **651 - 675** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
FCGR3A-mediated phagocytosis	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Low affinity immunoglobulin gamma Fc region receptor III-A Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin-2 Myosin-9 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Proto-oncogene vav Putative GIPL galf transferase Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK Tyrosine-protein kinase Fgr Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes UGa8H (Fragment) Unconventional myosin-IXb Unconventional myosin-Ic Unconventional myosin-Va Unconventional myosin-X V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A6NGB9 O00159 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07947 P07948 P08631 P08637 P09693 P09769 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16333 P23083 P27361 P28482 P35579 P42768 P43405 P46108 P52735 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 P80748 Q05397 Q06187 Q13459 Q14185 Q4QD44 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92556 Q92558 Q92747 Q96F07 Q96JJ3 Q9HD67 Q9NYB9 Q9NZQ3 Q9UKW4 Q9UKX2 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y4I1 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CD16A CD3G CDC42 CED12A CR16 CRK CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK1 ERK2 FAK FAK1 FCG3 FCGR3 FCGR3A FGR FYN HCK HEM1 HEM2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IMD2 JTK7 JTK8 KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0799 KIAA0900 KIAA1168 KIAA1834 LPG1G LPG1G2 LYN MAPK1 MAPK3 MYH12 MYH2 MYH9 MYHSA2 MYO10 MYO1C MYO5A MYO9B MYR5 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SRC2 SSH3BP1 SYK T3G TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE YES YES1	Homo sapiens (human)
FGFR1b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 22 Fibroblast growth factor 2 Fibroblast growth factor 3 PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	O14908 O15520 P05230 P09038 P11487 Q03167 Q9HCT0	C19orf3 FGF1 FGF10 FGF2 FGF22 FGF3 FGFA FGFB GIPC GIPC1 INT2 RGS19IP1 TGFBR3	Homo sapiens (human)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23	Q9GZV9	FGF23 HYPF	Homo sapiens (human)
FGFR1c ligand binding and activation	Anosmin-1 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	O14908 P05230 P08620 P09038 P10767 P23352 P31371 Q03167 Q9GZV9 Q9NP95	ADMLX ANOS1 C19orf3 FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB GIPC GIPC1 HST HST2 HSTF1 HSTF2 HYPF KAL KAL1 KALIG1 KS3 RGS19IP1 TGFBR3	Homo sapiens (human)
FGFR2 alternative splicing	Cytotoxic granule associated RNA binding protein TIA1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Epithelial splicing regulatory protein 1 Epithelial splicing regulatory protein 2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein M Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nucleolysin TIAR Polypyrimidine tract-binding protein 1 RNA binding protein fox-1 homolog 2	O15514 O43251 P09651 P13984 P19387 P19388 P24928 P26599 P30876 P31483 P31943 P35269 P36954 P52272 P52298 P52434 P52435 P52597 P53803 P61218 P62487 P62875 Q01085 Q09161 Q6NXG1 Q9H6T0	CBP20 CBP80 ESRP1 ESRP2 FOX2 GTF2F1 GTF2F2 HNRNPA1 HNRNPF HNRNPH1 HNRNPM HNRPA1 HNRPF HNRPH HNRPH1 HNRPM HRNBP2 NAGR1 NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PTB PTBP1 RAP30 RAP74 RBFOX2 RBM35A RBM35B RBM9 RPB7 RTA TIA1 TIAL1	Homo sapiens (human)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 22 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 7 Fibroblast growth factor-binding protein 1 Fibroblast growth factor-binding protein 2 Fibroblast growth factor-binding protein 3	O15520 P05230 P09038 P11487 P21781 Q14512 Q8TAT2 Q9BYJ0 Q9HCT0	C10orf13 FGF1 FGF10 FGF2 FGF22 FGF3 FGF7 FGFA FGFB FGFBP FGFBP1 FGFBP2 FGFBP3 HBP17 INT2 KGF KSP37	Homo sapiens (human)
FGFR2c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P10767 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF KS3	Homo sapiens (human)
FGFR3b ligand binding and activation	Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 9	O76093 P05230 P31371 Q9NP95	FGF1 FGF18 FGF20 FGF9 FGFA	Homo sapiens (human)
FGFR3c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Polypeptide N-acetylgalactosaminyltransferase 3	O43320 O76093 P05230 P08620 P09038 P31371 Q14435 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB GALNT3 HST HSTF1 HYPF KS3	Homo sapiens (human)
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4	O43320 O76093 O95750 P05230 P08620 P09038 P10767 P22455 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 HST HST2 HSTF1 HSTF2 HYPF JTK2 KS3 TKF	Homo sapiens (human)
FGFR4 mutant receptor activation	Fibroblast growth factor receptor 4	P22455	FGFR4 JTK2 TKF	Homo sapiens (human)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 18 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor receptor-like 1 Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2	O15520 O76093 P08620 P09038 P11487 Q7Z698 Q7Z699 Q8N441 Q9GZV9 Q9HCT0	FGF10 FGF18 FGF2 FGF22 FGF23 FGF3 FGF4 FGFB FGFR5 FGFRL1 FHFR HST HSTF1 HYPF INT2 KS3 SPRED1 SPRED2	Homo sapiens (human)
FLT3 Signaling	Bcl-2-like protein 11 Cyclin-dependent kinase inhibitor 1B Fms-related tyrosine kinase 3 ligand Forkhead box protein O3 GRB2-associated-binding protein 2 GRB2-related adapter protein 2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor-type tyrosine-protein kinase FLT3 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43521 O43524 O75791 P01111 P01112 P27986 P31749 P31751 P36888 P42336 P46527 P49771 Q06124 Q07889 Q13322 Q9UQC2 Q9Y243	AKT1 AKT2 AKT3 BCL2L11 BIM CD135 CDKN1B FKHRL1 FLK2 FLT3 FLT3LG FOXO3 FOXO3A GAB2 GADS GRAP2 GRB1 GRB10 GRB2L GRBIR GRID HRAS HRAS1 KIAA0207 KIAA0571 KIP1 NRAS PIK3CA PIK3R1 PKB PKBG PTP2C PTPN11 RAC SHPTP2 SOS1 STK1 p27	Homo sapiens (human)
FLT3 mutants bind TKIs	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
FLT3 signaling by CBL mutants	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P22681 P36888 P49771 P62979 P62987	CBL CBL2 CD135 FLK2 FLT3 FLT3LG RNF55 RPS27A STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
FLT3 signaling through SRC family kinases	Fms-related tyrosine kinase 3 ligand Receptor-type tyrosine-protein kinase FLT3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	P06239 P06241 P08631 P36888 P43405 P49771	CD135 FLK2 FLT3 FLT3LG FYN HCK LCK STK1 SYK	Homo sapiens (human)
FOXO-mediated transcription of cell cycle genes	Caveolin-1 Cyclin-G2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Forkhead box protein G1 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Growth arrest and DNA damage-inducible protein GADD45 alpha Growth/differentiation factor 8 Krueppel-like factor 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Poly(rC)-binding protein 4 Protein BTG1 Retinoblastoma-like protein 2	O14793 O43474 O43524 P24522 P38936 P46527 P55316 P57723 P62324 P84022 P98177 Q03135 Q08999 Q12778 Q13485 Q15796 Q16589	AFX AFX1 BTG1 CAP20 CAV CAV1 CCNG2 CDKN1 CDKN1A CDKN1B CIP1 DDIT1 DPC4 EZF FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FKHR FKHRL1 FOXG1 FOXG1A FOXG1B FOXG1C FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD45 GADD45A GDF8 GKLF KIP1 KLF4 MADH2 MADH3 MADH4 MADR2 MDA6 MLLT7 MSTN PCBP4 PIC1 RB2 RBL2 SDI1 SMAD2 SMAD3 SMAD4 WAF1 p27	Homo sapiens (human)
FOXO-mediated transcription of cell death genes	B-cell lymphoma 6 protein Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 CREB-binding protein Cbp/p300-interacting transactivator 2 DNA damage-inducible transcript 3 protein Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Histone acetyltransferase p300 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Serine/threonine-protein kinase PINK1, mitochondrial Serine/threonine-protein kinase STK11 Tumor necrosis factor ligand superfamily member 6	O43521 O43524 P23511 P25208 P35638 P41182 P48023 P98177 Q09472 Q12778 Q13952 Q15831 Q92793 Q99967 Q9BXH1 Q9BXM7	AFX AFX1 APT1LG1 BBC3 BCL2L11 BCL5 BCL6 BIM CBP CD95L CHOP CHOP10 CITED2 CREBBP DDIT3 EP300 FASL FASLG FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD153 HAP3 LAZ3 LKB1 MLLT7 MRG1 NFYA NFYB NFYC P300 PINK1 PJS PUMA STK11 TNFSF6 ZBTB27 ZNF51	Homo sapiens (human)
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	ATP-binding cassette sub-family A member 6 Agouti-related protein Ataxin-3 Catalase E3 ubiquitin-protein ligase TRIM63 F-box only protein 32 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glucocorticoid receptor Glucose-6-phosphatase catalytic subunit 1 Hexokinase-4 Histone deacetylase 1 Histone deacetylase 2 Insulin-like growth factor-binding protein 1 Insulin Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Plexin-A4 Pro-neuropeptide Y Pro-opiomelanocortin Resistin Sterol regulatory element-binding protein 1 Superoxide dismutase [Mn], mitochondrial	A8MYZ6 O00253 O43524 P01189 P01303 P01308 P04040 P04150 P04179 P08833 P35557 P35558 P35575 P36956 P54252 P84022 P98177 Q12778 Q13485 Q13547 Q15796 Q8N139 Q92769 Q969P5 Q969Q1 Q96ST3 Q9HCM2 Q9HD89 Q9NTG7 Q9UBK2	ABCA6 AFX AFX1 AGRP AGRT ART ATX3 ATXN3 BHLHD1 CAT DPC4 FBXO32 FIZZ3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 G6PC G6PC1 G6PT GCK GRL HDAC1 HDAC2 HXCP1 IBP1 IGFBP1 INS IRF KIAA1550 LEM6 MADH2 MADH3 MADH4 MADR2 MJD MJD1 MLLT7 MURF1 NPY NR3C1 PCK1 PEPCK1 PGC1 PGC1A PLXNA4 PLXNA4A PLXNA4B POMC PPARGC1 PPARGC1A RETN RNF28 RPD3L1 RSTN SCA3 SIN3A SIR2L3 SIRT3 SMAD2 SMAD3 SMAD4 SMRZ SOD2 SREBF1 SREBP1 TRIM63	Homo sapiens (human)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43559 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
FRS-mediated FGFR3 signaling	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HSTF1 HYPF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
FRS-mediated FGFR4 signaling	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q06124 Q07889 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1 TKF	Homo sapiens (human)
Factors involved in megakaryocyte development and platelet production	A-kinase anchor protein 1, mitochondrial A-kinase anchor protein 10, mitochondrial CDK5 and ABL1 enzyme substrate 1 CDK5 and ABL1 enzyme substrate 2 Cell division control protein 42 homolog Cellular tumor antigen p53 Chromobox protein homolog 5 Cyclin-dependent kinase 2 Cyclin-dependent kinase 5 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 EH domain-containing protein 1 EH domain-containing protein 2 EH domain-containing protein 3 Endothelial transcription factor GATA-2 Erythroid transcription factor F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta F-actin-uncapping protein LRRC16A GTP Hemoglobin subunit beta Hemoglobin subunit delta Hemoglobin subunit epsilon Hemoglobin subunit gamma-1 Hemoglobin subunit gamma-2 Histone H3.1 Histone H3.2 Histone H3.3 Histone deacetylase 1 Histone deacetylase 2 Inositol-tetrakisphosphate 1-kinase Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 1 Interferon regulatory factor 2 Lysine-specific histone demethylase 1A Mitofusin-1 Mitofusin-2 PHD finger protein 21A Paired amphipathic helix protein Sin3a Probable JmjC domain-containing histone demethylation protein 2C REST corepressor 1 Rabenosyn-5 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-5A SH2B adapter protein 1 SH2B adapter protein 2 SH2B adapter protein 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor GATA-4 Transcription factor GATA-5 Transcription factor GATA-6 Transcription factor MafF Transcription factor MafG Transcription factor MafK Transcription factor NF-E2 45 kDa subunit Transcriptional activator Myb Tyrosine-protein kinase ABL1 Tyrosine-protein kinase JAK2 Vacuolar protein sorting-associated protein 45 Wee1-like protein kinase Zinc finger protein ZFPM1 Zinc finger protein ZFPM2 [F-actin]-monooxygenase MICAL1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14492 O15315 O15525 O43502 O43572 O60341 O60674 O60675 O95140 P00519 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P02042 P02100 P04637 P05013 P05014 P05015 P10242 P10644 P10914 P13861 P14316 P15976 P17612 P20339 P22612 P22694 P23769 P23771 P24941 P30291 P31321 P31323 P32881 P43694 P45973 P47755 P47756 P52907 P60953 P63000 P68431 P68871 P69891 P69892 P84243 Q00535 Q13547 Q13572 Q14185 Q15652 Q16621 Q5JSL3 Q5VZK9 Q71DI3 Q8IWA4 Q8IX07 Q8IZD9 Q8N1I0 Q8NF50 Q8TDN4 Q8TDZ2 Q8WW38 Q92608 Q92667 Q92769 Q92908 Q96BD5 Q96BY6 Q96HP0 Q96N67 Q96ST3 Q9BTV7 Q9BWX5 Q9BZ29 Q9H1K0 Q9H4M9 Q9H7D0 Q9NRF2 Q9NRW7 Q9NZN3 Q9NZN4 Q9P0W2 Q9UIJ7 Q9UKL0 Q9ULX9 Q9UQQ2	ABL ABL1 AK3 AK3L1 AK6 AKAP1 AKAP10 AKAP149 AKL3L AOF2 APS BHC80 BRAF35 C20orf150 CABLES CABLES1 CABLES2 CAPZA1 CAPZA2 CAPZB CARMIL CARMIL1 CBX5 CDC42 CDK2 CDK5 CDKN2 CDKN5 CPRP1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 EHD1 EHD2 EHD3 ERYF1 FOG1 FOG2 GATA1 GATA2 GATA3 GATA4 GATA5 GATA6 GF1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HBB HBD HBE HBE1 HBG1 HBG2 HDAC1 HDAC2 HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D HMG20B HMGX2 HMGXB2 HP1A IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IRF1 IRF2 ITPK1 JAK2 JHDM2C JMJD1C JTK7 KDM1 KDM1A KIAA0071 KIAA0209 KIAA0214 KIAA0299 KIAA0601 KIAA0694 KIAA0716 KIAA1058 KIAA1299 KIAA1380 KIAA1395 KIAA1696 KIAA1771 LNK LRRC16 LRRC16A LSD1 MAFF MAFG MAFK MFN1 MFN2 MICAL MICAL1 MOCA MYB NFE2 NICAL P53 PAST PAST1 PAST2 PAST3 PHF21A PKACA PKR1 PKR2 PRKA1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PSSALRE RAB5 RAB5A RAC1 RAD51B RAD51C RAD51L1 RAD51L2 RBSN RCOR RCOR1 REC2 RPD3L1 SH2B SH2B1 SH2B2 SH2B3 SIN3A SMARCE1R TC25 TP53 TRIP8 TSE1 VPS45 VPS45A VPS45B WEE1 ZFN89A ZFPM1 ZFPM2 ZFYVE20 ZIZ1 ZIZ2 ZIZ3 ZNF89B	Homo sapiens (human)
Fanconi Anemia Pathway	5' exonuclease Apollo ATR-interacting protein Centromere protein S Centromere protein X Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA cross-link repair 1A protein DNA excision repair protein ERCC-1 DNA polymerase nu DNA repair endonuclease XPF E3 ubiquitin-protein ligase FANCL Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group I protein Fanconi anemia group M protein Fanconi-associated nuclease 1 Polyubiquitin-B Polyubiquitin-C Probable crossover junction endonuclease EME2 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine/threonine-protein kinase ATR Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4 Ubiquitin carboxyl-terminal hydrolase 1 Ubiquitin-conjugating enzyme E2 T Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 48	A4GXA9 A8MT69 O15287 O15360 O94782 P07992 P0CG47 P0CG48 P15927 P27694 P35244 P62979 P62987 Q00597 Q0VG06 Q13535 Q6NZ36 Q6PJP8 Q7Z5Q5 Q8IY92 Q8IYD8 Q8N2Z9 Q8NB91 Q8TAF3 Q8WXE1 Q92889 Q96AY2 Q96NY9 Q9BQ83 Q9BTP7 Q9BXW9 Q9H816 Q9HB96 Q9NPD8 Q9NPI8 Q9NVI1 Q9NW38 Q9Y2M0	AGS1 APITD1 ATR ATRIP BTBD12 C17orf70 C19orf40 C1orf86 CENPS CENPX DCLRE1A DCLRE1B EME1 EME2 ERCC1 ERCC11 ERCC4 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACD FACE FAN1 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCH FANCI FANCL FANCM FRP1 GIYD1 GIYD2 KIAA0086 KIAA1018 KIAA1449 KIAA1596 KIAA1784 KIAA1794 KIAA1987 MHF1 MHF2 MMS4 MTMR15 MUS81 PHF9 POLN REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SLX1 SLX1A SLX1B SLX4 SNM1 SNM1A SNM1B STRA13 UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2T USP1 WDR48 XPF XRCC9	Homo sapiens (human)

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