GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **701 - 725** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
Translation of Structural Proteins	Envelope small membrane protein Membrane protein Nucleoprotein ORF3a protein Spike glycoprotein	P59594 P59595 P59596 P59632 P59637	3a E M N S sM	Homo sapiens (human)
Biosynthesis of maresins	Bifunctional epoxide hydrolase 2 Polyunsaturated fatty acid 5-lipoxygenase	P09917 P34913	ALOX5 EPHX2 LOG5	Homo sapiens (human)
Defective F8 cleavage by thrombin	Coagulation factor VIII Prothrombin von Willebrand factor	P00451 P00734 P04275	F2 F8 F8C F8VWF VWF	Homo sapiens (human)
Voltage gated Potassium channels	Potassium voltage-gated channel subfamily A member 10 Potassium voltage-gated channel subfamily A member 1 Potassium voltage-gated channel subfamily A member 2 Potassium voltage-gated channel subfamily A member 3 Potassium voltage-gated channel subfamily A member 4 Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily A member 6 Potassium voltage-gated channel subfamily A member 7 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily B member 2 Potassium voltage-gated channel subfamily C member 1 Potassium voltage-gated channel subfamily C member 2 Potassium voltage-gated channel subfamily C member 3 Potassium voltage-gated channel subfamily C member 4 Potassium voltage-gated channel subfamily D member 1 Potassium voltage-gated channel subfamily D member 2 Potassium voltage-gated channel subfamily D member 3 Potassium voltage-gated channel subfamily F member 1 Potassium voltage-gated channel subfamily G member 1 Potassium voltage-gated channel subfamily G member 2 Potassium voltage-gated channel subfamily G member 3 Potassium voltage-gated channel subfamily G member 4 Potassium voltage-gated channel subfamily H member 1 Potassium voltage-gated channel subfamily H member 2 Potassium voltage-gated channel subfamily H member 3 Potassium voltage-gated channel subfamily H member 4 Potassium voltage-gated channel subfamily H member 5 Potassium voltage-gated channel subfamily H member 6 Potassium voltage-gated channel subfamily H member 7 Potassium voltage-gated channel subfamily H member 8 Potassium voltage-gated channel subfamily KQT member 1 Potassium voltage-gated channel subfamily KQT member 2 Potassium voltage-gated channel subfamily KQT member 3 Potassium voltage-gated channel subfamily KQT member 4 Potassium voltage-gated channel subfamily KQT member 5 Potassium voltage-gated channel subfamily S member 1 Potassium voltage-gated channel subfamily S member 2 Potassium voltage-gated channel subfamily S member 3 Potassium voltage-gated channel subfamily V member 1 Potassium voltage-gated channel subfamily V member 2 Voltage-gated potassium channel subunit beta-1 Voltage-gated potassium channel subunit beta-2 Voltage-gated potassium channel subunit beta-3	O43448 O43525 O43526 O95259 P16389 P17658 P22001 P22459 P22460 P48547 P51787 P56696 Q03721 Q09470 Q12809 Q13303 Q14003 Q14721 Q14722 Q16322 Q6PIU1 Q8NCM2 Q8TAE7 Q8TDN1 Q8TDN2 Q92953 Q96KK3 Q96L42 Q96PR1 Q96RP8 Q9BQ31 Q9H252 Q9H3M0 Q9NR82 Q9NS40 Q9NSA2 Q9NZV8 Q9UIX4 Q9UJ96 Q9UK17 Q9ULD8 Q9ULS6 Q9UQ05	C1orf30 EAG EAG1 EAG2 ERG ERG1 ERG2 ERG3 HERG HGK5 KCNA1 KCNA10 KCNA1B KCNA2 KCNA2B KCNA3 KCNA3B KCNA4 KCNA4L KCNA5 KCNA6 KCNA7 KCNA8 KCNA9 KCNAB1 KCNAB2 KCNAB3 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNF2 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNK2 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KIAA1044 KIAA1144 KIAA1282 KVLQT1	Homo sapiens (human)
Negative regulation of MAPK pathway	14-3-3 protein beta/alpha BRCA1-associated protein Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 16 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase 2 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 5 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase 8 Dual specificity protein phosphatase 9 GTPase HRas GTPase NRas Kinase suppressor of Ras 1 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Polyubiquitin-B Polyubiquitin-C Progestin and adipoQ receptor family member 3 RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 5 Tyrosine-protein phosphatase non-receptor type 3 Tyrosine-protein phosphatase non-receptor type 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01111 P01112 P04049 P0CG47 P0CG48 P10398 P15056 P26045 P27361 P27448 P28482 P28562 P30086 P30153 P30154 P31946 P35236 P53041 P53778 P62714 P62979 P62987 P67775 Q05923 Q13115 Q13202 Q13362 Q14738 Q15172 Q15173 Q16537 Q16690 Q16828 Q16829 Q6TCH7 Q7Z569 Q8IVT5 Q99956 Q9BY84 Q9Y6W6	ARAF ARAF1 BRAF BRAF1 BRAP C11orf81 CL100 CTAK1 DUSP1 DUSP10 DUSP16 DUSP2 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 EMK2 ERK1 ERK2 ERK6 HRAS HRAS1 KIAA0044 KIAA1700 KSR KSR1 MAPK1 MAPK12 MAPK3 MARK3 MKP1 MKP2 MKP3 MKP4 MKP5 MKP7 NRAS PAC1 PAQR3 PBP PEBP PEBP1 PKS PKS2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP5 PPP5C PRKM1 PRKM2 PRKM3 PTPH1 PTPN10 PTPN3 PTPN7 PYST1 PYST2 RAF RAF1 RAFB1 RNF52 RPS27A SAPK3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VH1 VH2 VH3 VH5 YWHAB	Homo sapiens (human)
Serotonin Neurotransmitter Release Cycle	Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q05940 Q13136 Q16623 Q86UR5 Q92777	BZRAP1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VMAT2	Homo sapiens (human)
Free fatty acid receptors	12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4	O00270 O14842 O14843 O15552 Q5NUL3	FFA2 FFAR1 FFAR2 FFAR3 FFAR4 GPCR43 GPR120 GPR129 GPR31 GPR40 GPR41 GPR43 O3FAR1 PGR4	Homo sapiens (human)
Defective GFPT1 causes CMSTA1	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	Q06210	GFAT GFPT GFPT1	Homo sapiens (human)
Interleukin-17 signaling	Interleukin-17 receptor A Interleukin-17 receptor B Interleukin-17 receptor C Interleukin-17 receptor E Interleukin-17A Interleukin-17C Interleukin-17F Interleukin-25 ORF8 protein	P0DTC8 Q16552 Q8NAC3 Q8NFR9 Q96F46 Q96PD4 Q9H293 Q9NRM6 Q9P0M4	8 CRL4 CTLA8 EVI27 IL17 IL17A IL17BR IL17C IL17E IL17F IL17R IL17RA IL17RB IL17RC IL17RE IL25	Homo sapiens (human)
Defective SFTPA2 causes IPF	Pulmonary surfactant-associated protein A2	Q8IWL1	COLEC5 PSAP SFTP1 SFTPA SFTPA2 SFTPA2B	Homo sapiens (human)
The proton buffering model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5	Homo sapiens (human)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14757 O14818 O43242 O75832 O96017 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30304 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	C7orf76 CDC25A CDS1 CHEK1 CHEK2 CHK1 CHK2 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RAD53 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
TICAM1 deficiency - HSE	TIR domain-containing adapter molecule 1 Toll-like receptor 3	O15455 Q8IUC6	PRVTIRB TICAM1 TLR3 TRIF	Homo sapiens (human)
Axonal growth stimulation	Beta-nerve growth factor Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P52565 P61586	ARH12 ARHA ARHGDIA GDIA1 NGF NGFB NGFR RHO12 RHOA TNFRSF16	Homo sapiens (human)
CLEC7A (Dectin-1) induces NFAT activation	Calcineurin subunit B type 1 Calmodulin-1 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 2 Nuclear factor of activated T-cells, cytoplasmic 3 Protein phosphatase 3 catalytic subunit alpha S-adenosylhomocysteine hydrolase-like protein 1 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	O43865 O95644 P0DP23 P16298 P63098 Q08209 Q12968 Q13469 Q14571 Q14573 Q14643	AHCYL1 CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CNA CNA2 CNB DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 NFAT1 NFAT2 NFAT4 NFATC NFATC1 NFATC2 NFATC3 NFATP PPP3CA PPP3CB PPP3R1 XPVKONA	Homo sapiens (human)
Defective F8 binding to the cell membrane	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Prostacyclin signalling through prostacyclin receptor	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Prostacyclin receptor	O14610 O14775 O60262 P16520 P43119 P50150 P50151 P59768 P61952 P62873 P62879 P63092 P63211 P63215 P63218 Q5JWF2 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP PRIPR PTGIR	Homo sapiens (human)
Nuclear import of Rev protein	Aladin E3 SUMO-protein ligase RanBP2 GTP-binding nuclear protein Ran Importin subunit beta-1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleophosmin Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Regulator of chromosome condensation mRNA export factor RAE1	A8CG34 O15504 O75694 P06748 P12270 P18754 P35658 P37198 P49790 P49792 P55735 P57740 P62826 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA ARA24 C7orf14 CAIN CAN CG1 CHC1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNB1 MP44 MRNP41 NDC1 NPAP60L NPM NPM1 NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RAN RANBP2 RCC1 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
Resistance of ERBB2 KD mutants to AEE788	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
SLIT2:ROBO1 increases RHOA activity	Roundabout homolog 1 Slit homolog 2 protein Transforming protein RhoA Unconventional myosin-IXb	O94813 P61586 Q13459 Q9Y6N7	ARH12 ARHA DUTT1 MYO9B MYR5 RHO12 RHOA ROBO1 SLIL3 SLIT2	Homo sapiens (human)
Defective SLC6A5 causes hyperekplexia 3 (HKPX3)	Sodium- and chloride-dependent glycine transporter 2	Q9Y345	GLYT2 NET1 SLC6A5	Homo sapiens (human)
Protein lipoylation	Acyl carrier protein, mitochondrial Adrenodoxin, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Lipoyl amidotransferase LIPT1, mitochondrial Lipoyl synthase, mitochondrial NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Octanoyl-[acyl-carrier-protein]	A6NK58 O14561 O43766 P10109 P10515 P11182 P23434 P36957 Q9UMS0 Q9Y234	ADX BCATE2 BCKDHE2 DBT DLAT DLST DLTA DLTS FDX1 GCSH HIRIP5 LAS LIAS LIPT1 LIPT2 NDUFAB1 NFU1	Homo sapiens (human)
NRIF signals cell death from the nucleus	Beta-nerve growth factor Centromere protein R Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Mitogen-activated protein kinase 8 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01138 P08138 P0CG47 P0CG48 P45983 P49768 P49810 P62979 P62987 Q13352 Q13501 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 APH1A APH1B CENPR ITGB3BP JNK1 KIAA0253 MAPK8 NCSTN NGF NGFB NGFR NRIF3 ORCA OSIL PEN2 PRKM8 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF85 RPS27A SAPK1 SAPK1C SQSTM1 STM2 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Keratan sulfate biosynthesis	Aggrecan core protein Beta-1,4-galactosyltransferase 1 Beta-1,4-galactosyltransferase 2 Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase 6 Beta-1,4-glucuronyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Carbohydrate sulfotransferase 1 Carbohydrate sulfotransferase 2 Carbohydrate sulfotransferase 5 Carbohydrate sulfotransferase 6 Fibromodulin Keratocan Lumican Mimecan N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 Nucleotide sugar transporter SLC35D2 Osteomodulin Prolargin Type 2 lactosamine alpha-2,3-sialyltransferase UDP-GlcNAc	O43286 O43505 O43916 O60512 O60513 O60909 O60938 P15291 P16112 P20774 P51884 P51888 Q06828 Q11201 Q11203 Q11206 Q16842 Q76EJ3 Q8NFL0 Q99983 Q9C0J1 Q9GZS9 Q9GZX3 Q9NY97 Q9UBX8 Q9Y274 Q9Y2A9 Q9Y4C5	ACAN AGC1 B3GALT7 B3GALT8 B3GNT1 B3GNT2 B3GNT3 B3GNT4 B3GNT6 B3GNT7 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 B4GAT1 CGS23 CHST1 CHST2 CHST5 CHST6 CSPG1 FM FMOD GGTB2 GN6ST HFRC KERA LDC LUM MSK16 NANTA3 OGN OIF OMD PRELP SIAT10 SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SLC35D2 SLRR2A SLRR2B SLRR2C SLRR2D SLRR2E SLRR3A ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL6 STZ TMEM3 UGTREL8	Homo sapiens (human)
Synthesis of very long-chain fatty acyl-CoAs	17-beta-hydroxysteroid dehydrogenase type 3 Fatty acid CoA ligase Acsl3 Long-chain fatty acid transport protein 3 Long-chain-fatty-acid--CoA ligase 1 Long-chain-fatty-acid--CoA ligase 4 Long-chain-fatty-acid--CoA ligase 5 Long-chain-fatty-acid--CoA ligase 6 Long-chain-fatty-acid--CoA ligase ACSBG1 Long-chain-fatty-acid--CoA ligase ACSBG2 Malonate--CoA ligase ACSF3, mitochondrial Trans-2,3-enoyl-CoA reductase-like Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 4 Very long chain fatty acid elongase 5 Very long chain fatty acid elongase 6 Very long chain fatty acid elongase 7 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 Very-long-chain 3-oxoacyl-CoA reductase Very-long-chain enoyl-CoA reductase	A1L3X0 B0YJ81 O60488 O95573 P33121 P37058 Q4G176 Q53GQ0 Q5FVE4 Q5HYJ1 Q5K4L6 Q5VWC8 Q6Y1H2 Q96GR2 Q9BW60 Q9GZR5 Q9H5J4 Q9HB03 Q9NXB9 Q9NYP7 Q9NZ01 Q9P035 Q9UKU0 Q9ULC5	ACS2 ACS3 ACS4 ACS5 ACSBG1 ACSBG2 ACSF3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ACSVL3 BGM BGR BIND1 CIG30 EDH17B3 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL4 ELOVL5 ELOVL6 ELOVL7 FACE FACL1 FACL2 FACL3 FACL4 FACL5 FACL6 FATP3 GPSN2 HACD1 HACD2 HACD3 HACD4 HSD17B12 HSD17B3 KIAA0631 KIAA0837 LACS LACS1 LACS2 LACS3 LACS4 LACS5 LCE LPD PTPLA PTPLAD1 PTPLAD2 PTPLB SC2 SDR12C1 SDR12C2 SLC27A3 SRD5A2L2 SSC1 SSC2 TECR TECRL	Homo sapiens (human)

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