GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **801 - 825** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Regulation of RUNX1 Expression and Activity	Core-binding factor subunit beta Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 Helicase MOV-10 Protein PML Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tyrosine-protein phosphatase non-receptor type 11	P12931 P24385 P29590 P30279 P30281 Q00534 Q01196 Q06124 Q13951 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 AML1 BCL1 CAGH26 CBFA2 CBFB CCND1 CCND2 CCND3 CDK6 CDKN6 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 MYL PML PP8675 PRAD1 PTP2C PTPN11 RNF71 RUNX1 SHPTP2 SRC SRC1 TNRC6 TNRC6A TNRC6B TNRC6C TRIM19	Homo sapiens (human)
Ion influx/efflux at host-pathogen interface	Copper transport protein ATOX1 Copper-transporting ATPase 1 Natural resistance-associated macrophage protein 1 PDZ domain-containing protein 11	O00244 P49279 Q04656 Q5EBL8	AIPP1 ATOX1 ATP7A HAH1 LSH MC1 MNK NRAMP NRAMP1 PDZD11 PDZK11 PISP SLC11A1	Homo sapiens (human)
NOTCH2 Activation and Transmission of Signal to the Nucleus	Contactin-1 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Midkine Neurogenic locus notch homolog protein 2 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P21741 P49768 P49810 P62979 P62987 P78504 Q04721 Q12860 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9Y219	AD3 AD4 ADAM10 APH1A APH1B CNTN1 DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MDK MIB1 MIB2 MK1 NCSTN NEGF2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH2 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Condensation of Prophase Chromosomes	Condensin-2 complex subunit D3 Condensin-2 complex subunit G2 Condensin-2 complex subunit H2 Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.1t Histone H3.2 Histone H3.3 Histone H4 Microcephalin N-lysine methyltransferase KMT5A Protein SET Retinoblastoma-associated protein Serine/threonine-protein kinase PLK1 Structural maintenance of chromosomes protein 2 Structural maintenance of chromosomes protein 4	O60814 O95347 P04908 P06400 P06493 P06899 P0C5Y9 P14635 P16104 P20671 P23527 P33778 P42695 P53350 P57053 P58876 P62805 P62807 P68431 P84243 Q01105 Q16695 Q16777 Q16778 Q6FI13 Q6IBW4 Q71DI3 Q71UI9 Q86XI2 Q8N257 Q8NEM0 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9NQR1 Q9NTJ3	CAPC CAPD3 CAPE CAPH2 CCNB CCNB1 CDC2 CDC28A CDK1 CDKN1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3-4 H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 KIAA0056 KMT5A LUZP5 MCPH1 NCAPD3 NCAPG2 NCAPH2 P34CDC2 PLK PLK1 PRSET7 RB1 SET SET07 SET8 SETD8 SMC2 SMC2L1 SMC4 SMC4L1 TSH2B	Homo sapiens (human)
Serotonin Neurotransmitter Release Cycle	Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q05940 Q13136 Q16623 Q86UR5 Q92777	BZRAP1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VMAT2	Homo sapiens (human)
Glutamate Neurotransmitter Release Cycle	Complexin-1 Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Excitatory amino acid transporter 5 Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 PRA1 family protein 3 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Sodium-coupled neutral amino acid symporter 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular glutamate transporter 1	O00341 O14795 O14810 O75145 O75334 O75335 O75915 O94925 O95153 P20336 P21579 P43003 P43004 P43005 P48664 P60880 P63027 Q13136 Q16623 Q86UR5 Q96QD8 Q9P2U7 Q9UI32	ARL6IP5 ATA2 BNPI BZRAP1 CPLX1 DERP11 EAAC1 EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 GA GLAST GLAST1 GLS GLS1 GLS2 GLT1 HEAAC1 JWA KIAA0340 KIAA0612 KIAA0654 KIAA0838 KIAA0897 KIAA1382 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PRA2 PRAF3 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SAT2 SLC17A7 SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC38A2 SNAP SNAP25 SNAT2 STX1 STX1A SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VGLUT1	Homo sapiens (human)
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	O14810 P11142 P20336 P21579 P60880 P63027 Q05329 Q16623 Q86UR5 Q99259 Q9H3Z4 Q9H598	CLN4 CPLX1 DNAJC5 GAD GAD1 GAD2 GAD65 GAD67 HSC70 HSP73 HSPA10 HSPA8 KIAA0340 RAB3A RAB3IP2 RIM1 RIMS1 SLC32A1 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 VAMP2 VGAT VIAAT	Homo sapiens (human)
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Complement receptor type 1 Core-binding factor subunit beta Cytotoxic T-lymphocyte protein 4 Forkhead box protein P3 Interferon gamma Interleukin-2 receptor subunit alpha Interleukin-2 Nuclear factor of activated T-cells, cytoplasmic 2 Runt-related transcription factor 1 Tumor necrosis factor receptor superfamily member 18	P01579 P01589 P16410 P17927 P60568 Q01196 Q13469 Q13951 Q9BZS1 Q9Y5U5	AITR AML1 C3BR CBFA2 CBFB CD152 CR1 CTLA4 FOXP3 GITR IFNG IL2 IL2RA IPEX NFAT1 NFATC2 NFATP RUNX1 TNFRSF18	Homo sapiens (human)
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function	Complement component 1 Q subcomponent-binding protein, mitochondrial Tumor suppressor ARF	Q07021 Q8N726	C1QBP CDKN2 CDKN2A GC1QBP HABP1 MLM SF2P32	Homo sapiens (human)
Apoptotic factor-mediated response	Complement component 1 Q subcomponent-binding protein, mitochondrial Tumor suppressor ARF	Q07021 Q8N726	C1QBP CDKN2 CDKN2A GC1QBP HABP1 MLM SF2P32	Homo sapiens (human)
Alternative complement activation	Complement C3 Complement factor B Complement factor D Granzyme M	P00746 P00751 P01024 P51124	BF BFD C3 CFB CFD CPAMD1 DF GZMM MET1 PFD	Homo sapiens (human)
Activation of C3 and C5	Complement C2 Complement C3 Complement C4-A Complement C4-B Complement C5 Complement factor B	P00751 P01024 P01031 P06681 P0C0L4 P0C0L5	BF BFD C2 C3 C4A C4B C4B_2 C5 CFB CO4 CPAMD1 CPAMD2 CPAMD3 CPAMD4	Homo sapiens (human)
Lectin pathway of complement activation	Collectin-10 Collectin-11 Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1 Mannose-binding protein C	O00602 O75636 P11226 P48740 Q15485 Q9BWP8 Q9Y6Z7	CLL1 COLEC1 COLEC10 COLEC11 CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 MBL MBL2 PRSS5	Homo sapiens (human)	G49108TO G57321FI
Initial triggering of complement	Collectin-10 Collectin-11 Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1q subcomponent subunit C Complement C1r subcomponent Complement C1s subcomponent Complement C2 Complement C4-A Complement C4-B Ficolin-1 Ficolin-2 Ficolin-3 IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Mannan-binding lectin serine protease 1 Mannose-binding protein C UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00602 O75636 P00736 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P02745 P02746 P02747 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P06681 P09871 P0C0L4 P0C0L5 P0CF74 P0CG04 P0DOY2 P0DOY3 P11226 P23083 P48740 P80748 Q15485 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9BWP8 Q9Y6Z7	C1QA C1QB C1QC C1QG C1R C1S C2 C4A C4B C4B_2 CLL1 CO4 COLEC1 COLEC10 COLEC11 CPAMD2 CPAMD3 CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 MASP1 MBL MBL2 PRSS5 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6	Homo sapiens (human)	G49108TO G57321FI
RUNX2 regulates genes involved in cell migration	Collagenase 3 Core-binding factor subunit beta Integrin alpha-5 Integrin beta-like protein 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	O95965 P08648 P31749 P31751 P45452 Q13951 Q9Y243	AKT1 AKT2 AKT3 CBFB FNRA ITGA5 ITGBL1 MMP13 OSCP PKB PKBG RAC TIED	Homo sapiens (human)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Collagen alpha-2(I) chain Cyclin-C Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E3 ubiquitin-protein ligase Arkadia Furin Histone acetyltransferase p300 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein Plasminogen activator inhibitor 1 Polyubiquitin-B Polyubiquitin-C Retinoblastoma-like protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5 Transcription factor JunB Transcription factor Sp1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1 Y-box-binding protein 1	O00255 O15105 O60563 O60583 O75909 P01106 P05121 P08047 P08123 P09958 P0CG47 P0CG48 P17275 P24863 P27361 P28482 P28749 P42772 P49336 P50750 P62979 P62987 P67809 P84022 Q09472 Q13485 Q13547 Q14186 Q14188 Q15329 Q15583 Q15796 Q16254 Q6ZNA4 Q9GZN2 Q9GZV5	BHLHE39 CCNC CCNK CCNT1 CCNT2 CDC2L4 CDK8 CDK9 CDKN2B COL1A2 CPR4 DP1 DP2 DPC4 E2F4 E2F5 EP300 ERK1 ERK2 FUR FURIN HDAC1 JUNB MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 MEN1 MTS2 MYC NSEP1 P300 PACE PAI1 PCSK3 PLANH1 PRKM1 PRKM2 PRKM3 RBL1 RNF111 RPD3L1 RPS27A SCG2 SERPINE1 SMAD2 SMAD3 SMAD4 SMAD7 SP1 TAK TAZ TFDP1 TFDP2 TGIF TGIF1 TGIF2 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWTR1 YB1 YBX1	Homo sapiens (human)
Signaling by PDGF	Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(VI) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(VI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(VI) chain Furin Osteopontin Plasminogen Platelet-derived growth factor D Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Thrombospondin-1 Thrombospondin-2 Thrombospondin-3 Thrombospondin-4 Tissue-type plasminogen activator Tyrosine-protein phosphatase non-receptor type 12	A6NMZ7 A8TX70 P00747 P00750 P01127 P02462 P07996 P08572 P09619 P09958 P10451 P12109 P12110 P12111 P16234 P20849 P29400 P35442 P35443 P49746 P53420 Q01955 Q05209 Q14050 Q14055 Q9GZP0	BNSP COL29A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL9A1 COL9A2 COL9A3 FUR FURIN IEGF OPN PACE PCSK3 PDGF2 PDGFB PDGFD PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PLAT PLG PTPN12 RHEPDGFRA SCDGFB SIS SPP1 THBS1 THBS2 THBS3 THBS4 TSP TSP1 TSP2 TSP3 TSP4 VWA4	Homo sapiens (human)
Collagen chain trimerization	Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(V) chain Collagen alpha-1(VI) chain Collagen alpha-1(VII) chain Collagen alpha-1(VIII) chain Collagen alpha-1(X) chain Collagen alpha-1(XI) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XX) chain Collagen alpha-1(XXI) chain Collagen alpha-1(XXII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXIV) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-1(XXVII) chain Collagen alpha-1(XXVIII) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(V) chain Collagen alpha-2(VI) chain Collagen alpha-2(VIII) chain Collagen alpha-2(XI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(V) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(IV) chain Collagen alpha-6(VI) chain	A6NMZ7 A8TX70 P02452 P02458 P02461 P02462 P05997 P08123 P08572 P12107 P12109 P12110 P12111 P13942 P20849 P20908 P25067 P25940 P27658 P29400 P39059 P39060 P53420 Q01955 Q02388 Q03692 Q05707 Q07092 Q14031 Q14050 Q14055 Q14993 Q17RW2 Q2UY09 Q5TAT6 Q86Y22 Q8IZC6 Q8NFW1 Q96A83 Q96P44 Q99715 Q9BXS0 Q9P218 Q9UMD9	BP180 BPAG2 C3orf7 COL10A1 COL11A1 COL11A2 COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL1AL COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL26A1 COL27A1 COL28 COL28A1 COL29A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COLL6 EMID2 EMU2 KIAA1510 KIAA1870 UND VWA4	Homo sapiens (human)
Establishment of Sister Chromatid Cohesion	Cohesin subunit SA-1 Cohesin subunit SA-2 Double-strand-break repair protein rad21 homolog N-acetyltransferase ESCO1 N-acetyltransferase ESCO2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Sororin Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Wings apart-like protein homolog	O60216 Q14683 Q29RF7 Q56NI9 Q5FWF5 Q7Z5K2 Q8N3U4 Q8WVM7 Q96FF9 Q9NTI5 Q9UQE7	APRIN AS3 BAM BMH CDCA5 CSPG6 DXS423E EFO1 ESCO1 ESCO2 FOE HR21 KIAA0078 KIAA0178 KIAA0261 KIAA0648 KIAA0979 KIAA1911 NXP1 PDS5 PDS5A PDS5B RAD21 SA1 SA2 SB1.8 SCC1 SCC3 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 STAG1 STAG2 WAPAL WAPL	Homo sapiens (human)
Cohesin Loading onto Chromatin	Cohesin subunit SA-1 Cohesin subunit SA-2 Double-strand-break repair protein rad21 homolog MAU2 chromatid cohesion factor homolog Nipped-B-like protein Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Wings apart-like protein homolog	O60216 Q14683 Q29RF7 Q6KC79 Q7Z5K2 Q8N3U4 Q8WVM7 Q9NTI5 Q9UQE7 Q9Y6X3	APRIN AS3 BAM BMH CSPG6 DXS423E FOE HR21 IDN3 KIAA0078 KIAA0178 KIAA0261 KIAA0648 KIAA0892 KIAA0979 MAU2 NIPBL NXP1 PDS5 PDS5A PDS5B RAD21 SA1 SA2 SB1.8 SCC1 SCC2 SCC3 SCC4 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 STAG1 STAG2 WAPAL WAPL	Homo sapiens (human)
RHO GTPases Activate ROCKs	Cofilin-1 LIM domain kinase 1 LIM domain kinase 2 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein kinase PAK 1 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14950 O14974 O60237 O75116 P08134 P23528 P24844 P35579 P35580 P35749 P53667 P53671 P60660 P61586 P62140 P62745 Q13153 Q13464 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CFL CFL1 KIAA0619 KIAA0866 KIAA2034 LIMK LIMK1 LIMK2 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PAK1 PPP1CB PPP1R12A PPP1R12B RHO12 RHOA RHOB RHOC ROCK1 ROCK2	Homo sapiens (human)
Sema3A PAK dependent Axon repulsion	Cofilin-1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O75051 O75914 P06241 P07332 P07900 P08238 P23528 P51805 P53667 P63000 Q13153 Q13177 Q14563 Q9HCM2 Q9UIW2	CFL CFL1 FES FPS FYN HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0463 KIAA1550 LIMK LIMK1 NOV NRP NRP1 OCT OPHN3 PAK1 PAK2 PAK3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 SEMA3A SEMAD SEX TC25 VEGF165R	Homo sapiens (human)
Cobalamin (Cbl) metabolism	Cobalamin trafficking protein CblD Corrinoid adenosyltransferase MMAB Cyanocobalamin reductase / alkylcobalamin dealkylase Methionine synthase reductase Methionine synthase Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA mutase, mitochondrial	P22033 Q8IVH4 Q96EY8 Q99707 Q9H3L0 Q9UBK8 Q9Y4U1	C2orf25 CL25022 MMAA MMAB MMACHC MMADHC MMUT MTR MTRR MUT	Homo sapiens (human)
Defective CBLIF causes IFD	Cobalamin binding intrinsic factor	P27352	CBLIF GIF IFMH	Homo sapiens (human)
Defective AMN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)

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