GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **826 - 850** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
STAT6-mediated induction of chemokines	Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 6 Stimulator of interferon genes protein	P42226 Q86WV6 Q9UHD2	ERIS MITA NAK STAT6 STING STING1 TBK1 TMEM173	Homo sapiens (human)
Translesion Synthesis by POLH	DNA polymerase eta DNA-dependent metalloprotease SPRTN Nuclear protein localization protein 4 homolog Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RING finger and CHY zinc finger domain-containing protein 1 Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transitional endoplasmic reticulum ATPase Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P12004 P15927 P27694 P35244 P35249 P35250 P35251 P40937 P40938 P55072 P62979 P62987 Q8TAT6 Q92890 Q96PM5 Q9H040 Q9Y253	ARNIP C1orf124 CHIMP DVC1 HEL-220 HEL-S-70 KIAA1499 NPL4 NPLOC4 PCNA PIRH2 POLH RAD30 RAD30A RCHY1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF199 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SPRTN UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UFD1 UFD1L VCP XPV ZNF363	Homo sapiens (human)
Purine ribonucleoside monophosphate biosynthesis	Adenylosuccinate lyase Adenylosuccinate synthetase isozyme 1 Adenylosuccinate synthetase isozyme 2 Amidophosphoribosyltransferase Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Bifunctional purine biosynthesis protein ATIC GMP synthase [glutamine-hydrolyzing] Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Phosphoribosylformylglycinamidine synthase Trifunctional purine biosynthetic protein adenosine-3	O15067 P12268 P20839 P22102 P22234 P30520 P30566 P31939 P49915 Q06203 Q8N142	ADE2 ADSL ADSS ADSS1 ADSS2 ADSSL1 AIRC AMPS ATIC GART GMPS GPAT IMPD1 IMPD2 IMPDH1 IMPDH2 KIAA0361 PAICS PAIS PFAS PGFT PPAT PRGS PURH	Homo sapiens (human)
Regulation of PAK-2p34 activity by PS-GAP/RHG10	Rho GTPase-activating protein 10 Serine/threonine-protein kinase PAK 2	A1A4S6 Q13177	ARHGAP10 GRAF2 PAK2	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
Attenuation phase	CREB-binding protein DnaJ homolog subfamily B member 1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor protein 1 Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Histone acetyltransferase p300 Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3	O75506 P07900 P08238 P0DMV8 P0DMV9 P11142 P25685 P34931 P54652 Q00613 Q02790 Q09472 Q15185 Q92793	CBP CREBBP DNAJ1 DNAJB1 EP300 FKBP4 FKBP52 HDJ1 HSBP1 HSC70 HSF1 HSF1BP HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSTF1 HSX70 P23 P300 PTGES3 TEBP	Homo sapiens (human)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase delta Diacylglycerol kinase epsilon Diacylglycerol kinase eta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase kappa Diacylglycerol kinase theta Diacylglycerol kinase zeta Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O75912 O95267 P23743 P24723 P49619 P52429 P52824 Q02156 Q04759 Q05655 Q13507 Q13574 Q14571 Q14573 Q14643 Q16760 Q5KSL6 Q7LDG7 Q86XP1 Q9HCX4 Q9Y210 Q9Y6T7	CDC25L DAGK DAGK1 DAGK2 DAGK3 DAGK4 DAGK5 DAGK6 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKK DGKQ DGKZ INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0145 KIAA0718 MCG7 PKCD PKCE PKCL PRKCD PRKCE PRKCH PRKCL PRKCQ PRKCT RASGRP RASGRP1 RASGRP2 TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
Pre-NOTCH Processing in Golgi	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Beta-1,3-N-acetylglucosaminyltransferase manic fringe Beta-1,3-N-acetylglucosaminyltransferase radical fringe Beta-1,4-galactosyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Furin Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein sel-1 homolog 1 Ras-related protein Rab-6A Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Transmembrane emp24 domain-containing protein 2 Type 2 lactosamine alpha-2,3-sialyltransferase	O00587 O14983 P09958 P15291 P16615 P20340 P46531 Q04721 Q11203 Q11206 Q15363 Q8NES3 Q93084 Q99466 Q9UBV2 Q9UM47 Q9Y274 Q9Y644	ATP2A1 ATP2A2 ATP2A3 ATP2B B4GALT1 CGS23 FUR FURIN GGTB2 INT3 LFNG MFNG NANTA3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PACE PCSK3 RAB6 RAB6A RFNG RNP24 SEL1L SIAT10 SIAT4C SIAT6 ST3GAL3 ST3GAL4 ST3GAL6 STZ TAN1 TMED2 TSA305	Homo sapiens (human)
Gastrin-CREB signalling pathway via PKC and MAPK	Gastrin/cholecystokinin type B receptor Gastrin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3	P01350 P27361 P28482 P32239 P51812 Q13164 Q15349 Q15418	BMK1 CCKBR CCKRB ERK1 ERK2 ERK5 GAS GAST ISPK1 MAPK1 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C PRKM1 PRKM2 PRKM3 PRKM7 RPS6KA1 RPS6KA2 RPS6KA3 RSK1 RSK2 RSK3	Homo sapiens (human)
Homologous DNA Pairing and Strand Exchange	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2 XRCC3	Homo sapiens (human)
Cyclin A/B1/B2 associated events during G2/M transition	CDK-activating kinase assembly factor MAT1 Cyclin-A1 Cyclin-A2 Cyclin-H Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Cyclin-dependent kinase 7 Exportin-1 Forkhead box protein M1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Leucine carboxyl methyltransferase 1 M-phase inducer phosphatase 1 M-phase inducer phosphatase 2 M-phase inducer phosphatase 3 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Protein phosphatase methylesterase 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Wee1-like protein kinase	O14980 O95067 P06493 P14635 P20248 P24941 P30153 P30154 P30291 P30304 P30305 P30307 P50613 P51946 P51948 P53350 P62714 P63151 P67775 P78396 Q08050 Q99640 Q9UIC8 Q9Y570 Q9Y5P8	CAK CAK1 CAP35 CCN1 CCNA CCNA1 CCNA2 CCNB CCNB1 CCNB2 CCNH CDC2 CDC25A CDC25B CDC25C CDC25HU2 CDC28A CDK1 CDK2 CDK7 CDKN1 CDKN2 CDKN7 CRM1 FKHL16 FOXM1 HFH11 LCMT LCMT1 MAT1 MNAT1 MO15 MPP2 MYT1 P34CDC2 PKMYT1 PLK PLK1 PME1 PPME1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R3L RNF66 STK1 WEE1 WIN XPO1	Homo sapiens (human)
Notch-HLH transcription pathway	CREB-binding protein F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Recombining binding protein suppressor of hairless SNW domain-containing protein 1	O15379 O60907 O75376 P46531 P56524 Q04721 Q06330 Q13495 Q13547 Q13573 Q8IZL2 Q8WUI4 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96DB2 Q96JK9 Q99466 Q9BY41 Q9BZK7 Q9UBN7 Q9UKV0 Q9UM47 Q9UQL6 Q9Y618	CBP CG1 CREBBP CTG26 CXorf6 GCN5 GCN5L2 HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP IGKJRB IGKJRB1 INT3 IRA1 KAT2A KAT2B KIAA0200 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 MITR NCOR1 NCOR2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PCAF RBPJ RBPJK RBPSUH RPD3L1 SKIIP SKIP SNW1 TAN1 TBL1 TBL1X TBL1XR1 TBLR1	Homo sapiens (human)
Defective B4GALT1 causes CDG-2d	Beta-1,4-galactosyltransferase 1	P15291	B4GALT1 GGTB2	Homo sapiens (human)
Transcription of E2F targets under negative control by DREAM complex	Cell division control protein 6 homolog DNA topoisomerase 2-alpha Histone deacetylase 1 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 Myc proto-oncogene protein Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Protein max Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P01106 P11388 P12004 P28749 P30304 P61244 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741	BARA BHLHD4 BHLHE39 C14orf46 CDC18L CDC25A CDC6 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MAX MYC PCNA RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS TOP2 TOP2A	Homo sapiens (human)
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin-6 receptor subunit alpha Interleukin-6 Mitogen-activated protein kinase 3 Non-receptor tyrosine-protein kinase TYK2 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O60674 P05231 P06493 P08887 P23458 P27361 P29597 Q02750 Q06124	CDC2 CDC28A CDK1 CDKN1 ERK1 IFNB2 IL6 IL6R JAK1 JAK1A JAK1B JAK2 MAP2K1 MAPK3 MEK1 P34CDC2 PRKM3 PRKMK1 PTP2C PTPN11 SHPTP2 TYK2	Homo sapiens (human)
Insulin receptor signalling cascade	GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Insulin receptor Insulin SHC-transforming protein 1 Son of sevenless homolog 1	P01111 P01112 P01308 P06213 P29353 Q07889 Q13322	GRB10 GRBIR HRAS HRAS1 INS INSR KIAA0207 NRAS SHC SHC1 SHCA SOS1	Homo sapiens (human)
ATF6 (ATF6-alpha) activates chaperone genes	Calreticulin Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-dependent transcription factor ATF-6 alpha DNA damage-inducible transcript 3 protein Endoplasmic reticulum chaperone BiP Endoplasmin Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma	P11021 P14625 P18848 P18850 P23511 P25208 P27797 P35638 Q13952	ATF4 ATF6 CALR CHOP CHOP10 CREB2 CRTC DDIT3 GADD153 GRP78 GRP94 HAP3 HSP90B1 HSPA5 HSPC4 NFYA NFYB NFYC TRA1 TXREB	Homo sapiens (human)
GSD Ia	Glucose-6-phosphatase catalytic subunit 1	P35575	G6PC G6PC1 G6PT	Homo sapiens (human)
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Histone RNA hairpin-binding protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' U7 snRNA-associated Sm-like protein LSm10 U7 snRNA-associated Sm-like protein LSm11 Zinc finger protein 473	P14678 P52298 P62304 P62306 P62308 P62318 P83369 Q09161 Q14493 Q8WTR7 Q969L4	CBP20 CBP80 COD HBP KIAA1141 LSM10 LSM11 NCBP NCBP1 NCBP2 PBSCF PBSCG SLBP SNRPB SNRPB1 SNRPD3 SNRPE SNRPF SNRPG ZFP100 ZNF473	Homo sapiens (human)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 C-type lectin domain family 7 member A Caspase recruitment domain-containing protein 11 Caspase recruitment domain-containing protein 9 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95999 P0CG47 P0CG48 P16885 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43405 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 Q04206 Q05655 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N5C8 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9BXN2 Q9H257 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BGR BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARD9 CARMA1 CDC34 CHUK CIPER CLAP CLEC7A CLECSF12 CROC1 CUL1 DECTIN1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PKCD PLCG2 POH1 PRKCD PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 SYK TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z	Homo sapiens (human)
Defective factor XII causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Prothrombin	P00734 P00748 P03952	F12 F2 KLK3 KLKB1	Homo sapiens (human)
Degradation of GLI1 by the proteasome	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein numb homolog S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P08151 P0CG47 P0CG48 P17612 P17980 P20618 P22612 P22694 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49757 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96J02 Q99436 Q99460 Q9UL46 Q9UMX1 Q9UNM6 Q9Y297	BTRC BTRCP C14orf41 C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GLI GLI1 HC2 HC3 HC8 HC9 HSPC IFI5111 ITCH KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU NUMB OCP2 PFAAP4 PKACA POH1 PRKACA PRKACB PRKACG PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUFU SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of other transcription factors	Cbp/p300-interacting transactivator 2 Pituitary homeobox 2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P05549 Q92754 Q99697 Q99967	AP2TF ARP1 CITED2 MRG1 PITX2 RGS RIEG RIEG1 TFAP2 TFAP2A TFAP2C	Homo sapiens (human)
HHAT G278V doesn't palmitoylate Hh-Np	Desert hedgehog protein Indian hedgehog protein Protein-cysteine N-palmitoyltransferase HHAT Sonic hedgehog protein	O43323 Q14623 Q15465 Q5VTY9	DHH HHAT IHH MART2 SHH SKI1	Homo sapiens (human)
Selenoamino acid metabolism	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase Eukaryotic translation elongation factor 1 epsilon-1 Glutamine--tRNA ligase Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lysine--tRNA ligase Methionine--tRNA ligase, cytoplasmic	O43324 P07814 P14868 P41252 P47897 P54136 P56192 Q12904 Q13155 Q15046 Q9P2J5	AIMP1 AIMP2 AIMP3 DARS DARS1 EEF1E1 EMAP2 EPRS EPRS1 GLNS IARS IARS1 JTV1 KARS KARS1 KIAA0070 KIAA1352 LARS LARS1 MARS MARS1 P18 PARS QARS QARS1 QPRS RARS RARS1 SCYE1	Homo sapiens (human)

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