GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **826 - 850** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine H3 receptor Histamine H4 receptor	P25021 P35367 Q9H3N8 Q9Y5N1	GPCR105 GPCR97 HRH1 HRH2 HRH3 HRH4	Homo sapiens (human)
Histidine catabolism	Carnosine N-methyltransferase Carnosine synthase 1 Formimidoyltransferase-cyclodeaminase Histamine N-methyltransferase Histidine ammonia-lyase Histidine decarboxylase Probable imidazolonepropionase Urocanate hydratase	A5YM72 O95954 P19113 P42357 P50135 Q8N4J0 Q96N76 Q96NU7	AMDHD1 ATPGD1 C9orf41 CARNMT1 CARNS1 FTCD HAL HDC HIS HNMT KIAA1394 UROC1	Homo sapiens (human)
Homologous DNA Pairing and Strand Exchange	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2 XRCC3	Homo sapiens (human)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormone alpha-2 Glycoprotein hormone beta-5 Glycoprotein hormones alpha chain Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin-1 Progonadoliberin-2 Putative gonadotropin-releasing hormone II receptor Thyrotropin receptor Thyrotropin subunit beta	O43555 P01148 P01215 P01222 P01225 P01229 P16473 P22888 P23945 P30968 Q86YW7 Q96P88 Q96T91	CGA FSHB FSHR GNRH GNRH1 GNRH2 GNRHR GNRHR2 GPA2 GPB5 GPHA2 GPHB5 GRH GRHR LCGR LGR1 LGR2 LGR3 LHB LHCGR LHRH LHRHR TSHB TSHR ZLUT1 ZSIG51	Homo sapiens (human)
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A ELAV-like protein 1 Exportin-1 Nuclear pore complex protein Nup214 Protein SET Protein kinase C alpha type Protein kinase C delta type Tumor necrosis factor ligand superfamily member 13	O14980 O75888 P17252 P35658 P39687 Q01105 Q05655 Q15717	ANP32A APRIL C15orf1 CAIN CAN CRM1 ELAVL1 HUR KIAA0023 LANP MAPM NUP214 PHAP1 PKCA PKCD PRKACA PRKCA PRKCD SET TALL2 TNFSF13 XPO1 ZTNF2	Homo sapiens (human)
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration-inducing and hyaluronan-binding protein Hyaluronan synthase 1 Hyaluronan synthase 2 Hyaluronan synthase 3	O00219 O15440 Q8WUJ3 Q92819 Q92839	ABCC5 CEMIP HAS HAS1 HAS2 HAS3 HYBID KIAA1199 MRP5	Homo sapiens (human)	G35674CY
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase-1 Hyaluronidase-2 Hyaluronidase-3 Lymphatic vessel endothelial hyaluronic acid receptor 1 Sodium/hydrogen exchanger 1 Stabilin-2	O43820 O75330 P06865 P07686 P08236 P16070 P19634 Q12794 Q12891 Q8WWQ8 Q99653 Q9Y5Y7	APNH1 CD44 CHP CHP1 CRSBP1 FEEL2 FELL FEX2 GUSB HAR HARE HEXA HEXB HMMR HYAL1 HYAL2 HYAL3 IHABP LHR LUCA1 LUCA2 LUCA3 LYVE1 MDU2 MDU3 MIC4 NHE1 RHAMM SLC9A1 STAB2 XLKD1	Homo sapiens (human)	G35674CY
Hydrolysis of LPC	Cytosolic phospholipase A2 beta Cytosolic phospholipase A2 delta Cytosolic phospholipase A2 epsilon Cytosolic phospholipase A2 gamma Cytosolic phospholipase A2 zeta Cytosolic phospholipase A2 Glycerophosphocholine phosphodiesterase GPCPD1 Lysosomal phospholipase A and acyltransferase Phospholipase B-like 1	P0C869 P47712 Q3MJ16 Q68DD2 Q6P4A8 Q86XP0 Q8NCC3 Q9NPB8 Q9UP65	CPLA2 GDE5 GPCPD1 KIAA1434 LYPLA3 PLA2G15 PLA2G4 PLA2G4A PLA2G4B PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLBD1	Homo sapiens (human)
Hydroxycarboxylic acid-binding receptors	Hydroxycarboxylic acid receptor 1 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor 3	P49019 Q8TDS4 Q9BXC0	GPR104 GPR109A GPR109B GPR81 HCA1 HCA2 HCA3 HCAR1 HCAR2 HCAR3 HM74A HM74B NIACR1 NIACR2	Homo sapiens (human)
Hypusinylation	Deoxyhypusine hydroxylase Deoxyhypusine synthase Eukaryotic translation initiation factor 5A-1 Eukaryotic translation initiation factor 5A-2	P49366 P63241 Q9BU89 Q9GZV4	DHPS DOHH DS EIF5A EIF5A2 HLRC1	Homo sapiens (human)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P01579 P04049 P15260 P23458 P27361 P28482 P38484	ERK1 ERK2 IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 RAF RAF1	Homo sapiens (human)
IKBKB deficiency causes SCID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
IKK complex recruitment mediated by RIP1	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O14920 O15111 P08571 P0CG47 P0CG48 P51668 P61077 P61088 P62837 P62979 P62987 Q13404 Q13489 Q13490 Q13546 Q86XR7 Q8IUC6 Q9Y4K3 Q9Y572 Q9Y6K9 Q9Y6Y9	API1 API2 BIRC2 BIRC3 BLU CD14 CHUK CROC1 ESOP1 FIP3 IKBKB IKBKG IKKA IKKB LY96 MD2 MIHB MIHC NEMO PRVTIRB PUBC1 RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RNF85 RPS27A SFT TCF16 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin-1 Cardiotrophin-like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Cytokine receptor-like factor 1 Interleukin-11 receptor subunit alpha Interleukin-11 Interleukin-31 receptor subunit alpha Interleukin-31 Interleukin-6 receptor subunit beta Leukemia inhibitory factor receptor Leukemia inhibitory factor Non-receptor tyrosine-protein kinase TYK2 Oncostatin-M-specific receptor subunit beta Oncostatin-M Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 O75462 P13725 P15018 P20809 P23458 P26441 P26992 P29597 P40189 P42702 Q14626 Q16619 Q6EBC2 Q8NI17 Q99650 Q9UBD9	BSF3 CLC CLCF1 CNTF CNTFR CRL3 CRLF1 CTF1 GPL HILDA IL11 IL11RA IL31 IL31RA IL6ST JAK1 JAK1A JAK1B JAK2 LIF LIFR NNT1 OSM OSMR OSMRB TYK2	Homo sapiens (human)
IRAK1 recruits IKK complex	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43187 O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q9NYJ8 Q9Y4K3	IRAK2 KIAA0733 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
IRAK4 deficiency (TLR2/4)	Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Interleukin-1 receptor-associated kinase 4 Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P58753 Q06187 Q15399 Q99836 Q9NWZ3 Q9Y2C9 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 IRAK4 KIAA0012 LY96 MAL MD2 MRP14 MRP8 MYD88 S100A S100A1 S100A8 S100A9 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 mip porB	Homo sapiens (human)
IRAK4 deficiency (TLR5)	Flagellin Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 Toll-like receptor 10 Toll-like receptor 5	O60602 P04949 Q99836 Q9BXR5 Q9NWZ3	IRAK4 MYD88 TIL3 TLR10 TLR5 flaF fliC hag	Homo sapiens (human)
IRE1alpha activates chaperones	Endoplasmic reticulum chaperone BiP Serine/threonine-protein kinase/endoribonuclease IRE1	O75460 P11021	ERN1 GRP78 HSPA5 IRE1	Homo sapiens (human)
IRF3 mediated activation of type 1 IFN	E3 ubiquitin-protein ligase DTX4 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Serine/threonine-protein kinase TBK1 Z-DNA-binding protein 1	Q14653 Q96MN2 Q9H171 Q9UHD2 Q9Y2E6	C20orf183 DLM1 DTX4 IRF3 KIAA0937 NAK NALP4 NLRP4 PAN2 PYPAF4 RNF155 RNH2 TBK1 ZBP1	Homo sapiens (human)
IRF3-mediated induction of type I IFN	DNA-dependent protein kinase catalytic subunit Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase DTX4 Gamma-interferon-inducible protein 16 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 NLR family CARD domain-containing protein 3 Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Three-prime repair exonuclease 1 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	P12956 P13010 P49959 P78527 Q14653 Q16666 Q7RTR2 Q86WV6 Q96MN2 Q9NSU2 Q9UHD2 Q9UJV9 Q9Y2E6	ABS DDX41 DTX4 ERIS G22P1 G22P2 HNGS1 HYRC HYRC1 IFI16 IFNGIP1 IRF3 KIAA0937 MITA MRE11 MRE11A NAK NALP4 NLRC3 NLRP4 NOD3 PAN2 PRKDC PYPAF4 RNF155 RNH2 STING STING1 TBK1 TMEM173 TREX1 XRCC5 XRCC6	Homo sapiens (human)
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin	P01308 P06213 P35568 Q13322 Q9Y4H2	GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207	Homo sapiens (human)

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