GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **826 - 850** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Defective CUBN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)
Defective factor XII causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Prothrombin	P00734 P00748 P03952	F12 F2 KLK3 KLKB1	Homo sapiens (human)
Defective SERPING1 causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Plasma protease C1 inhibitor	P00748 P03952 P05155	C1IN C1NH F12 KLK3 KLKB1 SERPING1	Homo sapiens (human)
Defective F8 accelerates dissociation of the A2 domain	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 binding to the cell membrane	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 secretion	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 binding to von Willebrand factor	Coagulation factor VIII von Willebrand factor	P00451 P04275	F8 F8C F8VWF VWF	Homo sapiens (human)
Defective F8 cleavage by thrombin	Coagulation factor VIII Prothrombin von Willebrand factor	P00451 P00734 P04275	F2 F8 F8C F8VWF VWF	Homo sapiens (human)
Defective F8 sulfation at Y1699	Coagulation factor VIII Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 P00451	F8 F8C TPST1 TPST2	Homo sapiens (human)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Fructosamine-3-kinase Ketosamine-3-kinase Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 O60725 P00451 Q9H479 Q9HA64	F8 F8C FN3K FN3KRP ICMT PCCMT TPST1 TPST2	Homo sapiens (human)
Defective F9 secretion	Coagulation factor IX	P00740	F9	Homo sapiens (human)
Defective gamma-carboxylation of F9	Coagulation factor IX Vitamin K-dependent gamma-carboxylase	P00740 P38435	F9 GC GGCX	Homo sapiens (human)
Defective F9 activation	Coagulation factor IX Coagulation factor XI Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V	P00740 P03951 P07359 P13224 P14770 P40197	F11 F9 GP1BA GP1BB GP5 GP9	Homo sapiens (human)
Defective cofactor function of FVIIIa variant	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective F9 variant does not activate FX	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective factor IX causes thrombophilia	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	P00740 P00742 P08709 P10646 P13726	F10 F3 F7 F9 LACI TFPI TFPI1	Homo sapiens (human)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P22891 Q14393	AXLLG BGLAP F10 F2 F7 F9 GAS6 PROC PROS PROS1 PROZ	Homo sapiens (human)
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P22891 P38435 Q14393	AXLLG BGLAP F10 F2 F7 F9 GAS6 GC GGCX PROC PROS PROS1 PROZ	Homo sapiens (human)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Furin Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P09958 P22891 Q14393	AXLLG BGLAP F10 F2 F7 F9 FUR FURIN GAS6 PACE PCSK3 PROC PROS PROS1 PROZ	Homo sapiens (human)
Intraflagellar transport	Clusterin-associated protein 1 Cytoplasmic dynein 2 heavy chain 1 Cytoplasmic dynein 2 intermediate chain 1 Cytoplasmic dynein 2 intermediate chain 2 Cytoplasmic dynein 2 light intermediate chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light chain Tctex-type 5 Dynein light chain Tctex-type protein 2 Dynein light chain Tctex-type protein 2B Dynein light chain roadblock-type 1 Dynein light chain roadblock-type 2 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 20 homolog Intraflagellar transport protein 22 homolog Intraflagellar transport protein 25 homolog Intraflagellar transport protein 27 homolog Intraflagellar transport protein 43 homolog Intraflagellar transport protein 46 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 56 Intraflagellar transport protein 57 homolog Intraflagellar transport protein 70A Intraflagellar transport protein 70B Intraflagellar transport protein 74 homolog Intraflagellar transport protein 80 homolog Intraflagellar transport protein 81 homolog Intraflagellar transport protein 88 homolog Kinesin-associated protein 3 Kinesin-like protein KIF17 Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C TRAF3-interacting protein 1 Tetratricopeptide repeat protein 21B Thyroid receptor-interacting protein 11 Transportin-1 WD repeat-containing protein 19 WD repeat-containing protein 35	A0AVF1 O14782 O15066 P63167 Q13099 Q15643 Q7Z4L5 Q86WT1 Q8IY31 Q8IZS6 Q8N4P2 Q8N7M0 Q8NCM8 Q8NEZ3 Q8TCX1 Q8TDR0 Q8TF09 Q8WVS4 Q8WW35 Q8WYA0 Q92845 Q92973 Q96AJ1 Q96EX3 Q96FJ2 Q96FT9 Q96LB3 Q96RY7 Q9BW83 Q9H7X7 Q9HBG6 Q9NP97 Q9NQC8 Q9NWB7 Q9P2E2 Q9P2H3 Q9P2L0 Q9UG01 Q9Y366 Q9Y496 Q9Y547	BITH C11orf2 C11orf60 C14orf179 C1orf41 C20orf9 CCDC2 CDV1 CEV14 CLUAP1 CMG1 D2LIC DERP8 DHC1B DHC2 DLC1 DLC2 DNCH2 DNCL1 DNCL2A DNCL2B DNCLC1 DNLC2A DNLC2B DYH1B DYNC2H1 DYNC2I1 DYNC2I2 DYNC2LI1 DYNLL1 DYNLL2 DYNLRB1 DYNLRB2 DYNLT2 DYNLT2B DYNLT5 ESRRBL1 HDLC1 HIPPI HSPB11 IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT20 IFT22 IFT25 IFT27 IFT43 IFT46 IFT52 IFT54 IFT56 IFT57 IFT70A IFT70B IFT74 IFT80 IFT81 IFT88 KIAA0359 KIAA0590 KIAA0643 KIAA1179 KIAA1336 KIAA1374 KIAA1405 KIAA1638 KIAA1992 KIAA1997 KIF17 KIF3 KIF3A KIF3AP KIF3B KIF3C KIF3X KIFAP3 KPNB2 LIC3 MIP1 MIPT3 NGD5 RABL4 RABL5 RAYL ROBLD1 ROBLD2 SMAP SPG TCTE3 TCTEX1D1 TCTEX1D2 TCTEX1D3 TG737 TNPO1 TRAF3IP1 TRIP11 TRN TTC10 TTC21B TTC26 TTC30A TTC30B WDR10 WDR140 WDR19 WDR34 WDR35 WDR56 WDR60 WDTC2	Homo sapiens (human)
Terminal pathway of complement	Clusterin Complement C5 Complement component C6 Complement component C7 Complement component C8 alpha chain Complement component C8 beta chain Complement component C8 gamma chain Complement component C9	P01031 P02748 P07357 P07358 P07360 P10643 P10909 P13671	APOJ C5 C6 C7 C8A C8B C8G C9 CLI CLU CPAMD4 KUB1	Homo sapiens (human)
Inhibition of Host mRNA Processing and RNA Silencing	Cleavage and polyadenylation specificity factor subunit 4 Non-structural protein 1 Polyadenylate-binding protein 2	O95639 P03496 Q86U42	CPSF30 CPSF4 NAR NEB1 NS PAB2 PABP2 PABPN1	Homo sapiens (human)
Processing of Intronless Pre-mRNAs	Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Symplekin pre-mRNA 3' end processing protein WDR33	O43809 O94913 O95639 P33240 P51003 P52298 Q05048 Q09161 Q10570 Q12996 Q6UN15 Q86U42 Q8N684 Q92797 Q92989 Q9C0J8 Q9H0L4 Q9P2I0 Q9UKF6	CBP20 CBP80 CFIM25 CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 FIP1 FIP1L1 HEAB KIAA0689 KIAA0824 KIAA1367 NAR NCBP NCBP1 NCBP2 NEB1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCF11 RHE SPK SYMPK WDC146 WDR33	Homo sapiens (human)
Processing of Capped Intron-Containing Pre-mRNA	Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3 Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein M Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Heterogeneous nuclear ribonucleoproteins C1/C2 N6-adenosine-methyltransferase catalytic subunit N6-adenosine-methyltransferase non-catalytic subunit Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Poly(rC)-binding protein 1 Poly(rC)-binding protein 2 Polyadenylate-binding protein 2 Polypyrimidine tract-binding protein 1 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-splicing regulator WTAP RNA-binding motif protein, X chromosome RNA-binding protein 10 RNA-binding protein FUS Serine/arginine-rich splicing factor 10 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 12 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 8 Serine/arginine-rich splicing factor 9 Symplekin Transformer-2 protein homolog beta Y-box-binding protein 1 pre-mRNA 3' end processing protein WDR33	O15514 O43390 O43809 O75494 O94913 O95639 P07910 P09651 P13984 P14866 P19387 P19388 P22626 P24928 P26599 P30876 P31943 P33240 P35269 P35637 P36954 P38159 P51003 P51991 P52272 P52298 P52434 P52435 P52597 P53803 P55795 P61218 P61978 P62487 P62875 P62995 P67809 P84103 P98175 Q00839 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q14103 Q15007 Q15365 Q15366 Q16629 Q6UN15 Q86U42 Q86U44 Q8N684 Q8WXF0 Q92797 Q92989 Q9BRL6 Q9C0J8 Q9H0L4 Q9HCE5 Q9P2I0 Q9UKF6	ASF AUF1 C1orf199 CBP20 CBP80 CFIM25 CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 DXS8237E FIP1 FIP1L1 FTP3 FUS FUSIP1 FUSIP2 GPATC9 GPATCH9 GTF2F1 GTF2F2 HEAB HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HNRNPU HNRPA1 HNRPA2B1 HNRPA3 HNRPC HNRPD HNRPF HNRPG HNRPH HNRPH1 HNRPH2 HNRPK HNRPL HNRPM HNRPR HNRPU HRS KIAA0105 KIAA0122 KIAA0689 KIAA0824 KIAA1367 KIAA1627 METTL14 METTL3 MTA70 NAGR1 NAR NCBP NCBP1 NCBP2 NEB1 NSEP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCBP1 PCBP2 PCF11 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PTB PTBP1 RAP30 RAP74 RBM10 RBMX RBMXP1 RHE RPB7 SAFA SF2 SF2P33 SFRS1 SFRS10 SFRS11 SFRS13A SFRS13B SFRS19 SFRS2 SFRS2B SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SPK SRP20 SRP30C SRP40 SRP46 SRP55 SRP75 SRRP35 SRSF1 SRSF10 SRSF11 SRSF12 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 SYMPK TASR TLS TRA2B U21.1 WDC146 WDR33 WTAP YB1 YBX1	Homo sapiens (human)

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