GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **876 - 900** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
HDMs demethylate histones	AT-rich interactive domain-containing protein 5B Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Histone H3.1 Histone H3.2 Histone H4 Histone demethylase UTY Histone lysine demethylase PHF8 Lysine-specific demethylase 2A Lysine-specific demethylase 2B Lysine-specific demethylase 3A Lysine-specific demethylase 3B Lysine-specific demethylase 4A Lysine-specific demethylase 4B Lysine-specific demethylase 4C Lysine-specific demethylase 4D Lysine-specific demethylase 5A Lysine-specific demethylase 5B Lysine-specific demethylase 5C Lysine-specific demethylase 5D Lysine-specific demethylase 6A Lysine-specific demethylase 6B Lysine-specific demethylase 7A Lysine-specific demethylase PHF2 Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Ribosomal oxygenase 2	O14607 O15054 O15550 O60341 O75151 O75164 O94953 P29375 P41229 P62805 P68431 Q14865 Q6B0I6 Q6NYC1 Q6ZMT4 Q71DI3 Q7LBC6 Q8IUF8 Q8NB78 Q8NHM5 Q9BY66 Q9H3R0 Q9UGL1 Q9UPP1 Q9Y2K7 Q9Y4C1	AOF1 AOF2 ARID5B C5orf7 C6orf193 CENP-35 CXXC2 CXXC8 DESRT DXS1272E FBL10 FBL11 FBL7 FBXL10 FBXL11 GASC1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST4H4 HY HYA JARID1A JARID1B JARID1C JARID1D JHDM1A JHDM1B JHDM1D JHDM2A JHDM2B JHDM3A JHDM3B JHDM3C JHDM3D JMJD1 JMJD1A JMJD1B JMJD2 JMJD2A JMJD2B JMJD2C JMJD2D JMJD3 JMJD6 KDM1 KDM1A KDM1B KDM2A KDM2B KDM3A KDM3B KDM4A KDM4B KDM4C KDM4D KDM5A KDM5B KDM5C KDM5D KDM6A KDM6B KDM6C KDM7 KDM7A KIAA0234 KIAA0346 KIAA0585 KIAA0601 KIAA0662 KIAA0677 KIAA0742 KIAA0780 KIAA0876 KIAA1004 KIAA1082 KIAA1111 KIAA1718 LSD1 LSD2 MDIG MINA MINA53 MRF2 NDY1 NO52 PCCX2 PHF2 PHF8 PLU1 PSR PTDSR RBBP2 RBBP2H1 RBP2 RIOX2 SMCX SMCY TSGA UTX UTY XE169 ZNF422	Homo sapiens (human)
Response to elevated platelet cytosolic Ca2+	Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type	P05129 P05771 P17252	PKCA PKCB PKCG PRKACA PRKCA PRKCB PRKCB1 PRKCG	Homo sapiens (human)
Metalloprotease DUBs	26S proteasome non-ATPase regulatory subunit 14 AMSH-like protease BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 BRISC complex subunit Abraxas 2 Breast cancer type 1 susceptibility protein Deubiquitinase MYSM1 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone acetyltransferase KAT2B Histone acetyltransferase p300 Lys-63-specific deubiquitinase BRCC36 NACHT, LRR and PYD domains-containing protein 3 Polyubiquitin-B Polyubiquitin-C STAM-binding protein Signal transducing adapter molecule 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00487 O95630 P04908 P0C0S8 P0CG47 P0CG48 P20671 P38398 P46736 P62979 P62987 Q09472 Q15018 Q16777 Q5VVJ2 Q6FI13 Q6UWZ7 Q7L7L0 Q8IUE6 Q92783 Q92831 Q93077 Q96FJ0 Q96KK5 Q96P20 Q96QV6 Q96RL1 Q99728 Q99878 Q9NWV8 Q9NXR7	ABRA1 ABRAXAS1 ABRAXAS2 ABRO1 AMSH AMSHLP BABAM1 BABAM2 BARD1 BRCA1 BRCC3 BRCC36 BRCC45 BRE C19orf62 C1orf7 C6.1A CCDC98 CIAS1 CXorf53 EP300 FAM175A FAM175B H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST3H2A KAT2B KIAA0157 KIAA1373 KIAA1915 MERIT40 MYSM1 NALP3 NBA1 NLRP3 P300 PCAF POH1 PSMD14 PYPAF1 RAP80 RNF53 RPS27A RXRIP110 STAM STAM1 STAMBP STAMBPL1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UIMC1	Homo sapiens (human)
Insulin receptor recycling	Cathepsin D Insulin receptor Insulin-degrading enzyme Insulin Receptor-type tyrosine-protein phosphatase F Tyrosine-protein phosphatase non-receptor type 1 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2	O15342 O75348 O95670 P01308 P06213 P07339 P10586 P14735 P15313 P18031 P21281 P21283 P27449 P36543 P38606 P61421 Q13488 Q15904 Q16864 Q8N8Y2 Q8NEY4 Q8NHE4 Q93050 Q96A05 Q96LB4 Q99437 Q9HBG4 Q9UI12 Q9Y487 Q9Y5K8	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6IP1 ATP6J ATP6L ATP6M ATP6N1 ATP6N1A ATP6N1B ATP6N1C ATP6N2 ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A3 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL C7orf32 CPSD CTSD IDE INS INSR LAR NG38 PTP1B PTPN1 PTPRF TCIRG1 VATB VATC VATD VATF VATPS1 VPATPD VPP1 VPP2 VPP3 XAP3	Homo sapiens (human)
Defective CD320 causes MMATC	CD320 antigen Transcobalamin-2	P20062 Q9NPF0	8D6A CD320 TC2 TCN2	Homo sapiens (human)
Serine biosynthesis	D-3-phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase Serine incorporator 1 Serine incorporator 2 Serine incorporator 3 Serine incorporator 4 Serine incorporator 5 Serine racemase	A6NH21 O43175 P78330 Q13530 Q86VE9 Q96SA4 Q9GZT4 Q9NRX5 Q9Y617	C5orf12 DIFF33 KIAA1253 PGDH3 PHGDH PSA PSAT1 PSPH SERINC1 SERINC2 SERINC3 SERINC4 SERINC5 SRR TDE1 TDE1L TDE2 TDE2L	Homo sapiens (human)
Transfer of LPS from LBP carrier to CD14	Lipopolysaccharide-binding protein Monocyte differentiation antigen CD14	P08571 P18428	CD14 LBP	Homo sapiens (human)
ROS and RNS production in phagocytes	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Natural resistance-associated macrophage protein 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Nitric oxide synthase 1 Nitric oxide synthase 3 Nitric oxide synthase, inducible Ras-related C3 botulinum toxin substrate 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2 Voltage-gated hydrogen channel 1	O15342 O75348 O95670 P04839 P13498 P14598 P15153 P15313 P19878 P21281 P21283 P27449 P29474 P29475 P35228 P36543 P38606 P49279 P61421 Q13488 Q15080 Q16864 Q8N8Y2 Q8NEY4 Q8NHE4 Q93050 Q96A05 Q96D96 Q96LB4 Q99437 Q9HBG4 Q9UI12 Q9Y487 Q9Y5K8	ATP6A1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6J ATP6L ATP6M ATP6N1 ATP6N1A ATP6N1B ATP6N1C ATP6N2 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A3 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL C7orf32 CYBA CYBB HVCN1 LSH NCF1 NCF2 NCF4 NG38 NOS1 NOS2 NOS2A NOS3 NOX2 NOXA2 NOXO2 NRAMP NRAMP1 P67PHOX RAC2 SH3PXD1A SH3PXD4 SLC11A1 TCIRG1 VATB VATC VATD VATF VPATPD VPP1 VPP2 VPP3 VSOP	Homo sapiens (human)
Aberrant regulation of mitotic exit in cancer due to RB1 defects	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Retinoblastoma-associated protein S-phase kinase-associated protein 2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06400 P30260 P51668 P51965 P60006 Q13042 Q13309 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E E2EPF FBXL1 FYR FZR FZR1 KIAA1242 KIAA1406 RB1 SFT SKP2 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Regulation of PTEN localization	E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase XIAP Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Protein PML Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P29590 P46934 P60484 P62979 P62987 P98170 Q93009	API3 BIRC4 HAUSP IAP3 KIAA0093 MMAC1 MYL NEDD4 NEDD4-1 PML PP8675 PTEN RNF71 RPF1 RPS27A TEP1 TRIM19 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 XIAP	Homo sapiens (human)
STAT6-mediated induction of chemokines	Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 6 Stimulator of interferon genes protein	P42226 Q86WV6 Q9UHD2	ERIS MITA NAK STAT6 STING STING1 TBK1 TMEM173	Homo sapiens (human)
Translesion Synthesis by POLH	DNA polymerase eta DNA-dependent metalloprotease SPRTN Nuclear protein localization protein 4 homolog Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RING finger and CHY zinc finger domain-containing protein 1 Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transitional endoplasmic reticulum ATPase Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P12004 P15927 P27694 P35244 P35249 P35250 P35251 P40937 P40938 P55072 P62979 P62987 Q8TAT6 Q92890 Q96PM5 Q9H040 Q9Y253	ARNIP C1orf124 CHIMP DVC1 HEL-220 HEL-S-70 KIAA1499 NPL4 NPLOC4 PCNA PIRH2 POLH RAD30 RAD30A RCHY1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF199 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SPRTN UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UFD1 UFD1L VCP XPV ZNF363	Homo sapiens (human)
Purine ribonucleoside monophosphate biosynthesis	Adenylosuccinate lyase Adenylosuccinate synthetase isozyme 1 Adenylosuccinate synthetase isozyme 2 Amidophosphoribosyltransferase Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Bifunctional purine biosynthesis protein ATIC GMP synthase [glutamine-hydrolyzing] Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Phosphoribosylformylglycinamidine synthase Trifunctional purine biosynthetic protein adenosine-3	O15067 P12268 P20839 P22102 P22234 P30520 P30566 P31939 P49915 Q06203 Q8N142	ADE2 ADSL ADSS ADSS1 ADSS2 ADSSL1 AIRC AMPS ATIC GART GMPS GPAT IMPD1 IMPD2 IMPDH1 IMPDH2 KIAA0361 PAICS PAIS PFAS PGFT PPAT PRGS PURH	Homo sapiens (human)
Regulation of PAK-2p34 activity by PS-GAP/RHG10	Rho GTPase-activating protein 10 Serine/threonine-protein kinase PAK 2	A1A4S6 Q13177	ARHGAP10 GRAF2 PAK2	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
Attenuation phase	CREB-binding protein DnaJ homolog subfamily B member 1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor protein 1 Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Histone acetyltransferase p300 Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3	O75506 P07900 P08238 P0DMV8 P0DMV9 P11142 P25685 P34931 P54652 Q00613 Q02790 Q09472 Q15185 Q92793	CBP CREBBP DNAJ1 DNAJB1 EP300 FKBP4 FKBP52 HDJ1 HSBP1 HSC70 HSF1 HSF1BP HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSTF1 HSX70 P23 P300 PTGES3 TEBP	Homo sapiens (human)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase delta Diacylglycerol kinase epsilon Diacylglycerol kinase eta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase kappa Diacylglycerol kinase theta Diacylglycerol kinase zeta Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O75912 O95267 P23743 P24723 P49619 P52429 P52824 Q02156 Q04759 Q05655 Q13507 Q13574 Q14571 Q14573 Q14643 Q16760 Q5KSL6 Q7LDG7 Q86XP1 Q9HCX4 Q9Y210 Q9Y6T7	CDC25L DAGK DAGK1 DAGK2 DAGK3 DAGK4 DAGK5 DAGK6 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKK DGKQ DGKZ INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0145 KIAA0718 MCG7 PKCD PKCE PKCL PRKCD PRKCE PRKCH PRKCL PRKCQ PRKCT RASGRP RASGRP1 RASGRP2 TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
Pre-NOTCH Processing in Golgi	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Beta-1,3-N-acetylglucosaminyltransferase manic fringe Beta-1,3-N-acetylglucosaminyltransferase radical fringe Beta-1,4-galactosyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Furin Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein sel-1 homolog 1 Ras-related protein Rab-6A Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Transmembrane emp24 domain-containing protein 2 Type 2 lactosamine alpha-2,3-sialyltransferase	O00587 O14983 P09958 P15291 P16615 P20340 P46531 Q04721 Q11203 Q11206 Q15363 Q8NES3 Q93084 Q99466 Q9UBV2 Q9UM47 Q9Y274 Q9Y644	ATP2A1 ATP2A2 ATP2A3 ATP2B B4GALT1 CGS23 FUR FURIN GGTB2 INT3 LFNG MFNG NANTA3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PACE PCSK3 RAB6 RAB6A RFNG RNP24 SEL1L SIAT10 SIAT4C SIAT6 ST3GAL3 ST3GAL4 ST3GAL6 STZ TAN1 TMED2 TSA305	Homo sapiens (human)
Gastrin-CREB signalling pathway via PKC and MAPK	Gastrin/cholecystokinin type B receptor Gastrin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3	P01350 P27361 P28482 P32239 P51812 Q13164 Q15349 Q15418	BMK1 CCKBR CCKRB ERK1 ERK2 ERK5 GAS GAST ISPK1 MAPK1 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C PRKM1 PRKM2 PRKM3 PRKM7 RPS6KA1 RPS6KA2 RPS6KA3 RSK1 RSK2 RSK3	Homo sapiens (human)
Homologous DNA Pairing and Strand Exchange	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2 XRCC3	Homo sapiens (human)
Cyclin A/B1/B2 associated events during G2/M transition	CDK-activating kinase assembly factor MAT1 Cyclin-A1 Cyclin-A2 Cyclin-H Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Cyclin-dependent kinase 7 Exportin-1 Forkhead box protein M1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Leucine carboxyl methyltransferase 1 M-phase inducer phosphatase 1 M-phase inducer phosphatase 2 M-phase inducer phosphatase 3 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Protein phosphatase methylesterase 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Wee1-like protein kinase	O14980 O95067 P06493 P14635 P20248 P24941 P30153 P30154 P30291 P30304 P30305 P30307 P50613 P51946 P51948 P53350 P62714 P63151 P67775 P78396 Q08050 Q99640 Q9UIC8 Q9Y570 Q9Y5P8	CAK CAK1 CAP35 CCN1 CCNA CCNA1 CCNA2 CCNB CCNB1 CCNB2 CCNH CDC2 CDC25A CDC25B CDC25C CDC25HU2 CDC28A CDK1 CDK2 CDK7 CDKN1 CDKN2 CDKN7 CRM1 FKHL16 FOXM1 HFH11 LCMT LCMT1 MAT1 MNAT1 MO15 MPP2 MYT1 P34CDC2 PKMYT1 PLK PLK1 PME1 PPME1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R3L RNF66 STK1 WEE1 WIN XPO1	Homo sapiens (human)
Notch-HLH transcription pathway	CREB-binding protein F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Recombining binding protein suppressor of hairless SNW domain-containing protein 1	O15379 O60907 O75376 P46531 P56524 Q04721 Q06330 Q13495 Q13547 Q13573 Q8IZL2 Q8WUI4 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96DB2 Q96JK9 Q99466 Q9BY41 Q9BZK7 Q9UBN7 Q9UKV0 Q9UM47 Q9UQL6 Q9Y618	CBP CG1 CREBBP CTG26 CXorf6 GCN5 GCN5L2 HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP IGKJRB IGKJRB1 INT3 IRA1 KAT2A KAT2B KIAA0200 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 MITR NCOR1 NCOR2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PCAF RBPJ RBPJK RBPSUH RPD3L1 SKIIP SKIP SNW1 TAN1 TBL1 TBL1X TBL1XR1 TBLR1	Homo sapiens (human)
Defective B4GALT1 causes CDG-2d	Beta-1,4-galactosyltransferase 1	P15291	B4GALT1 GGTB2	Homo sapiens (human)
Transcription of E2F targets under negative control by DREAM complex	Cell division control protein 6 homolog DNA topoisomerase 2-alpha Histone deacetylase 1 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 Myc proto-oncogene protein Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Protein max Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P01106 P11388 P12004 P28749 P30304 P61244 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741	BARA BHLHD4 BHLHE39 C14orf46 CDC18L CDC25A CDC6 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MAX MYC PCNA RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS TOP2 TOP2A	Homo sapiens (human)

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