Kinesins
|
|
|
- ATSV
- C20orf23
- C2orf20
- C6orf102
- CENPE
- EG5
- GAKIN
- HSET
- KIAA0359
- KIAA0449
- KIAA0591
- KIAA0639
- KIAA0706
- KIAA1236
- KIAA1448
- KIAA1478
- KIAA1590
- KIAA1708
- KID
- KIF11
- KIF12
- KIF13B
- KIF15
- KIF16B
- KIF18A
- KIF18B
- KIF19
- KIF1A
- KIF1B
- KIF1C
- KIF2
- KIF20A
- KIF20B
- KIF21A
- KIF21B
- KIF22
- KIF23
- KIF25
- KIF26A
- KIF26B
- KIF27
- KIF28P
- KIF2A
- KIF2B
- KIF2C
- KIF3
- KIF3A
- KIF3AP
- KIF3B
- KIF3C
- KIF4
- KIF4A
- KIF4B
- KIF5A
- KIF5B
- KIF5C
- KIF6
- KIF9
- KIFAP3
- KIFC1
- KIFC2
- KLC
- KLC1
- KLC2
- KLC2L
- KLC3
- KLC4
- KLP2
- KLP6
- KNS
- KNS1
- KNS2
- KNSL1
- KNSL2
- KNSL3
- KNSL4
- KNSL5
- KNSL6
- KNSL7
- KNSL8
- KRMP1
- MGCRACGAP
- MKLP1
- MKLP2
- MPHOSPH1
- NKHC1
- RAB6KIFL
- RACGAP1
- SMAP
- SNX23
- TRIP5
|
Homo sapiens (human)
|
|
Polo-like kinase mediated events
|
|
|
- BARA
- BMYB
- C14orf46
- CCNB
- CCNB1
- CCNB2
- CDC25A
- CDC25C
- CENPF
- CXCDC1
- EP300
- FKHL16
- FOXM1
- HFH11
- KIAA2037
- LIN37
- LIN52
- LIN54
- LIN9
- MPP2
- MYBL2
- MYT1
- P300
- PKMYT1
- PLK
- PLK1
- RBAP48
- RBBP4
- TGS
- WEE1
- WIN
|
Homo sapiens (human)
|
|
Deposition of new CENPA-containing nucleosomes at the centromere
|
|
|
- APITD1
- C14orf106
- C16orf56
- C16orf60
- C1orf155
- C21orf45
- C21orf46
- C22orf18
- C6orf139
- C6orf173
- CASC5
- CENPA
- CENPC
- CENPC1
- CENPH
- CENPI
- CENPK
- CENPL
- CENPM
- CENPN
- CENPO
- CENPP
- CENPQ
- CENPR
- CENPS
- CENPT
- CENPU
- CENPW
- CENPX
- CUG2
- FAAP10
- FAAP16
- FAKTS
- FASP1
- FLEG1
- FSHPRH1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HBXAP
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- HJURP
- ICEN19
- ICEN22
- ICEN24
- ICEN32
- ICEN33
- ICEN35
- ICEN36
- ICEN37
- ICEN39
- ICEN7
- INO80H
- ITGB3BP
- KIAA1570
- KIAA1903
- KLIP1
- KNL1
- KNL2
- LRPR1
- M18BP1
- MCM21R
- MHF1
- MHF2
- MIS18A
- MIS18B
- MIS18BP1
- MLF1IP
- NMP238
- NPM
- NPM1
- NRIF3
- OIP5
- PANE1
- PBIP1
- RBAP46
- RBAP48
- RBBP4
- RBBP7
- RSF1
- RUVBL1
- SMARCA5
- SNF2H
- STRA13
- TIP49
- TIP49A
- TSH2B
- URLC9
- WCRF135
- XAP8
|
Homo sapiens (human)
|
|
Loss of function of TP53 in cancer due to loss of tetramerization ability
|
|
|
|
Homo sapiens (human)
|
|
Activation of NOXA and translocation to mitochondria
|
|
|
- DP1
- DP2
- E2F1
- NOXA
- P53
- PMAIP1
- RBBP3
- TFDP1
- TFDP2
- TP53
|
Homo sapiens (human)
|
|
Regulation of TP53 Expression
|
|
|
|
Homo sapiens (human)
|
|
Stabilization of p53
|
|
|
- ATM
- C20orf104
- CDKN2
- CDKN2A
- CDS1
- CHEK2
- CHK2
- GLEA2
- HCA58
- MDM2
- MDM4
- MDMX
- MLM
- NZF
- P53
- PHF20
- RAD53
- RPS27A
- TP53
- TZP
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
Homo sapiens (human)
|
|
Regulation of TP53 Activity through Methylation
|
|
|
- ATM
- BAT8
- C5orf35
- C6orf30
- CDS1
- CHEK2
- CHK2
- EHMT1
- EHMT2
- EP300
- EUHMTASE1
- G9A
- GLP
- HRMT1L5
- IBP72
- JBP1
- JMY
- KIAA0681
- KIAA1876
- KMT1C
- KMT1D
- KMT3C
- KMT5A
- L3MBT
- L3MBTL
- L3MBTL1
- MDM2
- MDM4
- MDMX
- NG36
- P300
- P53
- PRMT5
- PRSET7
- RAD53
- RPS27A
- SET07
- SET8
- SETD8
- SETD9
- SKB1
- SMYD2
- TP53
- TTC5
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
Homo sapiens (human)
|
|
SUMOylation of transcription factors
|
|
|
- BHLHE32
- CDKN2
- CDKN2A
- DDXBP1
- FOXL2
- HIC1
- MDM2
- MITF
- MLM
- MTA1
- P53
- PIAS1
- PIAS3
- PIAS4
- PIASG
- SMT3A
- SMT3B
- SMT3C
- SMT3H1
- SMT3H2
- SMT3H3
- SP3
- SUMO1
- SUMO2
- SUMO3
- TFAP2B
- TFAP2C
- TP53
- TP53BP1
- UBC9
- UBCE9
- UBE2I
- UBL1
- ZBTB29
|
Homo sapiens (human)
|
|
PI5P Regulates TP53 Acetylation
|
|
|
- C14orf9
- EP300
- ING1L
- ING2
- MAP2K6
- MEK6
- MKK6
- P300
- P53
- PI5P4KA
- PIN1
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP4P1
- PIP5K2
- PIP5K2A
- PIP5K2B
- PIP5K2C
- PRKMK6
- SKK3
- TMEM55B
- TP53
|
Homo sapiens (human)
|
|
Transcriptional activation of cell cycle inhibitor p21
|
|
|
- CAP20
- CDKN1
- CDKN1A
- CIP1
- HZF
- MDA6
- P53
- PCBP4
- PIC1
- RZF
- SDI1
- TP53
- WAF1
- ZNF385
- ZNF385A
|
Homo sapiens (human)
|
|
RUNX3 regulates CDKN1A transcription
|
|
|
- AML2
- ATBF1
- C16orf47
- CAP20
- CBFA3
- CDKN1
- CDKN1A
- CIP1
- DPC4
- MADH3
- MADH4
- MDA6
- P53
- PEBP2A3
- PIC1
- RUNX3
- SDI1
- SMAD3
- SMAD4
- TGFB
- TGFB1
- TP53
- WAF1
- ZFHX3
|
Homo sapiens (human)
|
|
Oncogene Induced Senescence
|
|
|
- AGO1
- AGO3
- AGO4
- BHLHB24
- CAGH26
- CDK4
- CDK6
- CDKN2
- CDKN2A
- CDKN2B
- CDKN2C
- CDKN2D
- CDKN6
- DP1
- DP2
- E2F1
- E2F2
- E2F3
- EIF2C1
- EIF2C3
- EIF2C4
- ERF
- ERK1
- ERK2
- ETS1
- ETS2
- EWSR2
- ID
- ID1
- KIAA0075
- KIAA1093
- KIAA1460
- KIAA1567
- KIAA1582
- KIAA1631
- MAPK1
- MAPK3
- MDM2
- MDM4
- MDMX
- MLM
- MOV10
- MTS1
- MTS2
- P53
- PRKM1
- PRKM2
- PRKM3
- RB1
- RBBP3
- RPS27A
- SP1
- TFDP1
- TFDP2
- TNRC6
- TNRC6A
- TNRC6B
- TNRC6C
- TP53
- TSFP1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
Homo sapiens (human)
|
|
Oxidative Stress Induced Senescence
|
|
|
- AGO1
- AGO3
- AGO4
- ASK1
- B55
- BAP1
- BMI1
- CAGH26
- CBX2
- CBX4
- CBX6
- CBX8
- CDK4
- CDK6
- CDKN2
- CDKN2A
- CDKN2B
- CDKN2C
- CDKN2D
- CDKN6
- CHET9
- CSBP
- CSBP1
- CSBP2
- CSPB1
- DING
- DP1
- DP2
- E2F1
- E2F2
- E2F3
- EDR1
- EDR2
- EDR3
- EED
- EIF2C1
- EIF2C3
- EIF2C4
- ERK1
- ERK2
- EZH2
- FOS
- G0S7
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HGK
- HIPI3
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- IFB
- IFNB
- IFNB1
- JJAZ1
- JMJD3
- JNK1
- JNK2
- JNK3
- JNK3A
- JNKK1
- JNKK2
- JUN
- KDM6B
- KIAA0075
- KIAA0160
- KIAA0346
- KIAA0551
- KIAA0687
- KIAA1093
- KIAA1460
- KIAA1567
- KIAA1582
- KIAA1631
- KMT6
- MAP2K3
- MAP2K4
- MAP2K6
- MAP2K7
- MAP3K5
- MAP4K4
- MAP4K6
- MAPK1
- MAPK10
- MAPK11
- MAPK14
- MAPK3
- MAPK8
- MAPK9
- MAPKAPK2
- MAPKAPK3
- MAPKAPK5
- MAPKKK5
- MDM2
- MDM4
- MDMX
- MEK3
- MEK4
- MEK6
- MEK7
- MEKK5
- MINK
- MINK1
- MKK3
- MKK4
- MKK6
- MKK7
- MLM
- MOV10
- MTS1
- MTS2
- MXI2
- NIK
- P53
- PC3
- PCGF4
- PH1
- PH2
- PH3
- PHC1
- PHC2
- PHC3
- PRAK
- PRKM1
- PRKM10
- PRKM11
- PRKM2
- PRKM3
- PRKM8
- PRKM9
- PRKMK3
- PRKMK4
- PRKMK6
- PRKMK7
- RBAP46
- RBAP48
- RBBP3
- RBBP4
- RBBP7
- RC1
- RING1
- RING1A
- RING1B
- RNF1
- RNF2
- RNF51
- RPS27A
- SAPK1
- SAPK1A
- SAPK1B
- SAPK1C
- SAPK2
- SAPK2A
- SAPK2B
- SEK1
- SERK1
- SKK1
- SKK2
- SKK3
- SKK4
- SUZ12
- TFDP1
- TFDP2
- TNIK
- TNRC6
- TNRC6A
- TNRC6B
- TNRC6C
- TP53
- TRDX
- TRX
- TRX1
- TSH2B
- TXN
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- YSK2
- ZC3
|
Homo sapiens (human)
|
|
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
|
|
|
|
Homo sapiens (human)
|
|
Phosphorylation of Emi1
|
|
|
- CCNB
- CCNB1
- CDC2
- CDC20
- CDC28A
- CDH1
- CDK1
- CDKN1
- EMI1
- FBX5
- FBXO5
- FYR
- FZR
- FZR1
- KIAA1242
- P34CDC2
- PLK
- PLK1
|
Homo sapiens (human)
|
|
Transcription of E2F targets under negative control by DREAM complex
|
|
|
- BARA
- BHLHD4
- BHLHE39
- C14orf46
- CDC18L
- CDC25A
- CDC6
- CXCDC1
- DP1
- DP2
- E2F1
- E2F4
- E2F5
- HDAC1
- KIAA2037
- LIN37
- LIN52
- LIN54
- LIN9
- MAX
- MYC
- PCNA
- RB2
- RBAP48
- RBBP3
- RBBP4
- RBL1
- RBL2
- RPD3L1
- TFDP1
- TFDP2
- TGS
- TOP2
- TOP2A
|
Homo sapiens (human)
|
|
CDC6 association with the ORC:origin complex
|
|
|
- C20orf154
- CDC18L
- CDC6
- LATHEO
- MCM8
- ORC1
- ORC1L
- ORC2
- ORC2L
- ORC3
- ORC3L
- ORC4
- ORC4L
- ORC5
- ORC5L
- ORC6
- ORC6L
- PARC1
|
Homo sapiens (human)
|
|
Unwinding of DNA
|
|
|
- BM28
- C20orf154
- CCNL1
- CDC21
- CDC45
- CDC45L
- CDC45L2
- CDC46
- CDC47
- CDCL1
- GINS1
- GINS2
- GINS3
- GINS4
- KIAA0030
- KIAA0186
- MCM2
- MCM3
- MCM4
- MCM5
- MCM6
- MCM7
- MCM8
- PSF1
- PSF2
- PSF3
- SLD5
|
Homo sapiens (human)
|
|
G1/S-Specific Transcription
|
|
|
- BARA
- C14orf46
- CCNA1
- CCNE
- CCNE1
- CDC18L
- CDC2
- CDC28A
- CDC45
- CDC45L
- CDC45L2
- CDC6
- CDK1
- CDKN1
- CDT1
- CXCDC1
- DHFR
- DP1
- DP2
- E2F1
- E2F4
- E2F5
- E2F6
- EMI1
- FBX5
- FBXO5
- HDAC1
- KIAA2037
- LIN37
- LIN52
- LIN54
- LIN9
- ORC1
- ORC1L
- P34CDC2
- PARC1
- PCNA
- POLA
- POLA1
- RB2
- RBAP48
- RBBP3
- RBBP4
- RBL1
- RBL2
- RPD3L1
- RR2
- RRM2
- TFDP1
- TFDP2
- TGS
- TK1
- TS
- TYMS
|
Homo sapiens (human)
|
|
Activation of the pre-replicative complex
|
|
|
- ASK
- BM28
- C20orf154
- CCNL1
- CDC18L
- CDC21
- CDC45
- CDC45L
- CDC45L2
- CDC46
- CDC47
- CDC6
- CDC7
- CDC7L1
- CDCL1
- CDK2
- CDKN2
- CDT1
- CHRAC17
- DBF4
- DBF4A
- DPE2
- GMNN
- KIAA0030
- LATHEO
- MCM10
- MCM2
- MCM3
- MCM4
- MCM5
- MCM6
- MCM7
- MCM8
- ORC1
- ORC1L
- ORC2
- ORC2L
- ORC3
- ORC3L
- ORC4
- ORC4L
- ORC5
- ORC5L
- ORC6
- ORC6L
- PARC1
- POLA
- POLA1
- POLA2
- POLE
- POLE1
- POLE2
- POLE3
- POLE4
- PRIM1
- PRIM2
- PRIM2A
- REPA1
- REPA2
- REPA3
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA4
- RPA70
- ZDBF1
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Homo sapiens (human)
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Inactivation of CDC42 and RAC1
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|
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- ARHGAP13
- ARHGAP14
- ARHGAP34
- ARHGAP39
- CDC42
- DUTT1
- FNBP2
- KIAA0411
- KIAA0456
- KIAA1156
- KIAA1304
- KIAA1688
- MEGAP
- RAC1
- ROBO1
- SLIL3
- SLIT2
- SRGAP1
- SRGAP2
- SRGAP2A
- SRGAP3
- TC25
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Homo sapiens (human)
|
|
CD28 dependent Vav1 pathway
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|
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- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- CDC42
- FYN
- LAB7
- LCK
- OPHN3
- PAK1
- PAK2
- PAK3
- RAC1
- TC25
- VAV
- VAV1
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Homo sapiens (human)
|
|
RHO GTPases activate KTN1
|
|
|
- ARH12
- ARHA
- ARHG
- CDC42
- CG1
- KIAA0004
- KIF5A
- KIF5B
- KLC
- KLC1
- KLC2
- KLC2L
- KLC3
- KLC4
- KNS
- KNS1
- KNS2
- KNSL8
- KTN1
- NKHC1
- RAC1
- RHO12
- RHOA
- RHOG
- TC25
|
Homo sapiens (human)
|
|
G beta:gamma signalling through CDC42
|
|
|
- ARHGEF6
- CDC42
- COOL2
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNG9
- GNGT1
- GNGT10
- GNGT11
- GNGT2
- GNGT3
- GNGT4
- GNGT5
- GNGT7
- GNGT8
- GNGT9
- KIAA0006
- PAK1
- PIXA
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Homo sapiens (human)
|
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