GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **901 - 925** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin-6 receptor subunit alpha Interleukin-6 Mitogen-activated protein kinase 3 Non-receptor tyrosine-protein kinase TYK2 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O60674 P05231 P06493 P08887 P23458 P27361 P29597 Q02750 Q06124	CDC2 CDC28A CDK1 CDKN1 ERK1 IFNB2 IL6 IL6R JAK1 JAK1A JAK1B JAK2 MAP2K1 MAPK3 MEK1 P34CDC2 PRKM3 PRKMK1 PTP2C PTPN11 SHPTP2 TYK2	Homo sapiens (human)
Insulin receptor signalling cascade	GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Insulin receptor Insulin SHC-transforming protein 1 Son of sevenless homolog 1	P01111 P01112 P01308 P06213 P29353 Q07889 Q13322	GRB10 GRBIR HRAS HRAS1 INS INSR KIAA0207 NRAS SHC SHC1 SHCA SOS1	Homo sapiens (human)
ATF6 (ATF6-alpha) activates chaperone genes	Calreticulin Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-dependent transcription factor ATF-6 alpha DNA damage-inducible transcript 3 protein Endoplasmic reticulum chaperone BiP Endoplasmin Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma	P11021 P14625 P18848 P18850 P23511 P25208 P27797 P35638 Q13952	ATF4 ATF6 CALR CHOP CHOP10 CREB2 CRTC DDIT3 GADD153 GRP78 GRP94 HAP3 HSP90B1 HSPA5 HSPC4 NFYA NFYB NFYC TRA1 TXREB	Homo sapiens (human)
GSD Ia	Glucose-6-phosphatase catalytic subunit 1	P35575	G6PC G6PC1 G6PT	Homo sapiens (human)
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Histone RNA hairpin-binding protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' U7 snRNA-associated Sm-like protein LSm10 U7 snRNA-associated Sm-like protein LSm11 Zinc finger protein 473	P14678 P52298 P62304 P62306 P62308 P62318 P83369 Q09161 Q14493 Q8WTR7 Q969L4	CBP20 CBP80 COD HBP KIAA1141 LSM10 LSM11 NCBP NCBP1 NCBP2 PBSCF PBSCG SLBP SNRPB SNRPB1 SNRPD3 SNRPE SNRPF SNRPG ZFP100 ZNF473	Homo sapiens (human)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 C-type lectin domain family 7 member A Caspase recruitment domain-containing protein 11 Caspase recruitment domain-containing protein 9 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95999 P0CG47 P0CG48 P16885 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43405 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 Q04206 Q05655 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N5C8 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9BXN2 Q9H257 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BGR BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARD9 CARMA1 CDC34 CHUK CIPER CLAP CLEC7A CLECSF12 CROC1 CUL1 DECTIN1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PKCD PLCG2 POH1 PRKCD PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 SYK TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z	Homo sapiens (human)
Defective factor XII causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Prothrombin	P00734 P00748 P03952	F12 F2 KLK3 KLKB1	Homo sapiens (human)
Degradation of GLI1 by the proteasome	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein numb homolog S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P08151 P0CG47 P0CG48 P17612 P17980 P20618 P22612 P22694 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49757 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96J02 Q99436 Q99460 Q9UL46 Q9UMX1 Q9UNM6 Q9Y297	BTRC BTRCP C14orf41 C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GLI GLI1 HC2 HC3 HC8 HC9 HSPC IFI5111 ITCH KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU NUMB OCP2 PFAAP4 PKACA POH1 PRKACA PRKACB PRKACG PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUFU SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of other transcription factors	Cbp/p300-interacting transactivator 2 Pituitary homeobox 2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P05549 Q92754 Q99697 Q99967	AP2TF ARP1 CITED2 MRG1 PITX2 RGS RIEG RIEG1 TFAP2 TFAP2A TFAP2C	Homo sapiens (human)
HHAT G278V doesn't palmitoylate Hh-Np	Desert hedgehog protein Indian hedgehog protein Protein-cysteine N-palmitoyltransferase HHAT Sonic hedgehog protein	O43323 Q14623 Q15465 Q5VTY9	DHH HHAT IHH MART2 SHH SKI1	Homo sapiens (human)
Selenoamino acid metabolism	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase Eukaryotic translation elongation factor 1 epsilon-1 Glutamine--tRNA ligase Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lysine--tRNA ligase Methionine--tRNA ligase, cytoplasmic	O43324 P07814 P14868 P41252 P47897 P54136 P56192 Q12904 Q13155 Q15046 Q9P2J5	AIMP1 AIMP2 AIMP3 DARS DARS1 EEF1E1 EMAP2 EPRS EPRS1 GLNS IARS IARS1 JTV1 KARS KARS1 KIAA0070 KIAA1352 LARS LARS1 MARS MARS1 P18 PARS QARS QARS1 QPRS RARS RARS1 SCYE1	Homo sapiens (human)
Nef Mediated CD8 Down-regulation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD8 beta chain V-type proton ATPase subunit H	O94973 O95782 P04601 P10966 P53680 P63010 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ATP6V1H CD8B CD8B1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 nef	Homo sapiens (human)
Reuptake of GABA	Sodium- and chloride-dependent GABA transporter 1 Sodium- and chloride-dependent GABA transporter 2 Sodium- and chloride-dependent GABA transporter 3 Sodium- and chloride-dependent betaine transporter	P30531 P48065 P48066 Q9NSD5	BGT1 GABATR GABT1 GABT3 GAT1 GAT2 GAT3 SLC6A1 SLC6A11 SLC6A12 SLC6A13	Homo sapiens (human)
gilteritinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
Ribosomal scanning and start codon recognition	Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 1A, X-chromosomal Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Eukaryotic translation initiation factor 4H Eukaryotic translation initiation factor 5 Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00303 O15371 O15372 O75821 O75822 P05198 P06730 P08708 P08865 P15880 P20042 P22090 P23396 P23588 P25398 P39019 P41091 P42677 P46781 P46782 P46783 P47813 P55010 P55884 P60228 P60842 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 Q04637 Q13347 Q14152 Q14240 Q15056 Q71UM5 Q7L2H7 Q8TD47 Q99613 Q9UBQ5 Q9Y262	CCG2 D6S218E DDX2A DDX2B EIF1A EIF1AX EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3EIP EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF3S1 EIF3S10 EIF3S12 EIF3S2 EIF3S3 EIF3S4 EIF3S5 EIF3S6 EIF3S6IP EIF3S7 EIF3S8 EIF3S9 EIF4A EIF4A1 EIF4A2 EIF4B EIF4C EIF4E EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI EIF4H EIF5 FAU FTE1 HFLB5 INT6 KIAA0038 KIAA0139 LAMBR LAMR1 MFTL MPS1 PCID1 RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR TRIP1 UBA80 UBCEP1 WBSCR1 WSCR1	Homo sapiens (human)
CDK-mediated phosphorylation and removal of Cdc6	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division control protein 6 homolog Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Fizzy-related protein homolog G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O00762 O14818 O43242 O75832 O96020 P0CG47 P0CG48 P17980 P20248 P20618 P24864 P24941 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P78396 Q06323 Q13042 Q13200 Q14997 Q15008 Q16401 Q16763 Q8NHZ8 Q8TAA3 Q92530 Q96DE5 Q99436 Q99460 Q99741 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDC16 CDC18L CDC23 CDC26 CDC27 CDC6 CDH1 CDK2 CDKN2 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 KIAA1242 KIAA1406 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z	Homo sapiens (human)
MECP2 regulates transcription factors	Myocyte-specific enhancer factor 2C Peroxisome proliferator-activated receptor gamma RNA binding protein fox-1 homolog 1	P37231 Q06413 Q9NWB1	A2BP A2BP1 FOX1 HRNBP1 MEF2C NR1C3 PPARG RBFOX1	Homo sapiens (human)
Suppression of autophagy	Dual specificity protein phosphatase 16 N-acetyltransferase Eis Phosphatidylinositol-3-phosphatase Ras-related protein Rab-7a	O53361 P51149 P9WFK7 Q9BY84	DUSP16 KIAA1700 MKP7 RAB7 RAB7A eis sapM	Homo sapiens (human)
Nuclear Pore Complex (NPC) Disassembly	Aladin Cyclin-dependent kinase 1 E3 SUMO-protein ligase RanBP2 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Serine/threonine-protein kinase Nek6 Serine/threonine-protein kinase Nek7 Serine/threonine-protein kinase Nek9 mRNA export factor RAE1	A8CG34 O15504 O75694 O95067 P06493 P12270 P14635 P35658 P37198 P49790 P49792 P55735 P57740 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TD19 Q8TDX7 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9HC98 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 CG1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KIAA1995 MP44 MRNP41 NDC1 NEK6 NEK7 NEK8 NEK9 NERCC NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 P34CDC2 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
Constitutive Signaling by AKT1 E17K in Cancer	3-phosphoinositide-dependent protein kinase 1 Bcl2-associated agonist of cell death Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Inhibitor of nuclear factor kappa-B kinase subunit alpha Nuclear receptor subfamily 4immunitygroup A member 1 Proline-rich AKT1 substrate 1 Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ribosomal protein S6 kinase beta-2 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tuberin	A8MYZ6 O15111 O15530 O43524 P22736 P31749 P31751 P38936 P42345 P46527 P49815 P49840 P49841 P55211 P85299 P98177 Q00987 Q12778 Q6R327 Q92934 Q96B36 Q9BPZ7 Q9BVC4 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT1S1 AKT2 AKT3 BAD BBC6 BCL2L8 CAP20 CASP9 CDKN1 CDKN1A CDKN1B CHUK CIP1 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 FRAP FRAP1 FRAP2 GBL GFRP1 GSK3A GSK3B HMR IKKA KIAA1999 KIP1 LST8 MAPKAP1 MCH6 MDA6 MDM2 MIP1 MLLT7 MLST8 MTOR NAK1 NR4A1 PDK1 PDPK1 PIC1 PKB PKBG PRAS40 PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR RPS6KB2 SDI1 SIN1 STK14B TCF16 TSC2 TSC4 WAF1 p27	Homo sapiens (human)
Cross-presentation of particulate exogenous antigens (phagosomes)	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Integrin alpha-V Integrin beta-5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Platelet glycoprotein 4	P04839 P06756 P13498 P14598 P16671 P18084 P19878 Q15080	CD36 CYBA CYBB GP3B GP4 ITGAV ITGB5 MSK8 NCF1 NCF2 NCF4 NOX2 NOXA2 NOXO2 P67PHOX SH3PXD1A SH3PXD4 VNRA VTNR	Homo sapiens (human)
Synthesis of pyrophosphates in the cytosol	Diphosphoinositol polyphosphate phosphohydrolase 1 Diphosphoinositol polyphosphate phosphohydrolase 2 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha Diphosphoinositol polyphosphate phosphohydrolase 3-beta Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 Inositol hexakisphosphate kinase 1 Inositol hexakisphosphate kinase 3 Inositol-pentakisphosphate 2-kinase Inositol-tetrakisphosphate 1-kinase	O43314 O95989 Q13572 Q6PFW1 Q8NFP7 Q92551 Q96G61 Q96PC2 Q9H8X2 Q9NZJ9	APS1 APS2 C9orf12 DIPP DIPP1 DIPP2 DIPP3A DIPP3B HISPPD1 HISPPD2A IHPK1 IHPK3 IP6K IP6K1 IP6K3 IPPK IPS1 ITPK1 KIAA0263 KIAA0377 KIAA0433 KIAA0487 NUDT10 NUDT11 NUDT3 NUDT4 PPIP5K1 PPIP5K2 VIP1 VIP2	Homo sapiens (human)
Regulation of NFE2L2 gene expression	CREB-binding protein Histone acetyltransferase p300 Myc proto-oncogene protein Neurogenic locus notch homolog protein 1 Nuclear factor NF-kappa-B p105 subunit Nuclear factor erythroid 2-related factor 2 Transcription factor MafK Transcription factor p65	O60675 P01106 P19838 P46531 Q04206 Q09472 Q16236 Q92793	BHLHE39 CBP CREBBP EP300 MAFK MYC NFE2L2 NFKB1 NFKB3 NOTCH1 NRF2 P300 RELA TAN1	Homo sapiens (human)
STING mediated induction of host immune responses	Cyclic GMP-AMP synthase E3 ubiquitin-protein ligase TRIM21 Gamma-interferon-inducible protein 16 Probable ATP-dependent RNA helicase DDX41 Stimulator of interferon genes protein	P19474 Q16666 Q86WV6 Q8N884 Q9UJV9	ABS C6orf150 CGAS DDX41 ERIS IFI16 IFNGIP1 MB21D1 MITA RNF81 RO52 SSA1 STING STING1 TMEM173 TRIM21	Homo sapiens (human)
Conjugation of benzoate with glycine	Acyl-coenzyme A synthetase ACSM1, mitochondrial Acyl-coenzyme A synthetase ACSM2B, mitochondrial Glycine N-acyltransferase-like protein 1 Glycine N-acyltransferase-like protein 2 Glycine N-acyltransferase-like protein 3 Glycine N-acyltransferase	Q08AH1 Q5SZD4 Q68CK6 Q6IB77 Q8WU03 Q969I3	ACGNAT ACSM1 ACSM2 ACSM2B BUCS1 C6orf140 CAT GAT GLYAT GLYATL1 GLYATL2 GLYATL3 GNAT LAE MACS1	Homo sapiens (human)

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