GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **901 - 925** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism
Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)	Organic cation/carnitine transporter 2	O76082	OCTN2 SLC22A5	Homo sapiens (human)
Cholesterol biosynthesis	3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 Acetyl-CoA acetyltransferase, cytosolic Delta(14)-sterol reductase LBR Delta(14)-sterol reductase TM7SF2 Delta(24)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Isopentenyl-diphosphate delta-isomerase 2 Lanosterol 14-alpha demethylase Lanosterol synthase Methylsterol monooxygenase 1 Mevalonate kinase Phosphomevalonate kinase Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 Protein ARV1 Squalene monooxygenase Squalene synthase Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	O76062 O95749 P14324 P36956 P37268 P48449 P53602 P56937 Q01581 Q03426 Q12772 Q13907 Q14534 Q14739 Q15126 Q15392 Q15738 Q15800 Q16850 Q8IY26 Q9BWD1 Q9BXS1 Q9H2C2	17HSD7 ACAT2 ACTL ANG1 ARV1 BHLHD1 BHLHD2 CYP51 CYP51A1 DESP4 DHCR24 ERG1 ERG25 FDFT1 FDPS FPS GGPS1 H105E3 HMGCS HMGCS1 HSD17B7 IDI1 IDI2 KIAA0018 KIAA1293 LBR LSS MPD MSMO1 MVD MVK NSDHL OSC PDP1 PLPP6 PMKI PMVK PPAPDC2 SC4MOL SDR37C1 SQLE SREBF1 SREBF2 SREBP1 SREBP2 TM7SF2	Homo sapiens (human)
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceruloplasmin Cullin-1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 Ferritin heavy chain Ferritin light chain Ferritin, mitochondrial Glutaredoxin-3 Heme oxygenase 1 Heme oxygenase 2 Hephaestin Iron-responsive element-binding protein 2 NEDD8 Natural resistance-associated macrophage protein 2 Neutrophil gelatinase-associated lipocalin Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Polyubiquitin-C Proton-coupled folate transporter S-phase kinase-associated protein 1 Serotransferrin Solute carrier family 22 member 17 Solute carrier family 40 member 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O76003 P00450 P02787 P02792 P02794 P09601 P0CG47 P0CG48 P21399 P30519 P48200 P49281 P62979 P62987 P63208 P80188 Q13616 Q15843 Q53TN4 Q86VP6 Q8N4E7 Q8WUG5 Q96NT5 Q9BQS7 Q9NP59 Q9UKA1 Q9UNQ0	ABCG2 ABCP ACO1 BCRP BCRP1 BOCT BOIT CAND1 CP CUL1 CYBRD1 DCT1 DCYTB DMT1 EMC19 FBL4 FBL5 FBXL5 FLR1 FPN FPN1 FRRS3 FTH FTH1 FTHL6 FTL FTMT G21 GLRX3 HCP1 HEPH HMOX1 HMOX2 HNL HO HO1 HO2 IREB1 IREB2 IREG1 KIAA0698 KIAA0829 LCN2 MXR NEDD8 NGAL NRAMP2 OCP2 PCFT PICOT RPS27A SKP1 SKP1A SLC11A2 SLC11A3 SLC22A17 SLC40A1 SLC46A1 TCEB1L TF TIP120 TIP120A TXNL2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Formation of ATP by chemiosmotic coupling	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial	O75947 O75964 P00846 P03928 P05496 P06576 P18859 P24539 P25705 P30049 P36542 P48047 P48201 P56134 P56381 P56385 Q06055 Q99766	ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5D ATP5E ATP5F1 ATP5F1A ATP5F1B ATP5F1C ATP5F1D ATP5F1E ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5JL ATP5K ATP5L ATP5MC1 ATP5MC2 ATP5MC3 ATP5ME ATP5MF ATP5MG ATP5O ATP5PB ATP5PD ATP5PF ATP5PO ATP5S ATP6 ATP8 ATPASE6 ATPASE8 ATPM ATPMB ATPO ATPSB ATPW DMAC2L MT-ATP6 MT-ATP8 MTATP6 MTATP8	Homo sapiens (human)
Carnitine synthesis	4-trimethylaminobutyraldehyde dehydrogenase Gamma-butyrobetaine dioxygenase Serine hydroxymethyltransferase, cytosolic Trimethyllysine dioxygenase, mitochondrial	O75936 P34896 P49189 Q9NVH6	ALDH4 ALDH7 ALDH9 ALDH9A1 BBH BBOX BBOX1 SHMT1 TMLH TMLHE	Homo sapiens (human)
Formation of Incision Complex in GG-NER	CDK-activating kinase assembly factor MAT1 Centrin-2 Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA repair endonuclease XPF DNA repair protein complementing XP-A cells DNA repair protein complementing XP-C cells E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 ubiquitin-protein ligase Arkadia E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 UV excision repair protein RAD23 homolog A UV excision repair protein RAD23 homolog B Ubiquitin carboxyl-terminal hydrolase 45 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O75925 P07992 P09874 P0CG47 P0CG48 P15927 P18074 P19447 P23025 P27694 P28715 P32780 P35244 P41208 P50613 P51946 P51948 P54725 P54727 P55854 P61088 P61956 P62877 P62979 P62987 P63165 P63279 Q01831 Q13619 Q13620 Q13888 Q13889 Q15819 Q16531 Q6ZNA4 Q6ZYL4 Q70EL2 Q86WJ1 Q92466 Q92759 Q92889 Q9UGN5 Q9Y6X2	ADPRT ADPRT2 ADPRTL2 ALC1 BLU BTF2 BTF2P44 C6orf175 CAK CAK1 CALT CAP35 CCNH CDK7 CDKN7 CEN2 CETN2 CHD1L CUL4A CUL4B DDB1 DDB2 DDXBP1 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0695 MAT1 MMS2 MNAT1 MO15 PARP1 PARP2 PIAS1 PIAS3 PPOL RAD23A RAD23B RBX1 REPA1 REPA2 REPA3 RNF111 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 STK1 SUMO1 SUMO2 SUMO3 TTDA UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UBL1 UEV2 USP45 XAP1 XPA XPAC XPB XPBC XPC XPCC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
SUMOylation of intracellular receptors	Androgen receptor E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 Estrogen receptor Glucocorticoid receptor Histone deacetylase 4 Mineralocorticoid receptor Nuclear receptor ROR-alpha Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 4 group A member 2 Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma Progesterone receptor Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Steroidogenic factor 1 Thyroid hormone receptor beta Vitamin D3 receptor	O75925 P03372 P04150 P06401 P08235 P10275 P10276 P10828 P11473 P13056 P19793 P35398 P37231 P43354 P55055 P55854 P56524 P61956 P63165 P63279 Q07869 Q13285 Q8N2W9 Q9Y6X2	AD4BP AR DDXBP1 DHTR ERBA2 ESR ESR1 FTZF1 GRL HDAC4 KIAA0288 LXRB MCR MLR NER NOT NR1A2 NR1B1 NR1C1 NR1C3 NR1F1 NR1H2 NR1I1 NR2B1 NR2C1 NR3A1 NR3C1 NR3C2 NR3C3 NR3C4 NR4A2 NR5A1 NURR1 PGR PIAS1 PIAS3 PIAS4 PIASG PPAR PPARA PPARG RARA RORA RXRA RZRA SF1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 THR1 THRB TINUR TR2 UBC9 UBCE9 UBE2I UBL1 UNR VDR	Homo sapiens (human)
CD28 dependent Vav1 pathway	Cell division control protein 42 homolog Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O75914 P06239 P06241 P10747 P15498 P33681 P42081 P60953 P63000 Q13153 Q13177	CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 CDC42 FYN LAB7 LCK OPHN3 PAK1 PAK2 PAK3 RAC1 TC25 VAV VAV1	Homo sapiens (human)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase delta Diacylglycerol kinase epsilon Diacylglycerol kinase eta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase kappa Diacylglycerol kinase theta Diacylglycerol kinase zeta Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O75912 O95267 P23743 P24723 P49619 P52429 P52824 Q02156 Q04759 Q05655 Q13507 Q13574 Q14571 Q14573 Q14643 Q16760 Q5KSL6 Q7LDG7 Q86XP1 Q9HCX4 Q9Y210 Q9Y6T7	CDC25L DAGK DAGK1 DAGK2 DAGK3 DAGK4 DAGK5 DAGK6 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKK DGKQ DGKZ INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0145 KIAA0718 MCG7 PKCD PKCE PKCL PRKCD PRKCE PRKCH PRKCL PRKCQ PRKCT RASGRP RASGRP1 RASGRP2 TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
The retinoid cycle in cones (daylight vision)	Acyl-CoA wax alcohol acyltransferase 2 Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Retinaldehyde-binding protein 1 Retinol-binding protein 3 Short-chain dehydrogenase/reductase 3 Short-wave-sensitive opsin 1	O75911 P03999 P04000 P04001 P10745 P12271 Q6E213	AWAT2 BCP CRALBP DC4 DGAT2L4 DHRS3 GCP MFAT OPN1LW OPN1MW OPN1SW RBP3 RCP RDH17 RLBP1 SDR16C1 WS	Homo sapiens (human)
Acyl chain remodeling of DAG and TAG	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 Acyl-CoA wax alcohol acyltransferase 2 Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2-like protein 6 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain-containing protein 2	O75907 Q6E213 Q6ZPD8 Q96AD5 Q96PD7 Q99685 Q9NST1	ADPN AGRP1 ATGL AWAT2 C22orf20 DC3 DC4 DGAT DGAT1 DGAT2 DGAT2L4 DGAT2L6 MFAT MGLL PNPLA2 PNPLA3 WS	Homo sapiens (human)
Triglyceride biosynthesis	2-acylglycerol O-acyltransferase 1 2-acylglycerol O-acyltransferase 2 2-acylglycerol O-acyltransferase 3 Alkylglycerol monooxygenase Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2 Glycerol kinase 2 Glycerol kinase 3 Glycerol kinase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Phosphatidate phosphatase LPIN1 Phosphatidate phosphatase LPIN2 Phosphatidate phosphatase LPIN3	O75907 P32189 Q14409 Q14410 Q14693 Q3SYC2 Q6NUI2 Q6ZNB7 Q86VF5 Q92539 Q96PD6 Q96PD7 Q9BQK8 Q9HCL2	AGMO AGRP1 DC2 DC5 DC7 DGAT DGAT1 DGAT2 DGAT2L1 DGAT2L5 DGAT2L7 GK GK2 GK3 GK3P GKP2 GKP3 GKTA GKTB GPAM GPAT1 GPAT2 KIAA0188 KIAA0249 KIAA1560 LIPN3L LPIN1 LPIN2 LPIN3 MOGAT1 MOGAT2 MOGAT3 TMEM195	Homo sapiens (human)
GABA B receptor activation	Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2	O75899 Q9UBS5	GABBR1 GABBR2 GPR51 GPRC3A GPRC3B	Homo sapiens (human)
Metabolism of folate and pterines	5-formyltetrahydrofolate cyclo-ligase Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial C-1-tetrahydrofolate synthase, cytoplasmic Cytosolic 10-formyltetrahydrofolate dehydrogenase Dihydrofolate reductase 2, mitochondrial Dihydrofolate reductase Folate receptor beta Methylenetetrahydrofolate reductase (NADPH) Mitochondrial 10-formyltetrahydrofolate dehydrogenase Monofunctional C1-tetrahydrofolate synthase, mitochondrial Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase, cytosolic Serine hydroxymethyltransferase, mitochondrial Solute carrier family 25 member 32	O75891 P00374 P11586 P13995 P14207 P34896 P34897 P41440 P42898 P49914 Q3SY69 Q6UB35 Q86XF0 Q96NT5 Q9H2D1 Q9H903	ALDH1L1 ALDH1L2 DHFR DHFR2 DHFRL1 DHFRP4 FLOT1 FOLR2 FTHFD FTHFSDC1 G21 HCP1 MFT MFTC MTHFC MTHFD MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS NMDMC PCFT RFC1 SHMT1 SHMT2 SLC19A1 SLC25A32 SLC46A1	Homo sapiens (human)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Bile acid receptor Cytochrome P450 7A1 Cytochrome P450 7B1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	O75881 P17516 P19793 P22680 P42330 P51857 P52895 Q02318 Q04828 Q15596 Q15788 Q16647 Q96RI1 Q9H2F3 Q9UNU6	AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 BAR BHLHE74 BHLHE75 CHDR CYP12 CYP27 CYP27A1 CYP7 CYP7A1 CYP7B1 CYP8 CYP8A1 CYP8B1 DDH DDH1 DDH2 FXR HRR1 HSD17B5 HSD3B7 KIAA0119 NCOA1 NCOA2 NR1H4 NR2B1 PGFS PTGIS RIP14 RXRA SRC1 SRC2 SRD5B1 TIF2	Homo sapiens (human)
Synthesis of bile acids and bile salts	Bile acid receptor Cholesterol 25-hydroxylase Cytochrome P450 7A1 Cytochrome P450 7B1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Oxysterol-binding protein 1 Oxysterol-binding protein-related protein 1 Oxysterol-binding protein-related protein 2 Oxysterol-binding protein-related protein 3 Oxysterol-binding protein-related protein 6 Oxysterol-binding protein-related protein 7 Oxysterol-binding protein-related protein 9 Retinoic acid receptor RXR-alpha	O75881 O95992 P19793 P22059 P22680 Q15596 Q15788 Q96RI1 Q96SU4 Q9BXW6 Q9BZF2 Q9BZF3 Q9H1P3 Q9H4L5	BAR BHLHE74 BHLHE75 CH25H CYP7 CYP7A1 CYP7B1 FXR HRR1 KIAA0704 KIAA0772 NCOA1 NCOA2 NR1H4 NR2B1 ORP1 ORP2 ORP3 ORP6 ORP7 ORP9 OSBP OSBP1 OSBP3 OSBP4 OSBP8 OSBPL1 OSBPL1A OSBPL1B OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RIP14 RXRA SRC1 SRC2 TIF2	Homo sapiens (human)
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate	Isocitrate dehydrogenase [NADP] cytoplasmic	O75874	IDH1 PICD	Homo sapiens (human)
NFE2L2 regulating TCA cycle genes	Isocitrate dehydrogenase [NADP] cytoplasmic NADP-dependent malic enzyme Nuclear factor erythroid 2-related factor 2	O75874 P48163 Q16236	IDH1 ME1 NFE2L2 NRF2 PICD	Homo sapiens (human)
NADPH regeneration	Cytoplasmic aconitate hydratase Isocitrate dehydrogenase [NADP] cytoplasmic	O75874 P21399	ACO1 IDH1 IREB1 PICD	Homo sapiens (human)
Kandutsch-Russell pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Bloch pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Response of EIF2AK1 (HRI) to heme deficiency	Asparagine synthetase [glutamine-hydrolyzing] CCAAT/enhancer-binding protein beta CCAAT/enhancer-binding protein gamma Cyclic AMP-dependent transcription factor ATF-3 Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-dependent transcription factor ATF-5 DNA damage-inducible transcript 3 protein Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 2-alpha kinase 1 Glutathione-specific gamma-glutamylcyclotransferase 1 Growth factor receptor-bound protein 10 Protein phosphatase 1 regulatory subunit 15A Tribbles homolog 3	O75807 P05198 P08243 P17676 P18847 P18848 P20042 P35638 P41091 P53567 Q13322 Q96RU7 Q9BQI3 Q9BUX1 Q9Y2D1	ASNS ATF3 ATF4 ATF5 ATFX BOTCH C20orf97 CEBPB CEBPG CHAC1 CHOP CHOP10 CREB2 DDIT3 EIF2A EIF2AK1 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 GADD153 GADD34 GRB10 GRBIR HRI KIAA0207 KIAA1369 NIPK PPP1R15A SKIP3 TCF5 TRB3 TRIB3 TS11 TXREB	Homo sapiens (human)
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 ATP-dependent translocase ABCB1 Albumin Aldo-keto reductase family 1 member C1 Corticosteroid-binding globulin Cytochrome P450 3A4 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B7	O75795 P02768 P08183 P08185 P08684 P16662 P28845 P35503 P80365 Q04828	ABCB1 AKR1C1 ALB CBG CYP3A3 CYP3A4 DDH DDH1 GNT1 HSD11 HSD11B1 HSD11B2 HSD11K HSD11L MDR1 PGY1 SDR26C1 SDR9C3 SERPINA6 UGT1 UGT1A3 UGT2B17 UGT2B7 UGTB2B9	Homo sapiens (human)
CD28 co-stimulation	GRB2-related adapter protein 2 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O75791 P06239 P06241 P07947 P07948 P10747 P33681 P42081	CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 FYN GADS GRAP2 GRB2L GRID JTK8 LAB7 LCK LYN YES YES1	Homo sapiens (human)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase N Angiotensin-converting enzyme 2 Angiotensin-converting enzyme Angiotensinogen Carboxypeptidase B2 Carboxypeptidase B Cathepsin D Cathepsin G Cathepsin Z Chymase Glutamyl aminopeptidase Granzyme H Liver carboxylesterase 1 Mast cell carboxypeptidase A Neprilysin Renin receptor Renin	O75787 P00797 P01019 P07339 P08311 P08473 P12821 P15086 P15088 P15144 P20718 P23141 P23946 Q07075 Q96IY4 Q9BYF1 Q9UBR2	ACE ACE2 AGT ANPEP APN ATP6AP2 ATP6IP2 CAPER CD13 CES1 CES2 CGL2 CMA1 CPA3 CPB CPB1 CPB2 CPSD CTSD CTSG CTSGL2 CTSZ CYH CYM DCP DCP1 ELDF10 ENPEP EPN GZMH MME PCPB PEPN REN SERPINA8 SES1	Homo sapiens (human)

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