GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1401 - 1425** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 ZW10 interactor	O00139 O14576 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60566 O75122 O95229 P30153 P30154 P30622 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P62714 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14738 Q15172 Q15173 Q15691 Q16537 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q8N0S6 Q8N2Z9 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8WUM0 Q8WVK7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96EA4 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NXR1 Q9P258 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 ARK2 AURKB B9D2 BIRC5 BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 CASC5 CCDC99 CDC20 CDCA1 CDCA8 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CYLN1 D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EOPA ERCC6L FAAP16 FAM33A FSHPRH1 HDLC1 HEC HEC1 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0097 KIAA0166 KIAA0197 KIAA0325 KIAA0622 KIAA0627 KIAA1361 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDS MHF1 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MPS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PESCRG3 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RANBP2 RANGAP1 RCC2 RPS27 RSN SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STK1 STK12 STK5 TAOK1 TD60 TMBS62 TXBP181 XPO1 ZW10 ZWILCH ZWINT	Homo sapiens (human)
Signaling by plasma membrane FGFR1 fusions	BAG family molecular chaperone regulator 4 Erlin-2 Fibroblast growth factor receptor 1	O94905 O95429 P11362	BAG4 BFGFR C8orf2 CEK ERLIN2 FGFBR FGFR1 FLG FLT2 HBGFR SODD SPFH2	Homo sapiens (human)
Entry of Influenza Virion into Host Cell via Endocytosis	Clathrin heavy chain 1 Clathrin light chain A Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821 P09496 Q00610	CLH17 CLTA CLTC CLTCL2 HA KIAA0034 M NA NP NS PA PB1 PB2	Homo sapiens (human)
Defective MPI causes CDG-1b	Mannose-6-phosphate isomerase	P34949	MPI PMI1	Homo sapiens (human)
Atorvastatin ADME	ATP-binding cassette sub-family C member 2 ATP-dependent translocase ABCB1 Cytochrome P450 3A4 Serum paraoxonase/arylesterase 1 Serum paraoxonase/lactonase 3 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A3	P08183 P08684 P27169 P35503 Q15166 Q92887 Q9NPD5 Q9Y6L6	ABCB1 ABCC2 CMOAT CMOAT1 CMRP CYP3A3 CYP3A4 GNT1 LST1 LST2 MDR1 MRP2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC PGY1 PON PON1 PON3 SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A3	Homo sapiens (human)
Defective EXT2 causes exostoses 2	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Exostosin-1 Exostosin-2 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4	O00468 O75056 O75487 P18827 P31431 P34741 P35052 P51654 P78333 P98160 Q16394 Q8N158 Q93063 Q9Y625	AGRIN AGRN EXT1 EXT2 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 OCI5 SDC SDC1 SDC2 SDC3 SDC4	Homo sapiens (human)
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	Homeobox protein Nkx-2.2 Insulinoma-associated protein 1 Neurogenic differentiation factor 1 Neurogenin-3 Paired box protein Pax-4	O43316 O95096 Q01101 Q13562 Q9Y4Z2	ATOH5 BHLHA3 BHLHA7 IA1 INSM1 NEUROD NEUROD1 NEUROG3 NGN3 NKX2-2 NKX2.2 NKX2B PAX4	Homo sapiens (human)
Sema3A PAK dependent Axon repulsion	Cofilin-1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O75051 O75914 P06241 P07332 P07900 P08238 P23528 P51805 P53667 P63000 Q13153 Q13177 Q14563 Q9HCM2 Q9UIW2	CFL CFL1 FES FPS FYN HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0463 KIAA1550 LIMK LIMK1 NOV NRP NRP1 OCT OPHN3 PAK1 PAK2 PAK3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 SEMA3A SEMAD SEX TC25 VEGF165R	Homo sapiens (human)
Replication of the SARS-CoV-2 genome	Probable ATP-dependent RNA helicase DDX5 Replicase polyprotein 1a Replicase polyprotein 1ab Retinoblastoma-associated protein Zinc finger CCHC-type and RNA-binding motif-containing protein 1 von Hippel-Lindau disease tumor suppressor	P06400 P0DTC1 P0DTD1 P17844 P40337 Q8TBF4	DDX5 G17P1 HELR HLR1 RB1 VHL ZCRB1 rep	Homo sapiens (human)
ASP-3026-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)
CD163 mediating an anti-inflammatory response	Disintegrin and metalloproteinase domain-containing protein 17 Furin Inactive rhomboid protein 2 Interleukin-10 Interleukin-6 Mitogen-activated protein kinase 14 Myosin-9 Scavenger receptor cysteine-rich type 1 protein M130 Serine/threonine-protein kinase PLK2	P05231 P09958 P22301 P35579 P78536 Q16539 Q6PJF5 Q86VB7 Q9NYY3	ADAM17 CD163 CSBP CSBP1 CSBP2 CSPB1 CSVP FUR FURIN IFNB2 IL10 IL6 IRHOM2 M130 MAPK14 MXI2 MYH9 PACE PCSK3 PLK2 RHBDF2 RHBDL5 RHBDL6 SAPK2A SNK TACE	Homo sapiens (human)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 6 Acyl-coenzyme A thioesterase 8 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 P09110 P33897 P51659 Q08426 Q3I5F7 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT6 ACOT8 ACTEIII ALD C14orf42 DECR2 ECHD EDH17B4 EHHADH HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1	Homo sapiens (human)
Glycosphingolipid catabolism	Acid ceramidase Alpha-galactosidase A Arylsulfatase A Arylsulfatase B Arylsulfatase D Arylsulfatase F Arylsulfatase G Arylsulfatase H Arylsulfatase I Arylsulfatase J Arylsulfatase K Arylsulfatase L Beta-galactosidase-1-like protein 2 Beta-galactosidase-1-like protein 3 Beta-galactosidase-1-like protein Beta-galactosidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Cation-dependent mannose-6-phosphate receptor Cytosolic beta-glucosidase Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 Formylglycine-generating enzyme Galactocerebrosidase Ganglioside GM2 activator Inactive C-alpha-formylglycine-generating enzyme 2 Lysosomal acid glucosylceramidase Lysosomal protective protein Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sialidase-2 Sialidase-3 Sphingomyelin phosphodiesterase 2 Sphingomyelin phosphodiesterase 3 Sphingomyelin phosphodiesterase 4 Sphingomyelin phosphodiesterase Steryl-sulfatase	O60906 P04062 P06280 P06865 P07602 P07686 P08842 P10619 P15289 P15848 P16278 P17405 P17900 P20645 P51689 P51690 P54793 P54803 Q13510 Q5FYA8 Q5FYB0 Q5FYB1 Q6UWU2 Q6UWV6 Q6UWY0 Q8IW92 Q8NBJ7 Q8NBK3 Q8NCI6 Q96EG1 Q99519 Q9H227 Q9HCG7 Q9NR71 Q9NXE4 Q9NY59 Q9UQ49 Q9Y3R4	ARSA ARSB ARSC1 ARSD ARSE ARSF ARSG ARSH ARSI ARSJ ARSK ARSL ASAH ASAH1 ASAH2 ASM CBG CBGL1 CTSA ELNR1 ENPP7 GALC GBA GBA1 GBA2 GBA3 GC GLA GLB1 GLB1L GLB1L2 GLB1L3 GLBA GLUC GM2A HEXA HEXB HNAC1 KIAA1001 KIAA1418 KIAA1605 M6PR MPR46 MPRD NANH NEU1 NEU2 NEU3 PPGB PSAP SAP1 SKNY SMPD1 SMPD2 SMPD3 SMPD4 SPG46 STS SUMF1 SUMF2 TSULF	Homo sapiens (human)	G09546QO G27025MB G58161NS
Endosomal/Vacuolar pathway	Beta-2-microglobulin Cathepsin L2 Cathepsin S HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Leucyl-cystinyl aminopeptidase Procathepsin L Putative HLA class I histocompatibility antigen, alpha chain H	O60911 P01889 P01893 P04439 P07711 P10321 P13747 P17693 P25774 P30511 P61769 Q9UIQ6	B2M CATL2 CTSL CTSL1 CTSL2 CTSS CTSU CTSV HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH LNPEP OTASE	Homo sapiens (human)
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	Polyunsaturated fatty acid 5-lipoxygenase Prostaglandin G/H synthase 2	P09917 P35354	ALOX5 COX2 LOG5 PTGS2	Homo sapiens (human)
Cellular hexose transport	Fibroblast growth factor 21 Probable glucose sensor protein SLC5A4 Sodium-dependent glucose transporter 1 Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 2 Sodium/glucose cotransporter 4 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 11 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 14 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 2, facilitated glucose transporter member 6 Solute carrier family 2, facilitated glucose transporter member 7 Solute carrier family 2, facilitated glucose transporter member 8 Solute carrier family 2, facilitated glucose transporter member 9 Solute carrier family 45 member 3 Sugar transporter SWEET1	A0PJK1 O95528 P11166 P11168 P11169 P13866 P14672 P31639 Q2M3M2 Q5TF39 Q6PXP3 Q8TD20 Q8TDB8 Q96JT2 Q9BRV3 Q9BYW1 Q9NRM0 Q9NSA1 Q9NY64 Q9NY91 Q9UGQ3	FGF21 GLUT1 GLUT10 GLUT11 GLUT12 GLUT14 GLUT2 GLUT3 GLUT4 GLUT6 GLUT7 GLUT8 GLUT9 GLUTX1 KIAA1919 MFSD4B NAGLT1 NAGT PCANAP6 PRST RAG1AP1 SAAT1 SCP SGLT1 SGLT2 SGLT3 SGLT4 SGLT5 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A14 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Homo sapiens (human)	G58161NS G70323CJ
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	CREB-binding protein Cullin-1 Cyclin-C Cyclin-dependent kinase 8 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B E3 ubiquitin-protein ligase RBX1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Myc proto-oncogene protein Neurogenic locus notch homolog protein 1 Nicastrin Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Recombining binding protein suppressor of hairless S-phase kinase-associated protein 1 SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O15379 O60907 O75376 O76050 P01106 P0CG47 P0CG48 P24863 P46531 P49336 P49768 P49810 P56524 P62877 P62979 P62987 P63208 P78504 P78536 Q06330 Q09472 Q13495 Q13547 Q13573 Q13616 Q14469 Q5TA89 Q86YT6 Q8IZL2 Q8WUI4 Q8WW43 Q92542 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96AX9 Q96BI3 Q96DB2 Q96JK9 Q9BY41 Q9BZK7 Q9NQ87 Q9NR61 Q9NZ42 Q9UBN7 Q9UBP5 Q9UKV0 Q9UQL6 Q9Y219 Q9Y5J3 Q9Y618	AD3 AD4 ADAM10 ADAM17 APH1A APH1B BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BHLHE39 CBP CCNC CDK8 CG1 CHF1 CHF2 CREBBP CSVP CTG26 CUL1 CXorf6 DIP1 DLL1 DLL4 EMC19 EP300 GCN5 GCN5L2 GRL HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 IRA1 JAG1 JAG2 JAGL1 KAT2A KAT2B KIAA0200 KIAA0253 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1323 KIAA1816 KIAA1819 KUZ MADM MAML1 MAML2 MAML3 MAMLD1 MIB1 MIB2 MITR MYC NCOR1 NCOR2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH1 OCP2 P300 PCAF PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RBPJ RBPJK RBPSUH RBX1 RNF67 RNF75 ROC1 RPD3L1 RPS27A SKD SKIIP SKIP SKP1 SKP1A SNW1 STM2 TACE TAN1 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Vitamin D (calciferol) metabolism	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Cubilin E3 SUMO-protein ligase PIAS4 Legumain Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Vitamin D 25-hydroxylase Vitamin D-binding protein Vitamin D3 receptor	O15528 O60494 P02774 P11473 P61956 P63279 P98164 Q07973 Q5SW96 Q6VVX0 Q8N2W9 Q99538	ARH CUBN CYP1ALPHA CYP24 CYP24A1 CYP27B CYP27B1 CYP2R1 GC IFCR LDLRAP1 LGMN LRP2 NR1I1 PIAS4 PIASG PRSC1 SMT3B SMT3H2 SUMO2 UBC9 UBCE9 UBE2I VDR	Homo sapiens (human)
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 16 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase 2 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 5 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase 8 Dual specificity protein phosphatase 9 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3	P27361 P28482 P28562 Q05923 Q13115 Q13202 Q15121 Q16690 Q16828 Q16829 Q99956 Q9BY84 Q9Y6W6	C11orf81 CL100 DUSP1 DUSP10 DUSP16 DUSP2 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK1 ERK2 KIAA1700 MAPK1 MAPK3 MKP1 MKP2 MKP3 MKP4 MKP5 MKP7 PAC1 PEA15 PRKM1 PRKM2 PRKM3 PTPN10 PYST1 PYST2 VH1 VH2 VH3 VH5	Homo sapiens (human)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase	P16442 P19526 Q10981	ABO FUT1 FUT2 H HSC SEC2	Homo sapiens (human)
Defective PAPSS2 causes SEMD-PA	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2	O95340	ATPSK2 PAPSS2	Homo sapiens (human)
Autodegradation of Cdh1 by Cdh1:APC/C	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O00762 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13042 Q13200 Q15008 Q16401 Q16763 Q8NHZ8 Q92530 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1242 KIAA1406 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z	Homo sapiens (human)
EPHA-mediated growth cone collapse	Ephexin-1 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14950 O75116 P06241 P07947 P07948 P24844 P35579 P35580 P35749 P60660 P61586 Q13464 Q7Z406 Q8N5V2	ARH12 ARHA FYN JTK8 KIAA0619 KIAA0866 KIAA2034 LYN MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NGEF RHO12 RHOA ROCK1 ROCK2 YES YES1	Homo sapiens (human)
Axonal growth inhibition (RHOA activation)	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Myelin-associated glycoprotein Oligodendrocyte-myelin glycoprotein Proto-oncogene DBL Reticulon-4 Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P08138 P10911 P20916 P23515 P52565 P61586 Q96FE5 Q9NQC3	ARH12 ARHA ARHGDIA DBL GDIA1 GMA KIAA0886 LERN1 LINGO1 LRRN6A MAG MCF2 NGFR NOGO OMG OMGP RHO12 RHOA RTN4 TNFRSF16	Homo sapiens (human)
Pre-NOTCH Processing in the Endoplasmic Reticulum	GDP-fucose protein O-fucosyltransferase 1 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein O-glucosyltransferase 1	P46531 Q04721 Q8NBL1 Q99466 Q9H488 Q9UM47	C3orf9 CLP46 FUT12 INT3 KIAA0180 KTELC1 MDSRP NOTCH1 NOTCH2 NOTCH3 NOTCH4 POFUT1 POGLUT1 TAN1	Homo sapiens (human)

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