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slc39a8 solute carrier family 39 member 8 [ Danio rerio (zebrafish) ]

Gene ID: 100002893, updated on 4-Jan-2025

Summary

Official Symbol
slc39a8provided by ZNC
Official Full Name
solute carrier family 39 member 8provided by ZNC
Primary source
ZFIN:ZDB-GENE-050419-124
See related
AllianceGenome:ZFIN:ZDB-GENE-050419-124
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-264d7.2; si:ch211-195e19.2
Summary
Predicted to enable zinc ion transmembrane transporter activity. Acts upstream of or within manganese ion transmembrane transport. Predicted to be located in membrane. Is expressed in brain; eye; and spinal cord. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See slc39a8 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (11685225..11714229, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (11558027..11581825, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene probable N-acetyltransferase family 8 member 5 Neighboring gene N-acetyltransferase 8 Neighboring gene mannosidase, beta A, lysosomal Neighboring gene ubiquitin-conjugating enzyme E2D 3

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane  

General protein information

Preferred Names
metal cation symporter ZIP8
Names
ZIP8
solute carrier family 39 (zinc transporter), member 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    11685225..11714229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307205.4XP_009305480.1  metal cation symporter ZIP8

    UniProtKB/TrEMBL
    A0A8M3AYZ5
    Conserved Domains (1) summary
    pfam02535
    Location:108434
    Zip; ZIP Zinc transporter
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