Welcome to GlyCosmos!!

The GlyCosmos Portal is a Web portal aiming to integrate the glycosciences with the life sciences. It consists of Standards, Repositories and Data Resources, providing information about genes, proteins, lipids, pathways and diseases.

  1. Integrated list of glycan-related genes, including glycosyltransferases, hydrolases, etc. Gene Symbol Aliases include gene descriptions and names of orthologs.
    394512 Entries
  2. Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.
    120208 Entries
  3. Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.
    2433 Entries
  4. Glycolipid entries from the LIPID MAPS Structure Database (LMSD).
    6008 Entries
  5. The list of validated glycans extracted from GlyTouCan, updated weekly.
    244142 Entries
  6. Pathways from Reactome containing glycoproteins as annotated in UniProt. Search by pathway name, species, and protein name.
    11141 Entries
  7. List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.
    1885 Entries
  8. List of all species in GlyCosmos Resources.
    27263 Entries
  1. SugarDrawer is a simple user interface providing the basic functionality for drawing and searching glycan structures with known topology. Those who wish to draw more complex glycans can use the Web version of GlycanBuilder.
  2. Web-based user interface for GlycanBuilder, with all the functionality provided by the standalone version. Databases including GlyTouCan, GlyCosmos glycans and GlycoNAVI can also be searched.
  3. Glycan structure conversion tools between WURCS, GlycoCT, IUPAC, etc. Image generation and validation functionality are also available.
  4. GlycoMaple is a visualization tool for pathways. Glycogene expression data can be uploaded or selected from RNA-Seq data from the Human Protein Atlas. The expression values will be displayed in various glycan-related pathways.
  5. Visualization of glycome profiling data on human, mouse and zebrafish tissue samples.
  6. LM-GlycomeAtlas is a web tool visualizing the data from Lectin Array analyses by the Kuno Laboratory at AIST.
  7. Glycoanalysis by the three axes of MS and chromatography.
  8. Glycan structure alignment tool for multiple glycan structures to analyze their commonalities as glycan profiles.
  9. Glycan biosynthesis simulation tool.
  10. GRable is a software to estimate site-specific glycan compositions of glycopeptides, using an MS1-based glycoproteomic method named “Glyco-RIDGE” [Narimatsu et al. JPR2018].

YouTube Channel

Open GlyCosmos Channel

Other Related Resources
Alliance of Genome Resources

is a gene dataset, which contains curated genome information essential for the understanding of the genetics and genomic basis of human biology, health and disease.


describes the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds.


is a resource of analyzed glycan-array data.


is a knowledge management platform that integrates and standardizes the data of genes and mutations related to diseases from multiple sources. It covers entire range of human disease.


is a relational database which contains the HPLC elution positions for over 350 2-AB labelled N-glycan structures together with predicted products of exoglycosidase digestions.


is useful information about carbohydrate antigens, ie, glycoepitopes, and antibodies is organized as a compact encyclopedia.

Glycoinformatics Consortium (GLIC)

provides and maintains a centralized source of software and databases for glycoscientists.


is the glycomics section of the SIB Bioinformatics Resource Portal which provides access to scientific databases and software tools in different areas of life sciences.


is a platform integrating sources of information to help characterise the molecular components of protein glycosylation.


is a Web tool to simulate glycosylation pathways.


is a data integration and dissemination project for carbohydrate and glycoconjugate related data, retrieving information from multiple international data sources, integrating and harmonizing this data via a user friendly Web interface.

Human Phenotype Ontology

provides a standardized vocabulary of phenotypic abnormalities encountered in human disease.

The Human Protein Atlas

is a Swedish-based program initiated in 2003 with the aim to map all the human proteins in cells, tissues, and organs using an integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology.


is a proteomic database to integrate proteome datasets generated from multiple projects and institutions.


is a database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information, especially large-scale molecular datasets generated by genome sequencing and other high-throughput experimental technologies.

LIPID MAPS Gene/Proteome Database (LMPD)

is comprised of lipid-related genes and proteins.

LIPID MAPS Structure Database (LMSD)

is a relational database encompassing structures and annotations of biologically relevant lipids.


is a freely available database focused on interactions established by extracellular matrix proteins, proteoglycans and polysaccharides


Minimum Information Required for A Glycomics Experiment” guidelines for publishing glycomics-related research articles.

The O-GlcNAc Database

is a curated and scored database of papers on glycoproteins with O-GlcNAc modifications.


is part of the Japanese National Project on Protein Structural and Functional Analyses.


is a portal site that curates genome and marker information of various plant species. This is a list of the glycogenes computationally extracted from all plant genomes in PlantGARDEN.


is an effort from the HUPO Proteomics Standard Initiative (HUPO-PSI) to standardise the access to molecular interaction databases programmatically.


is an open chemistry database at the National Institutes of Health (NIH).


is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes.


provides information on known carbohydrate sequences to which pathogenic organisms (bacteria, toxins and viruses) specifically adhere.


is a repository of glycomics mass spectrometry data.


is a knowledge base for curated glycoconjugate information and their annotations.


is dedicated to the classification, curation and prediction of lectins.


is a freely available, comprehensive resource of high quality protein sequences and functional annotations.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.


Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01