Welcome to GlyCosmos!!

The GlyCosmos Portal is a Web portal aiming to integrate the glycosciences with the life sciences. It consists of Standards, Repositories and Data Resources, providing information about genes, proteins, lipids, pathways and diseases.

Data Resources
Glycogenes
Integrated list of glycan-related genes, including glycosyltransferases, hydrolases, etc.
Glycoproteins
Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.
Lectins
Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.
Glycolipids
Glycolipid entries from the LIPID MAPS Structure Database (LMSD).
Glycans
The list of validated glycans extracted from GlyTouCan, updated weekly.
Pathways
Pathways from Reactome containing glycoproteins as annotated in UniProt. Search by pathway name, species, and protein name.
Diseases
List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.
Organisms
List of all species in GlyCosmos Resources.
Other Related Resources
Glycoinformatics Consortium (GLIC)

provides and maintains a centralized source of software and databases for glycoscientists.

Glycomics@ExPASy

is the glycomics section of the SIB Bioinformatics Resource Portal which provides access to scientific databases and software tools in different areas of life sciences.

GlyConnect

is a platform integrating sources of information to help characterise the molecular components of protein glycosylation.

GlyGen

is a data integration and dissemination project for carbohydrate and glycoconjugate related data, retrieving information from multiple international data sources, integrating and harmonizing this data via a user friendly Web interface.

jPOST

is a proteomic database to integrate proteome datasets generated from multiple projects and institutions.

MIRAGE

Minimum Information Required for A Glycomics Experiment” guidelines for publishing glycomics-related research articles.

PDBj

is part of the Japanese National Project on Protein Structural and Functional Analyses.

PubChem

is an open chemistry database at the National Institutes of Health (NIH).

UniCarb-DB

is a repository of glycomics mass spectrometry data.

UniCarbKB

is a knowledge base for curated glycoconjugate information and their annotations.

UniProt

is a freely available, comprehensive resource of high quality protein sequences and functional annotations.

LIPID MAPS Gene/Proteome Database (LMPD)

is comprised of lipid-related genes and proteins.

LIPID MAPS Structure Database (LMSD)

is a relational database encompassing structures and annotations of biologically relevant lipids.

Reactome

is a freely available, open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes.

GlycoSim

is a Web tool to simulate glycosylation pathways.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01