There are two ways to obtain images for a GlyTouCan ID. If it is a new glycan that has not been processed yet by GlyCosmos, the converter page https://glycosmos.org/glycans/converter has a form where images can be generated from WURCS. Otherwise, static images are available, such as https://image.glycosmos.org/snfg/png/G79042KA.
Subsumption refers to the relationship between five levels of glycan types registered in GlyCosmos. The top level is "Fully-defined saccharide" which is a glycan whose glycosidic linkage information (including anomeric configuration and the carbon numbers of the monosaccharides which are linked) are identified. The second level is "Linkage-defined saccharide" which is a glycan which contains at least one linkage with identified information. The third level is "Topology" which is a glycan whose linkages are known (i.e., the monosaccharides that are linked are identified), but linkage conformations are all unknown. The fourth level is "Monosaccharide composition" which contains just the number of monosaccharides (with known stereospecificity, such as galactose, or N-acetylglucosamine), but no linkages are specified. The fifth level is "Base composition" which contains just the number of base types such as hexose, deoxyhexose, etc. and no linkages are specified. There could be considered a sixth level, which would simply be the mass of the glycan.
Because of the registration process by which glycans are submitted to GlyTouCan, there exists the rare possibility that invalid glycans are registered. Thus, GlyCosmos Glycans are guaranteed to be the validated dataset of glycans extracted from GlyTouCan at the time of the update release of GlyCosmos.
The source and date of retrieval of all data is available under at https://glycosmos.org/metadata.
Please view the video available from TogoTV (available in both English and Japanese).
While there are no full-time curators working on GlyCosmos, the staff working on accumulating the data do check that the data being retrieved can be trusted.
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
GlyCosmos Portal v4.0.0
Last updated: August 19, 2024