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CYB5R4 cytochrome b5 reductase 4 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100341357, updated on 17-Dec-2024

Summary

Gene symbol
CYB5R4
Gene description
cytochrome b5 reductase 4
See related
Ensembl:ENSOCUG00000007137
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
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Genomic context

See CYB5R4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 5 NC_091436.1 (88375351..88559175, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 12 NC_067385.1 (84819341..85003218, complement)

Chromosome 5 - NC_091436.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC138849641 Neighboring gene centrosomal protein 162 Neighboring gene melanocortin 2 receptor accessory protein 2 Neighboring gene cyclin-G1 pseudogene Neighboring gene ripply transcriptional repressor 2 Neighboring gene synaptosome associated protein 91 Neighboring gene U6 snRNA-associated Sm-like protein LSm6 pseudogene

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FAD binding PubMed 
enables cytochrome-b5 reductase activity, acting on NAD(P)H PubMed 
enables heme binding PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091436.1 Reference mOryCun1.1

    Range
    88375351..88559175 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008263160.4XP_008261382.1  cytochrome b5 reductase 4 isoform X2

    UniProtKB/TrEMBL
    A0A5F9CC71, G1SSF5
    Related
    ENSOCUP00000006172.3
    Conserved Domains (3) summary
    cd06183
    Location:277505
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
    cd06490
    Location:169255
    p23_NCB5OR; p23_like domain found in NAD(P)H cytochrome b5 (NCB5) oxidoreductase (OR) and similar proteins. NCB5OR is widely expressed in human organs and tissues and is localized in the ER (endoplasmic reticulum). It appears to play a critical role in maintaining ...
    pfam00173
    Location:56128
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
  2. XM_008263159.4XP_008261381.1  cytochrome b5 reductase 4 isoform X1

    UniProtKB/TrEMBL
    A0A5F9CC71, U3KPE1
    Related
    ENSOCUP00000027101.2
    Conserved Domains (3) summary
    cd06183
    Location:277518
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
    cd06490
    Location:169255
    p23_NCB5OR; p23_like domain found in NAD(P)H cytochrome b5 (NCB5) oxidoreductase (OR) and similar proteins. NCB5OR is widely expressed in human organs and tissues and is localized in the ER (endoplasmic reticulum). It appears to play a critical role in maintaining ...
    pfam00173
    Location:56128
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
  3. XM_070073824.1XP_069929925.1  cytochrome b5 reductase 4 isoform X5

    UniProtKB/TrEMBL
    A0A5F9CC71
  4. XM_070073822.1XP_069929923.1  cytochrome b5 reductase 4 isoform X3

    UniProtKB/TrEMBL
    A0A5F9CC71
  5. XM_070073823.1XP_069929924.1  cytochrome b5 reductase 4 isoform X4

    UniProtKB/TrEMBL
    A0A5F9CC71
  6. XM_070073825.1XP_069929926.1  cytochrome b5 reductase 4 isoform X6

    UniProtKB/TrEMBL
    A0A5F9CC71
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