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ITGB2 integrin subunit beta 2 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105575545, updated on 13-Mar-2024

Summary

Gene symbol
ITGB2
Gene description
integrin subunit beta 2
See related
Ensembl:ENSCATG00000039608
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
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Genomic context

See ITGB2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012004166.1 (14398141..14443970, complement)

NW_012004166.1Genomic Context describing neighboring genes Neighboring gene PTTG1 interacting protein Neighboring gene uncharacterized LOC105575541 Neighboring gene uncharacterized protein encoded by LINC01547-like Neighboring gene SLX9 ribosome biogenesis factor

Genomic regions, transcripts, and products

Genomic Sequence:
NW_012004166.1 Unplaced Scaffold Reference Caty_1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding PubMed 
enables integrin binding PubMed 
Component Evidence Code Pubs
located_in cell surface PubMed 
located_in focal adhesion PubMed 
part_of integrin complex PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012004166.1 Reference Caty_1.0

    Range
    14398141..14443970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012037488.1XP_011892878.1  integrin beta-2 isoform X5

    See identical proteins and their annotated locations for XP_011892878.1

    UniProtKB/TrEMBL
    A0A2K5N6R4, A0A2K5N6V0
    Conserved Domains (3) summary
    smart00187
    Location:32447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:622699
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:726766
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  2. XM_012037487.1XP_011892877.1  integrin beta-2 isoform X5

    See identical proteins and their annotated locations for XP_011892877.1

    UniProtKB/TrEMBL
    A0A2K5N6R4, A0A2K5N6V0
    Related
    ENSCATP00000033190.1, ENSCATT00000057462.1
    Conserved Domains (3) summary
    smart00187
    Location:32447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:622699
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:726766
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  3. XM_012037486.1XP_011892876.1  integrin beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A2K5N6V0
    Conserved Domains (3) summary
    smart00187
    Location:36451
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:626703
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:730770
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  4. XM_012037485.1XP_011892875.1  integrin beta-2 isoform X3

    See identical proteins and their annotated locations for XP_011892875.1

    UniProtKB/TrEMBL
    A0A2K5N6V0
    Conserved Domains (3) summary
    smart00187
    Location:42457
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:632709
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:736776
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  5. XM_012037482.1XP_011892872.1  integrin beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5N6V0
    Conserved Domains (3) summary
    smart00187
    Location:89504
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:679756
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:783823
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  6. XM_012037484.1XP_011892874.1  integrin beta-2 isoform X3

    See identical proteins and their annotated locations for XP_011892874.1

    UniProtKB/TrEMBL
    A0A2K5N6V0
    Conserved Domains (3) summary
    smart00187
    Location:42457
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:632709
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:736776
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  7. XM_012037490.1XP_011892880.1  integrin beta-2 isoform X5

    See identical proteins and their annotated locations for XP_011892880.1

    UniProtKB/TrEMBL
    A0A2K5N6R4, A0A2K5N6V0
    Related
    ENSCATP00000033192.1, ENSCATT00000057464.1
    Conserved Domains (3) summary
    smart00187
    Location:32447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:622699
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:726766
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  8. XM_012037491.1XP_011892881.1  integrin beta-2 isoform X6

    UniProtKB/TrEMBL
    A0A2K5N6V0
    Conserved Domains (3) summary
    smart00187
    Location:1378
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:553630
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:657697
    Integrin_b_cyt; Integrin beta cytoplasmic domain
  9. XM_012037483.1XP_011892873.1  integrin beta-2 isoform X2

    Conserved Domains (2) summary
    smart00187
    Location:89504
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:679750
    Integrin_B_tail; Integrin beta tail domain
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