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LOC115057907 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit [ Echeneis naucrates (live sharksucker) ]

Gene ID: 115057907, updated on 21-Dec-2023

Summary

Gene symbol
LOC115057907
Gene description
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit
See related
Ensembl:ENSENLG00000002444
Gene type
protein coding
RefSeq status
MODEL
Organism
Echeneis naucrates
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Carangiformes; Echeneidae; Echeneis
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Genomic context

See LOC115057907 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
21
Annotation release Status Assembly Chr Location
100 current fEcheNa1.1 (GCF_900963305.1) 17 NC_042527.1 (7697852..7711834, complement)

Chromosome 17 - NC_042527.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 8-like 2 Neighboring gene calcium-activated potassium channel subunit beta-3-like Neighboring gene calcium-activated potassium channel subunit beta-2-like Neighboring gene F-box-like/WD repeat-containing protein TBL1XR1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_042527.1 Chromosome 17 Reference fEcheNa1.1 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in cytoplasm PubMed 
part_of phosphatidylinositol 3-kinase complex, class IA PubMed 
part_of phosphatidylinositol 3-kinase complex, class IB PubMed 
located_in plasma membrane PubMed 

General protein information

Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Echeneis naucrates Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEcheNa1.1 Primary Assembly

Genomic

  1. NC_042527.1 Reference fEcheNa1.1 Primary Assembly

    Range
    7697852..7711834 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029525159.1XP_029381019.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

    UniProtKB/TrEMBL
    A0A665T4X1, A0A665V7U3, A0A665V8U7
    Related
    ENSENLP00000005160.1, ENSENLT00000005424.1
    Conserved Domains (5) summary
    cd08398
    Location:325484
    C2_PI3K_class_I_alpha; C2 domain present in class I alpha phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:526696
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    pfam00794
    Location:173292
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32107
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl21453
    Location:6951064
    PKc_like; Protein Kinases, catalytic domain
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