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pigo-1 GPI ethanolamine phosphate transferase 3 [ Caenorhabditis elegans ]

Gene ID: 172285, updated on 4-Jan-2025

Summary

Official Symbol
pigo-1
Official Full Name
GPI ethanolamine phosphate transferase 3
Primary source
WormBase:WBGene00016159
Locus tag
CELE_C27A12.9
See related
AllianceGenome:WB:WBGene00016159
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 2. Orthologous to human PIGO (phosphatidylinositol glycan anchor biosynthesis class O). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See pigo-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
18
Sequence:
Chromosome: I; NC_003279.8 (6061732..6068040, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RBR-type E3 ubiquitin transferase Neighboring gene E3 ubiquitin-protein ligase ari-1.1 Neighboring gene Methyl-CpG binding protein 2/3 C-terminal domain-containing protein Neighboring gene Histone H1 Neighboring gene Treslin STD domain-containing protein

General gene information

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process  
involved_in GPI anchor biosynthetic process  
Component Evidence Code Pubs
located_in endoplasmic reticulum  
is_active_in endoplasmic reticulum membrane  
located_in endoplasmic reticulum membrane  
located_in membrane  

General protein information

Preferred Names
GPI ethanolamine phosphate transferase 3
NP_491750.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6061732..6068040 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059349.7NP_491750.3  GPI ethanolamine phosphate transferase 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491750.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01966
    Conserved Domains (1) summary
    cd16023
    Location:52319
    GPI_EPT_3; GPI ethanolamine phosphate transferase 3, PIG-O
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