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pgm1 phosphoglucomutase 1 [ Danio rerio (zebrafish) ]

Gene ID: 394000, updated on 4-Jan-2025

Summary

Official Symbol
pgm1provided by ZNC
Official Full Name
phosphoglucomutase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1245
See related
Ensembl:ENSDARG00000013561 AllianceGenome:ZFIN:ZDB-GENE-040426-1245
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63718
Summary
Predicted to enable phosphoglucomutase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be active in cytosol. Is expressed in central nervous system; digestive system; myotome; notochord; and yolk syncytial layer. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Orthologous to human PGM1 (phosphoglucomutase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See pgm1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (32010183..32025200, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (32023269..32038286, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene cache domain containing 1 Neighboring gene receptor tyrosine kinase-like orphan receptor 1 Neighboring gene EF-hand calcium binding domain 7 Neighboring gene integrin subunit beta 3 binding protein

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Clone Names

  • MGC63718

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables intramolecular phosphotransferase activity  
enables magnesium ion binding  
enables metal ion binding  
enables phosphoglucomutase activity  
enables phosphoglucomutase activity  
Component Evidence Code Pubs
is_active_in cytosol  

General protein information

Preferred Names
phosphoglucomutase-1
NP_957319.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201025.1NP_957319.1  phosphoglucomutase-1

    See identical proteins and their annotated locations for NP_957319.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055219
    UniProtKB/TrEMBL
    Q7SXW7
    Related
    ENSDARP00000006510.7, ENSDART00000006417.8
    Conserved Domains (2) summary
    cd03085
    Location:5561
    PGM1; Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction, ...
    PLN02307
    Location:1561
    PLN02307; phosphoglucomutase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    32010183..32025200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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