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PXK PX domain containing serine/threonine kinase like [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 706573, updated on 17-Aug-2024

Summary

Official Symbol
PXKprovided by VGNC
Official Full Name
PX domain containing serine/threonine kinase likeprovided by VGNC
Primary source
VGNC:VGNC:76522
See related
Ensembl:ENSMMUG00000006432
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See PXK in Genome Data Viewer
Location:
chromosome: 2
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (114491462..114590226)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (83696518..83796355, complement)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 6, acylglycerol lipase Neighboring gene ribonuclease P/MRP subunit p14 Neighboring gene pyruvate dehydrogenase E1 subunit beta Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding PubMed 
enables actin binding PubMed 
enables phosphatidylinositol binding PubMed 
enables protein kinase activity PubMed 
Component Evidence Code Pubs
located_in early endosome PubMed 
located_in extrinsic component of endosome membrane PubMed 
located_in late endosome PubMed 

General protein information

Preferred Names
PX domain-containing protein kinase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    114491462..114590226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028844294.1XP_028700127.1  PX domain-containing protein kinase-like protein isoform X9

    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  2. XM_015130607.2XP_014986093.1  PX domain-containing protein kinase-like protein isoform X2

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  3. XM_015130609.2XP_014986095.1  PX domain-containing protein kinase-like protein isoform X4

    UniProtKB/TrEMBL
    A0A1D5RIC4, F7H2D9
    Related
    ENSMMUP00000060068.1, ENSMMUT00000071734.2
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  4. XM_028844290.1XP_028700123.1  PX domain-containing protein kinase-like protein isoform X5

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  5. XM_015130610.2XP_014986096.1  PX domain-containing protein kinase-like protein isoform X5

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  6. XM_028844291.1XP_028700124.1  PX domain-containing protein kinase-like protein isoform X6

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  7. XM_015130611.2XP_014986097.1  PX domain-containing protein kinase-like protein isoform X6

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  8. XM_015130606.2XP_014986092.1  PX domain-containing protein kinase-like protein isoform X1

    UniProtKB/TrEMBL
    F7H2D9, H9ET08
    Related
    ENSMMUP00000048328.1, ENSMMUT00000069355.2
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  9. XM_028844292.1XP_028700125.1  PX domain-containing protein kinase-like protein isoform X7

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  10. XM_015130613.2XP_014986099.1  PX domain-containing protein kinase-like protein isoform X7

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  11. XM_028844293.1XP_028700126.1  PX domain-containing protein kinase-like protein isoform X8

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  12. XM_015130614.2XP_014986100.1  PX domain-containing protein kinase-like protein isoform X8

    UniProtKB/TrEMBL
    F7H2D9
    Conserved Domains (2) summary
    cd06871
    Location:13132
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:198345
    PKc; Catalytic domain of Protein Kinases
  13. XM_015130608.2XP_014986094.1  PX domain-containing protein kinase-like protein isoform X3

    UniProtKB/TrEMBL
    G8F1P9
    Conserved Domains (2) summary
    cd06871
    Location:26123
    PX_MONaKA; The phosphoinositide binding Phox Homology domain of Modulator of Na,K-ATPase
    cd00180
    Location:189336
    PKc; Catalytic domain of Protein Kinases
  14. XM_028844295.1XP_028700128.1  PX domain-containing protein kinase-like protein isoform X10

    UniProtKB/TrEMBL
    G8F1P9
    Conserved Domains (2) summary
    cd00180
    Location:115262
    PKc; Catalytic domain of Protein Kinases
    cl02563
    Location:149
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
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