adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 11 - 20 of 38 in total
Gene ID Gene Symbol Description Source
3383 ICAM1 intercellular adhesion molecule 1
3557 IL1RN interleukin 1 receptor antagonist
3578 IL9 interleukin 9
3586 IL10 interleukin 10
3600 IL15 interleukin 15
3952 LEP leptin
4049 LTA lymphotoxin alpha
4153 MBL2 mannose binding lectin 2
4318 MMP9 matrix metallopeptidase 9
4582 MUC1 mucin 1, cell surface associated
Displaying entries 31 - 36 of 36 in total
Gene ID Gene Symbol Description Source
54409 Ramp2 receptor (calcitonin) activity modifying protein 2
56532 Ripk3 receptor-interacting serine-threonine kinase 3
74069 Serpina3a serine (or cysteine) peptidase inhibitor, clade A, member 3A
238393 Serpina3f serine (or cysteine) peptidase inhibitor, clade A, member 3F
238395 Serpina3j serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J
271047 Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
84007 C3ar1 complement C3a receptor 1
113959 C5ar1 complement C5a receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
192155 Sftpb surfactant protein B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024