onchocerciasis

Summary
Synonym
  • Infection by Onchocerca volvulus
  • Onchocerca volvulus infection
  • volvulosis
Definition
A filariasis that involves parasitic infection caused by the nematode Onchocerca volvulus, which is transmitted to humans through the bite of a blackfly of the genus Simulium. The worms spread throughout the body and, when they die, cause intense itching and a strong immune system response that can destroy nearby tissue. The symptoms include pruritus, dermatitis, blindness, onchocercomata (subcutaneous nodules), and lymphadenopathy.
Super Class
filariasis
Disease Ontology
DOID:11678
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying all 3 entries
Gene ID Gene Symbol Description Source
3113 HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3596 IL13 interleukin 13
Displaying all 2 entries
Gene ID Gene Symbol Description Source
14960 H2-Aa histocompatibility 2, class II antigen A, alpha
16163 Il13 interleukin 13
Displaying 1 entry
Gene ID Gene Symbol Description Source
116553 Il13 interleukin 13

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024