Dubin-Johnson syndrome

Summary
Synonym
  • Dubin Johnson syndrome
  • chronic idiopathic jaundice
Definition
A bilirubin metabolic disorder that involves elevated levels of unconjugated bilirubin without elevation of liver alanine transaminase and aspartate transaminase enzymes as a result of the deficient ability of hepatocytes to secrete conjugated bilirubin into the bile.
Super Class
bilirubin metabolic disorder
Disease Ontology
DOID:12308
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying 1 entry
Gene ID Gene Symbol Description Source
1244 ABCC2 ATP binding cassette subfamily C member 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
25303 Abcc2 ATP binding cassette subfamily C member 2
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
Q92887 ATP-binding cassette sub-family C member 2
Displaying 1 entry
UniProt ID Protein Name Source
Q63120 ATP-binding cassette sub-family C member 2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025